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Psychopharmacological Agents, Volume IV summarizes the chemistry, pharmacology, and clinical manifestations of psychoactive drugs which are abused, with emphasis on opiate abuse and its treatment. The historical, legal, regulatory, and sociological aspects of the abuse of central nervous system agents are described, along with the treatment modalities that have evolved from some of these afflictions.
Comprised of six chapters, this volume begins with an introduction to drug abuse and drug dependence, followed by a discussion on various perspectives in drug abuse and modalities for treating patients who are dependent on opiates. Studies on non-abusive analgetics such as opium compounds are then reviewed, together with the chemistry, mechanism of action, and medical applications of psychotomimetic drugs. The final two chapters deal with the treatment of opiate abuse by methadone maintenance and the regulatory aspects of drug abuse.
This book will be of interest to students, practitioners, and researchers in medicinal chemistry, psychology, and pharmacology.
List of Contributors
Contents of Previous Volumes
Abbreviations Used in Text
1. Introduction to Drug Abuse and Drug Dependence
II. Drug Abuse
III. Drug Dependence
2. Perspectives in Drug Abuse
II. Heroin (Opiate)
III. Modalities for Dealing with Opiate Abuse
3. Research Toward Nonabusive Analgetics
II. Compounds from Opium
III. Analgetics Obtained by Total Synthesis
IV. Structure-Activity Concepts and Perspectives
4. Psychotomimetic Agents
II. Chemistry and Descriptions of the Psychotomimetic Drugs
III. Mechanism of Action
IV. Medical Applications and Hazards
5. Treatment of Opiate Abuse by Methadone Maintenance
II. Historical Background
III. Selection of Patients
IV. Description of Patients
V. Protocol for Treatment
VI. Goals of Treatment
VII. Evidence of Success: Positive Aspects
VIII. Evidence of Failure: Negative Aspects
IX. Methadone Maintenance During Pregnancy
X. Treatment of Adolescents
XI. Summary and Clinical Applications
6. Regulatory Aspects of Drug Abuse
- No. of pages:
- © Academic Press 1976
- 1st January 1976
- Academic Press
- eBook ISBN: