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Quality Control and Evaluation of Herbal Drugs

Name: Quality Control and Evaluation of Herbal Drugs
ISBN: 9780128133743

1st Edition

Evaluating Natural Products and Traditional Medicine

36 Reviews

Author: Pulok K. Mukherjee

Paperback ISBN: 9780128133743

eBook ISBN: 9780128133989

Imprint: Elsevier

Published Date: 29th May 2019

Page Count: 784

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Description

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development.

Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development.

Key Features

Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes
Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis
Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine
Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues
References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Readership

those involved in the fields of herbal medicine, traditional medicine, pharmaceutical sciences and natural product research. Researchers in the herbal drug industry and academicians studying relevant areas of plant sciences, analytical chemistry, medicinal chemistry, phyto-chemistry, alternative medicine, pharmacognosy, natural products and related fields will be benefited. Graduate and post graduate students and researchers in these areas but also will be useful to the technocrats in the industries and the legislators to know more about the methodologies developed for quality evaluation of herbal drugs

1. Traditional systems of medicines and harmonization
2. Ethnopharmacology and ethnomedicines-inspired drug development
3. Quality evaluation of herbal medicines: Challenges and opportunities
4. Qualitative analysis for evaluation of herbal drugs
5. Morphological and microscopical evaluations
6. Extraction and other downstream procedures for evaluation of herbal drugs
7. Bioactive phyto-components and their analysis
8. Thin layer chromatography for evaluation of herbal drugs
9. High performance thin layer chromatography (HPTLC) for analysis of herbal drugs
10. High performance liquid chromatography for analysis of herbal drugs
11. LC-MS: A rapid technique for understanding the plant metabolomic analysis
12. Chemo-profiling and marker analysis for quality evaluation of herbal drugs
13. Bioassay guided isolation and evaluation of herbal drugs
14. Enzyme inhibition studies for evaluation of herbal drugs
15. Evaluation of herbal drugs for antimicrobial and parasiticidal effects
16. Antiviral evaluation of herbal drugs
17. Plant metabolomics and quality evaluation of herbal drugs
18. Safety related quality issues for development of herbal drugs
19. Quality assurance of herbal drugs and stability testing
20. Phytopharmaceuitcals, nutraceuticals and their evaluation
21. Regulatory harmonization and good quality practices for development of herbal medicine

Details

No. of pages:: 784

Language:: English

Copyright:: © Elsevier 2019

Published:: 29th May 2019

Imprint:: Elsevier

Paperback ISBN:: 9780128133743

eBook ISBN:: 9780128133989

About the Author

Pulok K. Mukherjee

Prof. Pulok K. Mukherjee is a fellow of the Royal Society of Chemistry (FRSC), UK and the fellow of the National Academy of Science (FNASc) India. He is working as the Director of the School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. His work on integrated approaches for traditional medicine-inspired drug development through chemo-profiling, quality control, pharmaco-vigilance, safety surveillance, risk assessment has achieved worldwide acclaim. He has made significant contributions in the area of evaluation and validation of medicinal plants, Ethnopharmacology, and ethnomedicine. He has contributed over 200 publications in peer reviewed impact journals and has several patents. He has also published several well acclaimed books including Evidence-Based Validation of Herbal Medicine (Elsevier); Evaluation of Herbal Medicinal Products (Pharmaceutical Press), and many others. Prof. Mukherjee has been honoured with several awards and laurels from both the Government of India and abroad. For further details please visit www.pulokmukherjee.in.

Affiliations and Expertise

Director, School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India www.jaduniv.edu.in // www.pulokmukherjee.in Secretary, Society for Ethnopharmacology, India, Saktigarh, Jadavpur, India www.ethnopharmacology.in Associate Editor Associate Editor Journal of Ethnopharmacology, Elsevier Science, USA www.journals.elsevier.com/journal-of-ethnopharmacology

Ratings and Reviews

36 Reviews

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Reviews (36)

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Dr. L.

08/07/19

Best book for exploring quality control and evaluation of herbal drugs

I am delighted to share my views on this book written by Dr. Mukherjee. This book is very much essential considering the present scenario of high usage of herbal drugs throughout the world. While the demand for herbal drugs are increasing the need for quality control is also equally important. It's well known that the standardization of herbal preparations is a highly complex process and there is an urgent need to establish robust , accurate and reproducible analytical methods. Understanding the complexity of herbals and establishing such methods are highly essential meanwhile documenting these methods are equally essential. This this book will be more useful and attract readers due to its quality content and well framed structure. I congratulate the author for bringing this book at right time.

Dr. M.

08/07/19

Quality Control and Evaluation of Herbal Drugs

This book is an excellent version for academicians, researchers and industrialists those who are interested in herbal drugs. It's a good compilation of concepts requried for quality control and evaluation of herbal drugs. In the current scenario, there is a definite need of standardisation methodologies for herbal drug formulations as they are widely used worldwide for treatment of various diseases and for maintainenace of health. I am very much sure that this book will attract readers and will be beneficial for understanding the quality control and evaluation methods of herbal drugs.

Santanu B.

