Radiation Oncology and Radiotherapy Part B

Radiation Oncology and Radiotherapy Part B

1st Edition - February 1, 2023

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  • Editors: Ai Sato, Jeffrey Kraynak, Ariel Marciscano, Lorenzo Galluzzi
  • Hardcover ISBN: 9780323899475

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Description

Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics including CT-assisted focal irradiation of tumors in mice, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Cytofluorometric characterization of the lymphoid compartment of irradiated tumors, Cytofluorometric characterization of the myeloid compartment of irradiated tumors, Mass cytometry to characterize the immune infiltrate of irradiated tumors, Characterization of the immune infiltrate in irradiated mouse tumor by multiplex immunofluorescence, and much more. Other chapters cover Methods to study FOXP3+CD8+ cells in irradiated bone metastases, Luminex-based characterization of cytokine signaling by irradiated tumors, Explant-based assessment of anticancer immunity in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, and more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Cell Biology series
  • Includes the latest information on the topic of development, characterization and applications in CAR T Cells

Readership

Academic, researchers, government and industrial sectors

Table of Contents

  • 1. CT-assisted focal irradiation of tumors in mice
    Jeffrey Kraynak
    2. Methods to preserve correct dosimetry in small animal irradiators
    Ariel Marciscano
    3. Monitoring TGFbeta signaling in irradiated tumors
    Mary Helen Barcellos-Hoff
    4. Cytofluorometric characterization of the lymphoid compartment of irradiated tumors
    Sara Labiano
    5. Cytofluorometric characterization of the myeloid compartment of irradiated tumors
    Michele Mondini
    6. Mass cytometry to characterize the immune infiltrate of irradiated tumors
    Miguel Sanmamed
    7. Characterization of the immune infiltrate in irradiated mouse tumor by multiplex immunofluorescence
    Carlos E de Andrea
    8. Methods to study FOXP3+CD8+ cells in irradiated bone metastases
    Zachary S. Buchwald
    9. Luminex-based characterization of cytokine signaling by irradiated tumors
    Ariel Marciscano
    10. Explant-based assessment of anticancer immunity in irradiated tumors
    Michael Gough
    11. Pipeline to characterize the TCR repertoire of irradiated tumors
    Nils Rudqvist
    12. Pipeline to identify tumor neoantigens exposed by radiation
    Claire Lhuillier
    13. Methods to assess abscopal responses in mice
    Maria Esperanza Rodriguez Ruiz
    14. Monitoring the biodistribution of radiolabeled therapeutics in mice
    Edward K. Fung and Pat Zanzonico
    15. Methods to assess radiation-induced fibrosis in mice
    Deborah E. Citrin
    16. Methods to assess radiation-induced cardiotoxicity in mice
    Carmen Bergom
    17. Histological assessment of intestinal injury by radiation
    David Kirsch
    18. Methods to investigate CNS involvement in irradiated mice
    Marie-Catherine Vozenin
    19. Clonogenic assay to measure bystander cytotoxicity of targeted alpha-particle therapy
    Julie Constanzo
    20. MorphoMacro for in vivo and ex vivo quantitative morphometric analysis of microglia
    Ines Mendes Pinto

Product details

  • No. of pages: 312
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: February 1, 2023
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323899475

About the Serial Volume Editors

Ai Sato

Ai Sato is a research specialist at Stich Radiation Oncology, New York, NY, USA

Affiliations and Expertise

Stich Radiation Oncology, New York, NY, USA

Jeffrey Kraynak

Jeffrey Kraynak is a research laboratory specialist at Stich Radiation Oncology, New York, NY, USA.

Affiliations and Expertise

Stich Radiation Oncology, New York, NY, USA

Ariel Marciscano

Dr. Ariel E. Marciscano is an assistant professor of Radiation Oncology at Weill Cornell Medical College.

Affiliations and Expertise

Weill Cornell Medical College, New York, USA.

Lorenzo Galluzzi

Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

Affiliations and Expertise

Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

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