Radiation Research

Radiation Research

Biomedical, Chemical, and Physical Perspectives

1st Edition - January 1, 1975

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  • Editors: Oddvar F. Nygaard, Howard I. Adler, Warren K. Sinclair
  • eBook ISBN: 9781483270074

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Radiation Research: Biomedical, Chemical and Physical Perspectives documents the proceedings of the Fifth International Congress of Radiation Research held in Seattle, Washington, 14-20 July 1974. While the focus of the Congress was on fundamental research, there were several well-attended sessions on the practical aspects of radiation research as it relates to radiotherapy, central station power generation by both nuclear fission and fusion, and the environment. This volume contains 126 papers organized into 31 parts. Beginning with a keynote address and a lecture on the time scale in radiobiology, the subsequent contributions cover a wide range of topics presented over several sessions. Topics discussed during these sessions include energy needs, nuclear power, and the environment; prospects for fusion power; technological applications of radiation; human radiobiology; hazards of radiation exposure relative to other environmental agents; the basic physics of the interactions of radiation with matter; particle penetration phenomena; and radiation effects in frozen media.

Table of Contents

  • Preface


    Officers and Organizing Committee

    Special Addresses

    Speech at Opening Ceremonies of the Fifth International Congress of Radiation Research

    The Time Scale in Radiobiology (Failla Memorial Lecture)

    Plenary Sessions

    Energy Needs, Nuclear Power and the Environment

    Energy Needs, Nuclear Power, and the Environment

    Prospects for Fusion Power

    Status and Future Prospects for Fusion Power

    Fusion Research in Japan

    Technological Applications of Radiation

    Technological Applications of Radiation—An IntroductionZ

    Applied Industrial Radiation Chemistry of Monomers and Polymers

    Mutations in Plant Breeding—A Glance Back and a Look Forward

    The Use of Ionizing Radiation for Preservation of Food and Feed Products

    Radiation Sterilization—An Industrial Process

    Human Radiobiology

    The Late Effects of Acute External Exposure to Ionizing Radiation in Man

    The Risk of Malignancy from Internally-Deposited Radioisotopes

    Reevaluation of Hazards of Radiation Exposure Relative to Other Environmental Agents

    Chemical and Radiation Carcinogenesis in Man and Experimental Animals

    Problems in the Reevaluation of Genetic Risks from Radiation and Other Environmental Hazards


    The Basic Physics of the Interactions of Radiation with Matter

    Introduction to the Symposium on the Basic Physics of the Interactions of Radiation with Matter


    Electron Energy Deposition in Matter at the Molecular Level

    Secondary Electron Spectra

    Ionization by Energy Transfer from Excited Species

    Ionization by Interpenetration of Electron Shells

    Spontaneous Breakup of Gaseous Ions

    Ion-Molecule Reactions

    Particle Penetration Phenomena

    Energy Loss and Ranges of Charged Particles in Matter

    Channeling: A Tool for the Study of the Interactions of Energetic Particles Penetrating Solids

    Transmission of Fast Molecules through Solids

    Primary Processes and Track Effects in Irradiated

    Electrons in Liquids

    The Optical Absorption Spectrum of the Solvated Electron in Polar Liquids and in Binary Solutions

    Theory of Optical Spectra of Solvated Electrons

    Electron Yields and Reaction Kinetics in Polar Liquids

    Reaction Rates of Electrons at Short Times

    Measured Mobilities of Electrons

    Energies of Conduction Bands in Dielectric Liquids

    Excess Electrons and Energy Fluctuations in the Non-Polar Liquids

    Mobilities of Slow Electrons in Low- and High-Pressure Gases and Liquids

    Radiation Effects in Frozen Media

    Ground State Structure of Trapped Electrons in Glassy Matrices

    Some Aspects of Electron Dynamics in Solid Alkanes

    Deferred Luminescence in Organic Matrices at Low and Very Low Temperatures

    Trapped Electrons and Anions in Rigid Organic Glasses at 4°K

    Reactions of Electrons in 3-Methylhexane Glass

    Formation and Decay of Trapped Electrons in Frozen Media

    Electron Tunneling in Rigid Media

    Fast Response Techniques in Chemistry and Biology

    Rapid-Mixing Studies on the Time-Scale of Radiation Damage in Cells

    Application of Fast Polarography in Pulse Radiolysis

    Catalysis of Electron and Electron Transfer Reactions in Micellar and Protein Systems

