Psychophysiological States

Psychophysiological States

The Ultradian Dynamics of Mind-Body Interactions

1st Edition - November 8, 2007

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  • Author: David Shannahoff-Khalsa
  • eBook ISBN: 9780080555102
  • Hardcover ISBN: 9780123742759

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Our understanding of psychophysiological states are now more broadly defined by the inclusion of the lateralized ultradian rhythms of the autonomic and central nervous systems (ANS and CNS) that play a key regulatory role in mind-body states. These neural rhythms are a unique step in the evolution of the nervous system that have mostly been ignored or missed in our understanding of physiology, mental activities, brain rhythms, and in the treatment of psychiatric disorders. The multivariate physiological experiments reviewed in this book provide a new “big picture” for how the body’s major systems (ANS, CNS, neuroendocrine, cardiovascular, fuel-regulatory, gastrointestinal, immune) are regulated, integrated, and coordinated by the ANS via the hypothalamus during both waking and sleep. This discovery has implications for psychiatrists, psychologists, stress physiologists, cardiologists, sleep researchers, neuroscientists, neuroendocrinologists, cognitive scientists, and those interested in performance, anxiety, depression, schizophrenia, autism, and addictive and impulse control disorders. This book includes the translational neuroscience aspect of this discovery, including implications for vagal nerve stimulation studies.

Key Features

  • This book is a study in Lateralized rhythms and Ultradian rhythms and their context in the ANS-CNS, a very new field
  • Implications of these rhythms in Anxiety, Depression and Schizophrenia will be explored
  • The book will present theories of possible causes for the assignment of causal mechanisms of these lateralizations
  • The reader will understand the Nasal Cycle, the rhythmic; alternating side-to-side fluctuation in nasal airflow which is regulated by the ANS
  • Unilateral Forced Breathing techniques will be discussed
  • Vagal nerve stimulation and its effects will be discussed
  • Yoga breathing techniques are analyzed and theorized scientifically


Neuroscientists, psychiatrists, chronobiologists, physiologists, psychophysiologists, cognitive neuroscientists, therapists, sleep researchers, stress physiologists, and addiction specialists

Table of Contents

  • Introduction - An Historical Perspective on Psychophysiological States
    I. Towards an Integration of the Temporal and Structural Organization of Higher
    Vertebrates: Lateralized Ultradian Rhythms of the Nervous System
    I.A. Lateralized Rhythms of the Autonomic Nervous System
    I.B. Lateralized Rhythms of the Central Nervous System
    I.B.I. Ultradian Studies of Lateralized EEG During Sleep
    I.B.2. Ultradian Studies of Lateralized EEG During Waking
    I.B.3. Ultradian Studies of Lateralized Cognitive Performance Efficiency
    I.B.4. Studies of Lateralized Cognitive Performance After Awakening from
    REM and NREM Sleep Stages
    I.C. Ultradian Rhythms of the Cardiovascular, Neuroendocrine, Fuel-Regulatory,
    Gastrointestinal, and Immune Systems
    I.D. Hypothalamic Regulation and Integration of the ANS-CNS Rhythm and the
    Basic Rest Activity Cycle
    I.E. Ultradian Rhythms in Arousal, Performance, and Behavior
    II. A Neural Matrix for Coupling Mind and Metabolism
    III. A Pendulum of ANS-CNS Activities and Homeostasis: A New Paradigm for
    Stress and Disease
    IV. Implications of Lateralized Rhythms for Adaptation and Homeostasis
    V. Implications of Lateralized Rhythms for Psychopathology
    A. Anxiety
    B. Depression
    C. Schizophrenia
    VI. Translational Elements of Psychophysiological States: Regulation of
    Lateralized Autonomic and Central Nervous System Activities
    VI.A. Vagal Nerve Stimulation
    VI.A.1. Cognitive Abilities
    VI.B.2. Autonomic Physiology
    VI.B. Unilateral Forced Nostril Breathing
    VI.A.1. Cognitive Abilities
    VI.B.2. Autonomic Physiology
    VII. Conclusion
    VIII. References

Product details

  • No. of pages: 286
  • Language: English
  • Copyright: © Academic Press 2007
  • Published: November 8, 2007
  • Imprint: Academic Press
  • eBook ISBN: 9780080555102
  • Hardcover ISBN: 9780123742759

About the Author

David Shannahoff-Khalsa

Affiliations and Expertise

University of California, San Diego, USA

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