Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration - 1st Edition - ISBN: 9780123870032, 9780123870193

Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration, Volume 99

1st Edition

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Serial Volume Editors: Nigel Atkinson
Hardcover ISBN: 9780123870032
eBook ISBN: 9780123870193
Imprint: Academic Press
Published Date: 23rd September 2011
Page Count: 312
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Table of Contents

Seizure and Epilepsy: Studies of Seizure Disorders in Drosophila

I. Introduction

II. Seizure Studies in Drosophila

III. Genetic Suppression of Seizure Susceptibility in Drosophila

IV. Chemical Suppression of Seizure Susceptibility in Drosophila

V. Concluding Remarks. Seizure Studies in Flies: Insights From Mutant Analyses, and Comparisons With Human Seizures


Homeostatic Cont of Neural Activity: A Drosophila Model for Drug Tolerance and Dependence

I. Introduction

II. Behavioral Analysis of Rapid Drug Tolerance in Drosophila

III. BK Channels and the Production of Rapid Tolerance

IV. The Synaptic Connection

V. Closing Remarks


Attention in Drosophila

I. Introduction: the Problem of Attention in Nonhuman Animals

II. Classical Behavioral Approaches: Tethered Flight

III. Adaptations to Electrophysiology

IV. Related Behavioral Measures

V. Neural Substrates of Visual Attention in Drosophila

VI. Conclusion and Future Directions

The Roles of Fruitless and Doublesex in the Control of Male Courtship

I. Introduction

II. The Behavior

III. The Genes, the Neurons


Circadian Plasticity: From Structure to Behavior

I. Introduction

II. Transmitting Molecular Oscillations to Neuronal Networks

III. From Oscillating Networks to Coherent Circadian Behaviors

IV. Conclusions


Learning and Memory in Drosophila: Behavior, Genetics, and Neural Systems

I. Behavioral Measures of Learning and Memory in Drosophila

II. Neural Structures Implicated in Memory

III. Genetics of Olfactory Memory Formation

IV. Common and Specific Genetic Mechanisms in Olfactory, Visual, and Spatial Memory Formation

V. Conclusion


Studying Sensorimotor Processing With Physiology in Behaving Drosophila

I. Motivation

II. A Brief History of Physiology in the Adult Drosophila Brain

III. Physiology in Behaving Flies

IV. Results From Recording in Behaving Drosophila

V. Outlook for the Future


Modeling Human Trinucleotide Repeat Diseases in Drosophila

I. Introduction

II. Results

III. Conclusion

From Genetics to Structure to Function: Exploring Sleep in Drosophila

I. Introduction

II. Successful (and Less Successful) Screenings of Sleep Phenotypes in Flies

III. Identified Sleep Mutants Suggest a Link Between Sleep and Brain Plasticity, Especially in the Mushroom Bodies

IV. Distinct Circadian Neurons Promote Either Wake or Sleep

V. Fly Sleep and Hypotheses on Sleep Functions

VI. Closing Remarks



Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.

Key Features

  • Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist


Neuroscientists, neurologists, psychologists


No. of pages:
© Academic Press 2011
23rd September 2011
Academic Press
Hardcover ISBN:
eBook ISBN:


"Invaluable reading." --Nature

"A valuable addition to any library as current reference material for advanced undergraduates, graduate students, and professional scientists." --Choice

Ratings and Reviews

About the Serial Volume Editors

Nigel Atkinson