    The Picosecond Reactions of Electrons with Biologically Important Molecules

    Current Topics in Dosimetry

    International Intercomparison of Neutron Dosimetry

    Dosimetric Parameters and Terminology Relevant to Radiology

    Microdosimetry of Auger Electrons

    Particle Dosimetry by Track Etching with Applications to Apollo Astronauts and to Heavy Radionuclide Mapping in Biological Systems

    Photodynamic Inactivation of Macromolecules and Cells

    Psoralen Cross-Links in DNA: Biological Consequences and Cellular Repair

    Chemical Aspects of Photodynamic Action in the Presence of Molecular Oxygen

    The Effects of Photodynamic Action Involving Oxygen upon Biological Systems

    The Effects of UV Light on Genetic Functions

    Dissipation of UV Energy in Nucleic Acids and Nucleoproteins

    Genetic Effects of UV on Escherichia coli—A Model for Prokaryotes

    The Present Status of DNA Repair Mechanisms in UV Irradiated Yeast Taken as a Model Eukaryotic System

    Radiology Applied: Mapping Transcriptional Organization in Pro- and Eukaryotes

    The Eukaryotic Chromosome

    The Replication of Drosophila DNA: The Periodic Distribution of Replication Origins

    Mammalian Chromosome Structure: Ultrastructural Aspects of Specialized Regions and Chromosome Aberrations

    Structure and Replication of the Yeast Chromosome

    Repair Processes in Eukaryotes

    Repair Studies at the Molecular, Chromosomal, and Cellular Levels: A Review of Current Work in Japan

    DNA Damage and Its Repair in Hyperthermic Mammalian Cells: Relation to Enhanced Cell Killing

    Use of a Purified Lesion-Recognizing Enzyme to Assay DNA Repair in Cultured Animal Cells

    Carcinogens and DNA Repair

    Chemical Changes Induced in DNA by Ionizing Radiation and the Relationship of their Repair to Survival of Mammalian Cells

    Chemical Radiosensitization of Mammalian Cells

    Mammalian Cell Sensitization, Repair and the Cell Cycle

    Chemical Radiosensitization Studies with Mammalian Cells Growing In Vitro

    In Vivo Testing of Hypoxic Cell Radiosensitizers

    Chairman's Comments on the Discussion of Effects In Vivo

    Response of Stem Cells to Single Repeated and Continuous Irradiation

    Concept of Human Stem Cell Kinetics

    Response of Stem Cell Systems to Whole Body and Partial Body Irradiation

    Characteristics of the Stem Cell Population Surviving a Sublethal Exposure to Ionizing Radiation

    Cell Proliferation Changes in Tumor and Normal Tissue as a Result of Irradiation

    Changes in the Rate of Proliferation in Normal Tissue after Irradiation

    Cell Proliferation Changes in Hemopoietic Tissue as a Result of Irradiation or Drug Administration: The Control of Cell Proliferation in Hemopoietic Tissue

    The Importance of Proliferation Kinetics and Clonogencity of Tumor Cells for Volume Responses of Experimental Tumors after Irradiation

    Cell Proliferation Kinetics and Growth Rate of the Irradiated Human Tumors

    Carcinogenesis: Radiation and Other Agents

    Carcinogenesis by Ionizing Radiation and Lessons for Other Pollutants

    Mechanisms of Carcinogenesis

    Direct Evidence that Damaged DNA Results in Neoplastic Transformation—A Fish Story

