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Recent Advances in Neuropsycho-Pharmacology - 1st Edition - ISBN: 9780080263823, 9781483154725

Recent Advances in Neuropsycho-Pharmacology

1st Edition

Selected Papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum, Göteborg, Sweden, 22-26 June 1980

Editors: B. Angrist G. D. Burrows M. Lader
eBook ISBN: 9781483154725
Imprint: Pergamon
Published Date: 30th April 1981
Page Count: 414
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Recent Advances In Neuropsychopharmacology contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general practitioners. Part III examines blood platelets as a model system for central monoaminergic neurons. Part IV focuses on anxiety pathways in the brain. Part V considers prospects for a biochemical classification system in psychiatry. Part VI presents pharmacokinetic studies of psychotropic drugs. Part VI contains two papers on the renal function and renal histology of lithium patients on maintenance lithium therapy and pre-lithium patients; and the treatment of refractory schizophrenia.

Table of Contents

Psychostimulants in Psychiatric Research

Similarities in the Behavioral Effects of d-Amphetamine and Apomorphine in Selected Members of a Primate Social Colony

Effects on Behavior of Acute and Chronic Intracerebral Instillation of Dopamine Agonists

Noradrenaline, Dopamine and Mood

GABA: An Important Moderator and Mediator of Dopamine Dependent Behaviors

d-Amphetamine and Schizophrenia: Behavioral, Pharmacological and Physiological Evaluations

Relationships Between Responses to Dopamine Agonists, Psychopathology, Neuroleptic Treatment Response, and Need for Neuroleptic Maintenance in Schizophrenic Subjects

Dopaminergic Mechanisms in Affective Illness

Mental and Behavioral Stereotypies Elicited by Stimulant Drugs. Relation to the Dopamine Hypothesis of Schizophrenia, Mania and Depression

Effects of Methylphenidate on Interpersonal Perceptions

Sex, Plasma Prolactin and Plasma 3-Methoxy-4-Hydroxyphenylglycol (MHPG) Predict Heritable D-Amphetamine Excitation in Man

Evaluation of Psychotropic Drugs in General Practice

Depression in the Community

Assessment of Depression and the Non-Psychiatrist

General Practice Patients in Clinical Research: Relevant Issues

A Research Network of Walloon Psychiatrists Working Both on In- and Out-Patients for Specialists and General Practitioners

Organization and Methodological Aspects of Outpatient Studies

Psychopharmacological Aspects of Organic Diseases

Evaluation of Psychotropic Drugs in General Practice Discussion

Blood Platelets as a Model System for Central Monoaminergic Neurons


Methodological Approaches for the Comparative Study of Platelet and CNS Aminergic Function

Platelet Uptake of Serotonin in Pathological Conditions

The Kinetics of Serotonin Efflux from Human Blood Platelets, and how it is Influenced by Different Drugs In Vivo and In Vitro

Action of Neurotropic Agents on Platelet Membrane

Platelet Shape Change in Patients with Psychiatric Disorders and Treated with Phenothiazines, Thioxanthines3 Butyrophenones, Benzodiazepines, Tricyclic Antidepressants and ß-Adrenergic Blocking Agents

High Affinity Binding Sites for [3H] Imipramine in Human Brain and Platelet: Clinical Implications

Monoamine Oxidase Activity in Platelets as Related to Monoamine Oxidase Activity and Monoaminergic Function in the Brain

Neurone Specific Enolase (NSE) in Human Blood Platelets: Implications for the Neuronal Model

Platelet Neurotransmitter-related Enzymes in Psychopharmacologic Studies

Anxiety: Neurotransmitters, Pathways and Drugs

Introduction: Clinical Aspects Modulation of Benzodiazepine Receptors

Interactions of Anxiolytic Drugs with Benzodiazepine Receptors

Neuroanatomical Aspects of Anxiety

Animal Tests of Anxiety

Biochemistry of the Human CSF. Towards a Biochemical Classification of Psychiatric Disorders


Monoamine Metabolites in Cerebrospinal Fluid in Relation to Depressive Illness, Suicidal Behaviour and Personality

5-HTP and Lithium Prophylaxis in Uni- and Bi-Polar Depression

Cerebrospinal Fluid Amines and Peptides in Affective Illness

Cerebrospinal Fluid Norepinephrine and Dopamine-betahydroxylase in Affective Illness and Schizophrenia

CSF Tryptophane, 5-HIAA, and HVA in 132 Psychiatric Patients Categorized by Diagnosis and Clinical State

Relationships Between Aberrant Monoamine Metabolite Concentration in Cerebrospinal Fluid and Family Disposition for Psychiatric Disorders in Healthy and Schizophrenic Subjects

Suicide, Neuroendocrine Dysfunction and CSF 5-HIAA Concentrations in Depression

Spinal Fluid GABA Levels in Schizophrenia

Patterns of Urinary Peptide-protein Complexes in Patients Diagnosed as Anorexia Nervosa

Endorphin Measurements in Schizophrenia, a Progress Report

Pharmacokinetic Studies of Psychotropic Drugs

Pharmacokinetics of Tricyclic Antidepressants

Notes on Kinetics and Metabolism of Benzodiazepines

Pharmacokinetics of Antipsychotic Agents

Relationships Between Plasma Lithium Levels and Clinical and Biological Responses

Pharmacokinetic Studies of Psychotropic Drugs Lithium: Serum, RBC and CSF Levels

Additional Papers

Renal Biopsy Studies of Lithium, Pre-Uthium and Donor Kidneys

The Treatment of Refractory Schizophrenia (Blood Levels of Antipsychotic Agents)



No. of pages:
© Pergamon 1981
30th April 1981
eBook ISBN:

About the Editors

B. Angrist

G. D. Burrows

Affiliations and Expertise

Department of Psychiatry, The University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia

M. Lader

Ratings and Reviews