08/07/19

Quintessential reference for all who are passionate about natural products

I would like to thank Professor Mukherjee once again for writing this book. Quality control of natural product and ethnomedicine continues to be an unmet need. The major challenge in the development of natural products/ethnomedicine is standardization, which hinders its acceptability as an effective system of healthcare. Although, several books documented standardization process of natural product, a complete reference book was always missing. This book provides a complete snapshot of the quality evaluation process of herbal medicines, outlining the modern concepts, instruments and techniques. In depth description of the quality evaluation process makes this a must read for all students and researchers in the field of natural product and ethnomedicine. This book would also help the academicians, researchers, medicinal plant growers, industrialists, and the policymakers in healthcare system to understand the process of quality evaluation of herbal drugs. Therefore, all librarians should have this book in their list.

Dr. D.

21/06/19

A good book in Quality Control and Evaluation of Herbal Drugs

Quality Control and Evaluation of Herbal Drugs, the book written by Prof. Pulok K. Mukherjee is very useful for researchers and students who are interested in herbal drugs. This book will help the readers easy to understand about quality, safety, and efficiency of herbal drugs.

Wisanu M.

21/06/19

Quality Control and Evaluation of Herbal Drugs

The fantastic book on "Quality Control & Evaluation of Herbal Drugs" by Prof Pulok Mukherjee. The detail useful methodologies based on experimental data and will be very useful as a reference guide to conduct research and quality control of drugs.

Dr. M.

19/06/19

Quality Control and Evaluation of Herbal Drugs

The book is an excellent compilation of chapters dealing with application of cutting-edge techniques for evaluation of bioactivity, standardization, safety assessment and quality control and quality assurance of ethnomedicines and phytomedicines. A valuable reference book for students and research scholars working in the field of Natural Products, AYUSH & traditional medicines, the book also will serve a benchmark for furthering the prospects of natural drug products as safe & effective medicines.

I congratulate the author, Prof. Pulok Mukherjee for his stupendous & consistent efforts in the area of ethnopharmacology & ethnomedicines!

Prof.R.N.GUPTA I.

14/06/19

Dr.R.NGUPTA Ph.D.(Pharmacy). Eminent Pharmacist Award 2017. Best Pharmaceutical Scientist Award 2018 Reviewer of NFI, Advisory Committee member of

I have gone through the book 'Quality Control and Evaluation of Herbal Drugs.
First of all I CONGRATULATE author Dr Pulok Mukherjee to write such important and valuable book on herbal drugs as per the need of the hour..
The content of the book covers all the related aspects required for herbal drugs. After independence of India or say in modern era throughout the world , stress were put on quality assurance, and testing/ evaluation of allopathic medicines only . The evaluation of Ayurvedic and herbal / plant drugs were not given due importance due to non availibility of testing process too. several advanced instruments have been even included in Indian Pharmacoeipia in the testing of drugs ,so that proper quality parameters can be complied. But for herbal drug it was lacking. In this book the special stress is given on developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine. The inclusion of herbal drugs for evaluation purpose through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues are commendable.This book is in consice form and most valuable for formulators
Wishing all success.

Tapan M.

12/06/19

Quality Control & Evaluation of Herbal Drugs

The book on 'Qualty Control & Evaluation of Herbal Drugs' by Prof Pulok Mukherjee, an eminent researcher and Director, Studies of Natural Products Studies, Jadavpur University, Kolkata is a much needed and timely publication. The first edition of the book covers well written 21 Chapters spread into 784 pages covers drug development from natural resources. The book is a treasure house of new information on R&D from natural remedies.
The book will be useful for bioprospecting, drug discovery and development from from natural resources and Traditional Medicine. The book is highly recommended for researchers and students working in the field of herbal products and traditional medicine and also for policy makers.

Dr. K.

11/06/19

Quality Control and Evaluation of Herbal Drugs, A Need of the Hour

At the outset I would like to congratulate the authors for bringing out much needed book for quality evaluation of herbal drugs. Evaluation of herbal drug is a bottle neck and whatever amount of work done in this regard, it is short of complete evaluation. Therefore a thorough understanding of the drugs from natural origin and application of suitable methodology for evaluation is essential for a frugal analysis of drugs from nature.
This book, thus, covers a logical requirement for the understanding of herbal drugs and therefore starts with traditional systems of medicine. It covers a wide range of evaluations methods; conventional methods like, Morphology, microscopy, ash values, various indices etc., to hyphenated technologies like LC-MS; to metabolomics. Inclusion of therapeutic evaluation bio-activity guided isolation impressed me a lot more.
Over all a highly needed book and I would like to recommend this book to every educational institute across the globe.

Dr. T.

10/06/19

Excellent compilation of research methodologies in Phytopharmacology

The contents in the entire book will be an excellent resource to the scholars those who are pursuing their research in Ethnopharmacology both in industries and academic institutions. The author has amazingly incorporated and integrated useful methodologies based on experimental data and I am certain
that it will be very useful as a reference guide to conduct research in phytochemistry and phototherapy. I applaud the author for his novel thoughts and invested time in writing this book that will benefits many faculties, scholars and students. Thanks.

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