Receptors as Supramolecular Entities

1st Edition

Proceedings of the Biannual Capo Boi Conference, Cagliari, Italy, 7-10 June 1981

Editors: Giovanni Biggio Erminio Costa P. F. Spano
Hardcover ISBN: 9780080298047
eBook ISBN: 9781483155500
Imprint: Pergamon
Published Date: 19th September 1983
Page Count: 492
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Description

Advances in the Biosciences, Volume 44: Receptors as Supramolecular Entities exemplifies the concept of transmitter and cotransmitter interactions using GABA receptor as a model. The book contains papers on the interaction of sulpiride and other substituted benzamides with dopamine receptors where the result of receptor stimulation is not a stimulation of cyclic AMP formation. The text also offers a panoramic view of the concepts that are being elaborated to reach a better understanding of the function of the receptors for the most important neurotransmitters operative in brain.

Table of Contents


Introduction


Dopamine Receptors


Radioligand Binding Studies of Dopamine Receptors in the Central Nervous System


Inhibitory Coupling of Dopamine Receptors to Adenylate Cyclase in Rat Anterior Pituitary


Possible Functional Meaning of the Coexistence of ,Monoamines and Peptides in the Same Neurons: A Study on the Interactions Between Cholecystokinin-8 and Dopamine in the Brain


Behavioral Effects of Prolactin: The Involvement of Brain Dopamine


DA Autoreceptors in the Substantia Nigra: Their Involvement in the Control of Nigral DA Synthesis


Modifications of Dopamine Receptors in Rat Striatum after Chronic Administration of L-Dopa


D2 Receptors Modulating Dopamine Synthesis in Striatal Synaptosomes


Evidence Against the D1 and D2 Dopamine Receptor Hypothesis: Studies with Sulpiride


Sulpiride and Other Benzamides as Specific Antagonists at the D2 Dopamine Receptor


Estrogen Modulation of Dopamine Autoreceptors


Activation of Dopaminergic Neurons by Sulpiride


Functional Similarities Between Benzamides and Other Neuroleptics


Behavioral and Biochemical Effects in the Adult Rat After Prolonged Postnatal Administration of Cataleptogenic and Noncataleptogenic Neuroleptics


Biochemical Pharmacology of Dopamine Neurons Innervating the Neurointermediate Lobe of Pituitary Gland


Substituted Benzamide Drugs as Selective Agents for Distinguishing Cerebral Dopamine Receptor Subtypes


The Supramolecular Organization of Receptors for Gamma-Aminobutyric Acid (GABA)


Neurochemical Indices of GABA Utilization in the Nigrostriatal System


Role of GABAergic Mechanisms within Cerebellar Nucleus Fastigii in the Control of Posture and in the Mechanism of Action of Benzodiazepines


Age Induced Loss of the Functional Link Between Ben

Details

No. of pages:
492
Language:
English
Copyright:
© Pergamon 1983
Published:
Imprint:
Pergamon
eBook ISBN:
9781483155500
Hardcover ISBN:
9780080298047

About the Editor

Giovanni Biggio

Erminio Costa

P. F. Spano