Receptors and Cellular Pharmacology

Receptors and Cellular Pharmacology

Proceedings of the Sixth International Congress of Pharmacology

1st Edition - January 1, 1976

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  • Editor: E. Klinge
  • eBook ISBN: 9781483157733

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Receptors and Cellular Pharmacology is a collection of the proceedings of the Sixth International Congress of Pharmacology held in Helsinki, Finland, on July 20-25, 1975 and organized by the Finnish Pharmacological Society. The papers explore developments relating to receptors and cellular pharmacology and address a wide range of topics such as the hydrophobic properties of the neuromuscular blocking agents and the use of toxins as tools in receptor studies. Comprised of 21 chapters, this volume begins with an introduction to histamine receptors, their pharmacological taxonomy and classification, their presence in the gastric mucosa, and their applications in medicine. The discussion then turns to pharmacological investigations on cells in culture; the acetylcholine receptor of intact and cultured chicken retina cells; actions of neurotoxins on the acetylcholine receptor; and the isolation and characterization of membrane receptors. Subsequent chapters deal with cyclic nucleotides as mediators of drug action, with particular reference to the mechanism of the relaxation-promoting effects of epinephrine on the mammalian heart. This book should be of interest to pharmacologists, internists, psychiatrists, neurologists, and anesthesiologists.

Table of Contents

  • Contributors


    Invited Lectures

    Histamine Receptors

    Pharmacological Investigations on Cells in Culture

    Hydrophobic Properties of the Neuromuscular Blocking Agents

    Toxins as Tools in Receptor Studies

    Snake Toxins as Tools to Study Cholinergic Receptors: Junctional and Extrajunctional Acetylcholine Receptors in Skeletal Muscle

    The Acetylcholine Receptor of Intact and Cultured Chicken Retina Cells

    Actions of Neurotoxins on the Acetylcholine receptor — Ionic Conductance Modulator Unit and on Sodium Channels

    Situation, Purification and Properties of Acetylcholine Receptors of Mammalian Striated Muscle

    Studies of the Nicotinic Acetylcholine Receptor from Torpedo Californica Electroplax

    Toxins as Tools in the Study of Ionic Channels of Nerve Membranes

    Membrane Receptors: Isolation and Characterization

    Biochemical Assays for Neurotransmitter Receptors in the Brain: Focus on γ-Aminobutyric Acid

    Vasopressin-Sensitive Adenylate Cyclase from the Mammalian Kidney

    Glucagon, VIP and Secretin Receptors

    The Use of Radiolabeled Ligands to Study β-Adrenergic Receptors

    Opiate Receptors and their Ligands

    Some Functional Properties of the Cholinergic Receptor Protein from Fish Electric Organ in its Purified, Membrane-Bound and Reassociated States

    Cyclic Nucleotides as Mediators of Drug Action

    Cyclic Nucleotides as Mediators of Drug Action — Opening Remarks

    Cyclic Nucleotides as Mediators of Drug Action

    Mechanism of the Relaxation-Promoting Effects of Epinephrine on the Mammalian Heart

    Cyclic Nucleotides and Smooth Muscle Function

    The Role of Cyclic Nucleotides and Calcium in the Control of Secretion

    Genetic and Functional Studies of the Cyclic AMP Receptor in a Cultured Mammalian Cell

    Concluding Remarks — Cyclic Nucleotides as Mediators of Drug Action

    Contents of Volumes 1—6

    Subject Index

Product details

  • No. of pages: 260
  • Language: English
  • Copyright: © Pergamon 1976
  • Published: January 1, 1976
  • Imprint: Pergamon
  • eBook ISBN: 9781483157733

About the Editor

E. Klinge

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