Receptors and Centrally Acting Drugs Pharmacokinetics and Drug Metabolism

1st Edition

Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985

Authors:

  • E. S. Vizi
  • S. Fürst
  • G. Zsilla
  • Description

    Advances in Pharmacological Research and Practice, Volume 2: Receptors and Centrally Acting Drugs presents the proceeding of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the developments in the fields of receptors and centrally acting drugs as well as in pharmacokinetics and drug metabolism. Organized into two sections encompassing 25 chapters, this volume begins with an overview of prejunctional regulation of neuromuscular transmission. This text then explores the whole-body autoradiography that is used extensively in toxicological research and screening. Other chapters consider the three major classes of models used in pharmacokinetics. This book discusses as well the various aspects of melanin–drug interactions. The final chapter deals with the investigation on the melanin affinity of amphetamine derivatives. This book is a valuable resource for pharmacologists, pharmacokineticists, and researchers.

    Table of Contents


    Preface

    Section 3 Receptors and Centrally Acting Drugs

    Transmission and Receptors

    On the Scope and Mechanisms of Local Control of Neurotransmitter Secretion from Individual Varicosities of the Sympathetic Nerves of the Guinea-Pig and Mouse Vas Deferens

    The Topography of Cholinergic Transmission

    Subtypes of Muscarine Receptors in the Guinea-Pig Ileum

    Presynaptic Alpha-2 Adrenoceptors

    Postsynaptic Alpha-2 Adrenoceptors and Chemical Transmission

    The Effect of Nondepolarizing Muscle Relaxants on Transmitter Release at Peripheral Cholinergic Receptor Sites

    Subsensitivity of Presynaptic and Supersensitivity of Postsynaptic Dopaminergic Receptors as a Result of Repeated Administration of Antidepressant Drugs

    Modulation of Neurotransmitter Receptors and Drug Recognition Sites by Repeated Doses of (-)Deprenyl

    The Effect Of Antimuscarinic Drugs on Aggressive Behaviour and Convulsions Evoked by Carbachol: Unitary Concept or Different Sensitivities of Central Cholinoceptors

    Cholinesterase Inhibitors and Corticosteroids Interact with General Anaesthetics by Altering Central Cholinergic Mechanisms

    GABA Receptors in the Myenteric Plexus from Morphine-Tolerant Guinea-Pigs

    The Effect of L-Noradrenaline and Xylazine on the Release of Noradrenaline During K+ -Channel Inhibition is not Mediated Via α2-Adrenoceptors

    Design and Synthesis Of 5H-2,3-Benzodiazepines

    Modulation of 3H-Noradrenaline Release from Isolated Human Cystic Artery

    Neurotransmission in Larval and Parasitic Life: A Study on Schistosoma Mansoni

    GABA-Ergic Mechanisms in Anticonvulsive Activity of Hydroxylamine and Hydrazine Derivatives of Barbituric Acid

    Effect of Drugs Classif

    Details

    No. of pages:
    518
    Language:
    English
    Copyright:
    © 1986
    Published:
    Imprint:
    Pergamon
    Print ISBN:
    9780080341910
    Electronic ISBN:
    9781483151410