Rapid Acting Antidepressants

Rapid Acting Antidepressants

1st Edition - June 26, 2020

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  • Editors: Ronald S. Duman, John H. Krystal
  • eBook ISBN: 9780128201909
  • Hardcover ISBN: 9780128201893

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The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

Key Features

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series


Investigators in neuroscience, pharmacology, neurology, psychiatry, medicine

Table of Contents

  • Part I – Neurobiology of ketamine effects

      1. Effects of ketamine and other rapidly acting antidepressants on hippocampal excitatory and inhibitory transmission
      2. Allie J. Widman and Lori L. McMahon

      3. Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition
      4. Bernhard Luscher, Mengyang Feng and Sarah J. Jefferson

      5. The role of eEF2 kinase in the rapid antidepressant actions of ketamine
      6. Kanzo Suzuki and Lisa M. Monteggia

        Part II – The rapid therapeutic effects of ketamine

      7. Clinical overview of NMDA-R antagonists and clinical practice
      8. Pasha A. Davoudian and Samuel T. Wilkinson

      9. Ketamine for depression clinical issues
      10. Syed Z. Iqbal and Sanjay J. Mathew

      11. Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence
      12. Lynnette A. Averill, Samar Fouda, James W. Murrough and Chadi G. Abdallah

      13. Neurobiological biomarkers of response to ketamine
      14. Bashkim Kadriu, Elizabeth D. Ballard, Ioline D. Henter, Stephen Murata, Nimesha Gerlus and Carlos A. Zarate Jr

      15. Relapse prevention in treatment resistant major depressive disorder with rapid-acting antidepressants
      16. Jaskaran B. Singh, Maggie Fedgchin, Ella J. Daly and Wayne C. Drevets

      17. The emergence of ketamine as a novel treatment for posttraumatic stress disorder
      18. Adriana Feder, Sarah B. Rutter, Daniela Schille and Dennis S. Charney

        Part III – Novel rapid-acting antidepressant mechanisms related to ketamine

      19. mGlu2/3 receptor as a novel target for rapid acting antidepressants
      20. Shigeyuki Chaki

      21. Involvement of muscarinic receptor mechanisms in antidepressant drug action
      22. Jeffrey M. Witkin, Jodi L. Smith, Lalit K. Golani, Emily A. Brooks and Anna E. Martin

      23. The antidepressant efficacy of the muscarinic antagonist scopolamine: Past findings and future directions

    Wayne C. Drevets, Anindya Bhattacharya and Maura L. Furey

Product details

  • No. of pages: 402
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: June 26, 2020
  • Imprint: Academic Press
  • eBook ISBN: 9780128201909
  • Hardcover ISBN: 9780128201893

About the Serial Volume Editors

Ronald S. Duman

Ronald Duman is at Yale University School of Medicine, CT, USA

Affiliations and Expertise

Yale University School of Medicine, CT, USA

John H. Krystal

John Krystal is at Yale University, CT, USA

Affiliations and Expertise

Yale University, CT, USA

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