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Rapid Acting Antidepressants - 1st Edition - ISBN: 9780128201893, 9780128201909

Rapid Acting Antidepressants, Volume 89

1st Edition

Serial Volume Editors: Ronald S. Duman John H. Krystal
Hardcover ISBN: 9780128201893
eBook ISBN: 9780128201909
Imprint: Academic Press
Published Date: 26th June 2020
Page Count: 402
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Table of Contents

Part I – Neurobiology of ketamine effects

    1. Effects of ketamine and other rapidly acting antidepressants on hippocampal excitatory and inhibitory transmission
    2. Allie J. Widman and Lori L. McMahon

    3. Antidepressant mechanisms of ketamine: Focus on GABAergic inhibition
    4. Bernhard Luscher, Mengyang Feng and Sarah J. Jefferson

    5. The role of eEF2 kinase in the rapid antidepressant actions of ketamine
    6. Kanzo Suzuki and Lisa M. Monteggia

      Part II – The rapid therapeutic effects of ketamine

    7. Clinical overview of NMDA-R antagonists and clinical practice
    8. Pasha A. Davoudian and Samuel T. Wilkinson

    9. Ketamine for depression clinical issues
    10. Syed Z. Iqbal and Sanjay J. Mathew

    11. Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence
    12. Lynnette A. Averill, Samar Fouda, James W. Murrough and Chadi G. Abdallah

    13. Neurobiological biomarkers of response to ketamine
    14. Bashkim Kadriu, Elizabeth D. Ballard, Ioline D. Henter, Stephen Murata, Nimesha Gerlus and Carlos A. Zarate Jr

    15. Relapse prevention in treatment resistant major depressive disorder with rapid-acting antidepressants
    16. Jaskaran B. Singh, Maggie Fedgchin, Ella J. Daly and Wayne C. Drevets

    17. The emergence of ketamine as a novel treatment for posttraumatic stress disorder
    18. Adriana Feder, Sarah B. Rutter, Daniela Schille and Dennis S. Charney

      Part III – Novel rapid-acting antidepressant mechanisms related to ketamine

    19. mGlu2/3 receptor as a novel target for rapid acting antidepressants
    20. Shigeyuki Chaki

    21. Involvement of muscarinic receptor mechanisms in antidepressant drug action
    22. Jeffrey M. Witkin, Jodi L. Smith, Lalit K. Golani, Emily A. Brooks and Anna E. Martin

    23. The antidepressant efficacy of the muscarinic antagonist scopolamine: Past findings and future directions

Wayne C. Drevets, Anindya Bhattacharya and Maura L. Furey


The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

Key Features

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series


Investigators in neuroscience, pharmacology, neurology, psychiatry, medicine


No. of pages:
© Academic Press 2020
26th June 2020
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Volume Editors

Ronald S. Duman

Ronald Duman is at Yale University School of Medicine, CT, USA

Affiliations and Expertise

Yale University School of Medicine, CT, USA

John H. Krystal

John Krystal is at Yale University, CT, USA

Affiliations and Expertise

Yale University, CT, USA