Psychophysiological States - 1st Edition - ISBN: 9780123742759, 9780080555102

Psychophysiological States, Volume 80

1st Edition

The Ultradian Dynamics of Mind-Body Interactions

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Authors: David Shannahoff-Khalsa
Hardcover ISBN: 9780123742759
eBook ISBN: 9780080555102
Imprint: Academic Press
Published Date: 8th November 2007
Page Count: 286
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Table of Contents

Introduction - An Historical Perspective on Psychophysiological States
I. Towards an Integration of the Temporal and Structural Organization of Higher
Vertebrates: Lateralized Ultradian Rhythms of the Nervous System
I.A. Lateralized Rhythms of the Autonomic Nervous System
I.B. Lateralized Rhythms of the Central Nervous System
I.B.I. Ultradian Studies of Lateralized EEG During Sleep
I.B.2. Ultradian Studies of Lateralized EEG During Waking
I.B.3. Ultradian Studies of Lateralized Cognitive Performance Efficiency
I.B.4. Studies of Lateralized Cognitive Performance After Awakening from
REM and NREM Sleep Stages
I.C. Ultradian Rhythms of the Cardiovascular, Neuroendocrine, Fuel-Regulatory,
Gastrointestinal, and Immune Systems
I.D. Hypothalamic Regulation and Integration of the ANS-CNS Rhythm and the
Basic Rest Activity Cycle
I.E. Ultradian Rhythms in Arousal, Performance, and Behavior
II. A Neural Matrix for Coupling Mind and Metabolism
III. A Pendulum of ANS-CNS Activities and Homeostasis: A New Paradigm for
Stress and Disease
IV. Implications of Lateralized Rhythms for Adaptation and Homeostasis
V. Implications of Lateralized Rhythms for Psychopathology
A. Anxiety
B. Depression
C. Schizophrenia
VI. Translational Elements of Psychophysiological States: Regulation of
Lateralized Autonomic and Central Nervous System Activities
VI.A. Vagal Nerve Stimulation
VI.A.1. Cognitive Abilities
VI.B.2. Autonomic Physiology
VI.B. Unilateral Forced Nostril Breathing
VI.A.1. Cognitive Abilities
VI.B.2. Autonomic Physiology
VII. Conclusion
VIII. References


Our understanding of psychophysiological states are now more broadly defined by the inclusion of the lateralized ultradian rhythms of the autonomic and central nervous systems (ANS and CNS) that play a key regulatory role in mind-body states. These neural rhythms are a unique step in the evolution of the nervous system that have mostly been ignored or missed in our understanding of physiology, mental activities, brain rhythms, and in the treatment of psychiatric disorders. The multivariate physiological experiments reviewed in this book provide a new “big picture” for how the body’s major systems (ANS, CNS, neuroendocrine, cardiovascular, fuel-regulatory, gastrointestinal, immune) are regulated, integrated, and coordinated by the ANS via the hypothalamus during both waking and sleep. This discovery has implications for psychiatrists, psychologists, stress physiologists, cardiologists, sleep researchers, neuroscientists, neuroendocrinologists, cognitive scientists, and those interested in performance, anxiety, depression, schizophrenia, autism, and addictive and impulse control disorders. This book includes the translational neuroscience aspect of this discovery, including implications for vagal nerve stimulation studies.

Key Features

  • This book is a study in Lateralized rhythms and Ultradian rhythms and their context in the ANS-CNS, a very new field
  • Implications of these rhythms in Anxiety, Depression and Schizophrenia will be explored
  • The book will present theories of possible causes for the assignment of causal mechanisms of these lateralizations
  • The reader will understand the Nasal Cycle, the rhythmic; alternating side-to-side fluctuation in nasal airflow which is regulated by the ANS
  • Unilateral Forced Breathing techniques will be discussed
  • Vagal nerve stimulation and its effects will be discussed
  • Yoga breathing techniques are analyzed and theorized scientifically


Neuroscientists, psychiatrists, chronobiologists, physiologists, psychophysiologists, cognitive neuroscientists, therapists, sleep researchers, stress physiologists, and addiction specialists


No. of pages:
© Academic Press 2008
8th November 2007
Academic Press
Hardcover ISBN:
eBook ISBN:


"This text presents a detailed and highly technical analysis of various ways that physiology overlaps with psychology." --European Association for Body Psychotherapy Newsletter

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About the Authors

David Shannahoff-Khalsa

Affiliations and Expertise

University of California, San Diego, USA