Receptors and Centrally Acting Drugs Pharmacokinetics and Drug Metabolism

1st Edition

Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985

Editors:

Description

Advances in Pharmacological Research and Practice, Volume 2: Receptors and Centrally Acting Drugs presents the proceeding of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the developments in the fields of receptors and centrally acting drugs as well as in pharmacokinetics and drug metabolism. Organized into two sections encompassing 25 chapters, this volume begins with an overview of prejunctional regulation of neuromuscular transmission. This text then explores the whole-body autoradiography that is used extensively in toxicological research and screening. Other chapters consider the three major classes of models used in pharmacokinetics. This book discusses as well the various aspects of melanin–drug interactions. The final chapter deals with the investigation on the melanin affinity of amphetamine derivatives. This book is a valuable resource for pharmacologists, pharmacokineticists, and researchers.

Table of Contents


Preface

Section 3 Receptors and Centrally Acting Drugs

Transmission and Receptors

On the Scope and Mechanisms of Local Control of Neurotransmitter Secretion from Individual Varicosities of the Sympathetic Nerves of the Guinea-Pig and Mouse Vas Deferens

The Topography of Cholinergic Transmission

Subtypes of Muscarine Receptors in the Guinea-Pig Ileum

Presynaptic Alpha-2 Adrenoceptors

Postsynaptic Alpha-2 Adrenoceptors and Chemical Transmission

The Effect of Nondepolarizing Muscle Relaxants on Transmitter Release at Peripheral Cholinergic Receptor Sites

Subsensitivity of Presynaptic and Supersensitivity of Postsynaptic Dopaminergic Receptors as a Result of Repeated Administration of Antidepressant Drugs

Modulation of Neurotransmitter Receptors and Drug Recognition Sites by Repeated Doses of (-)Deprenyl

The Effect Of Antimuscarinic Drugs on Aggressive Behaviour and Convulsions Evoked by Carbachol: Unitary Concept or Different Sensitivities of Central Cholinoceptors

Cholinesterase Inhibitors and Corticosteroids Interact with General Anaesthetics by Altering Central Cholinergic Mechanisms

GABA Receptors in the Myenteric Plexus from Morphine-Tolerant Guinea-Pigs

The Effect of L-Noradrenaline and Xylazine on the Release of Noradrenaline During K+ -Channel Inhibition is not Mediated Via α2-Adrenoceptors

Design and Synthesis Of 5H-2,3-Benzodiazepines

Modulation of 3H-Noradrenaline Release from Isolated Human Cystic Artery

Neurotransmission in Larval and Parasitic Life: A Study on Schistosoma Mansoni

GABA-Ergic Mechanisms in Anticonvulsive Activity of Hydroxylamine and Hydrazine Derivatives of Barbituric Acid

Effect of Drugs Classif

Details

No. of pages:
518
Language:
English
Copyright:
© 1986
Published:
Imprint:
Pergamon
Electronic ISBN:
9781483151410
Print ISBN:
9780080341910

About the editors