Psychopharmacological Agents, Volume II, provides an overview of the state of knowledge in psychopharmacological agents. The organization of this book is generally based on a treatment of the major classes of psychopharmacological agents in separate chapters. To the extent allowed by the diverse nature of the subject matter, each chapter covers the history, synthesis, pharmacological activity, in vivo distribution and metabolic fate, analytical methods, and, briefly, the clinical uses of each class of psychopharmacological agents.
This volume includes a chapter on the butyrophenones, one on miscellaneous psychopharmacological agents, and one on the biochemical basis of mental disease. The last named chapter is not exhaustive, but is merely meant to be illustrative of the currents of research that one finds in this field. The appendices have been used as a vehicle for collecting part of the part of the flood of reports that could not be included in either of the two volumes. Although written primarily for medicinal chemists and pharmacologists, researchers in other disciplines such as clinical investigation, biochemistry, analytical chemistry, etc., may also find material of interest here.
List of Contributors Foreword Preface to Volume I Preface to Volume II Contents of Volume I
- Phenothiazines I. Introduction II. Synthesis of the Phenothiazines III. Some Procedures for the Pharmacological Evaluation of Psychopharmacological Agents IV. Pharmacology of Ghlorpromazine V. Structure-Activity Relationships in the Phenothiazines VI. In Vivo Distribution and Metabolism of Phenothiazines VII. Analytical Methods for Phenothiazines VIII. Miscellaneous Properties of Phenothiazines IX. Summary of Clinical Applications References
- Haloperidol and Related Butyrophenones I. Origin II. Structure-Activity Relationships III. Pharmacological Activity of the Butyrophenones IV. Clinical Uses References
- Biochemical Basis of Mental Disease I. Introduction II. Theories of Mental Disease References
- Miscellaneous Psychotherapeutic Agents Text References Appendix A. Phenothiazine Bibliographies A.l Acetophenazine A.2 Carphenazine A.3 Fluphenazine A.4 Mepazine A.5 Methdilazone A.6 Methoxypromazine A.7 Perphenazine A.8 Pipamazine A.9 Prochlorperazine A.10 Promazine A.11 Propiomazine A.12 Prothipendyl A.13 Thiethylperazine A.14 Thiopropazate A.15 Thioridazine A.16 Trifluoperazine A.17 Triflupromazine A. 18 Trimeprazine Appendix B. Meprobamate-like Agents Bibliographies B.l Phenaglycodol B.2 Mephenoxalone B.3 Promoxalone B.4 Emylcamate B.5 Hydroxyphenamate B.6 Phenylpropanolcarbamate B.7 Metaxalone B.8 Methocarbamol B.9 Oxanamide B.10 Ectylurea B.ll Methyprylone B.l2 Ethchlorvynol Appendix C. Addenda to Volume I C.l Chlorprothixene C.2 Clinical Applications of the Monoamine Oxidase Inhibitors (Hydrazines): Addendum I. Mental Depression
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- © Academic Press 1967
- 1st January 1967
- Academic Press
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