    Immunology of Carcinogenesis and Its Relation to Radiation

    Mechanisms of Radiation Carcinogenesis

    The Interplay of Viruses and Radiation in Carcinogenesis

    Roles of Cellular and Humoral Immunity in Malignancy

    Macrophage Functions in Immune Responses to Tumors

    New Ways of Estimating Genetic Risks in Man

    The Use of Chromosome Aberrations for Predicting Genetic Hazards to Man

    Mutation and the Amount of Human I11 Health

    Use of the Mouse to Fill Gaps in Our Risk Assessments

    Comparison of the Mutagenic Effects of Chemicals and Ionizing Radiation

    A Comparison of the Mutagenic Effects of Chemicals and Ionizing Radiation (Chairman's Remarks)

    Determinants of the Mutagenic Specificity of Chemical and Physical Agents in Microorganisms

    Comparison of the Mutagenic Effects of Chemicals and Ionizing Radiation Using Drosophila Melanogaster Test Systems

    Comparison of the Mutagenic Effects of Chemicals and Ionizing Radiation in the Spermatogenic Cells of the Mouse

    Theoretical Approaches to Radiation Biology

    Biophysical Implications of Radiation Quality

    Analysis of Radiation-Induced Chromosome Aberrations

    Cell Cycle Kinetics and Radiation Therapy

    Theoretical Aspects and Implications of the Oxygen Effect

    The Significance of LET in Radiobiology

    Fundamental Aspects of LET in Radiobiology

    Energy Deposition in Small Volumes in Relation to Linear Energy Transfer (LET)

    The Dependence on LET of Various Types of Damage in Phage DNA in Relation to the Inactivation Efficiency

    The Dependence of RBE and OER on Neutron Energy for Damage to Mammalian Cells and Plant Systems

    RBE Values of Fast Neutrons for Damage to Organized Tissues in Experimental Animals

    The Use of Heavy Particles in Radiotherapy

    Biological Basis of Heavy Particle and Fast Neutron Radiotherapy

    The Middle Atlantic Neutron Therapy Trial

    A Preliminary Report of the MDAH-TAMVEC Neutron Therapy Pilot Study

    Clinical Experience of Therapy with Cyclotron Neutrons at the University of Washington

    The RBE for Fast Neutrons: The Link between Animal Experiments and Clinical Practice

    HZE Particle Effects in Manned Spaceflight

    Studies on the Effects of Cosmic HZE-Particles on Different Biological Systems in the Biostack Experiments I and II Flown on Board of Apollo 16 and 17

    Effects of Cosmic Heavy Ions on Artemia Egg-Development

    High-LET Particles in Manned Spaceflight—Preliminary Report

    Some Studies on Visual Perception and Pathologic Effects of Accelerated Heavy Ions

    Biological Effects of Accelerated Boron, Carbon and Neon Ions

    Transport and Fate of Radionuclides

    Radioecological Studies Applied to Electro Nuclear Siting

    Effects of Limnological Variables on Bioaccumulation Factors

    Effect of Some Important Physio-Ecological Factors on the Accumulation of Radionuclides by Freshwater Fish

    Transuranium Element Toxicity—Dose-Response Relationships at Low Exposure Levels

    Metabolism and Biological Effects in Rodents of Plutonium and Other Actinide Elements

    Late Effects of Inhaled Plutonium in Dogs

    Current Status of Information Obtained from Plutonium Contaminated People

    Doseresponse Relationship for Beagles Injected with 239Pu(IV) or 241Am III)

    Transuranium Element Toxicity—Dose-Response Relationships at Low Exposure Levels. Summary and Speculative Interpretation Relative to Exposure Limits

    Radiation and Photochemical Processes in the Atmosphere and Their Ecological Effects

    Some Aspects of Airborne Particles and Radiation in the Atmosphere

    The Oxides of Nitrogen with Respect to Urban Smog, Supersonic Transports, and Global Methane

    Gas-to-Particle Conversion in the Atmospheric Environment by Radiation-Induced and Photochemical Reactions

    Effects of Air Pollution on Ecological Processes

    Summary Plenary Session



    Cellular and Subcellular Biology

    Tissue and Animal Biology

    Author Index

    Subject Index

Product details

  • No. of pages: 1404
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9781483270074

About the Editors

Oddvar F. Nygaard

Howard I. Adler

Warren K. Sinclair

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  • semayat Thu Apr 08 2021

    effect of radiation

    main cause and there protection