Psychedelic Neuroscience

Psychedelic Neuroscience

1st Edition - November 21, 2018

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  • Editor: Tanya Calvey
  • eBook ISBN: 9780128142561
  • Hardcover ISBN: 9780128142554

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We are in the midst of what is being called the ‘psychedelic renaissance’ with growing interest into how psychedelics alter consciousness, brain function and brain connectivity. The acute, often profound, effects of the psychedelic experience can induce lasting improvements in mental health demonstrating that chemistry forms the basis of mystical experience, consciousness and mental wellbeing.

Key Features

  • This volume is a collection of chapters by world leaders in fields of neurobiology, neuropsychiatry, psychology, ethnography and pharmacology, addressing the neurobiological mechanisms of action of various classic and atypical psychedelics, their therapeutic potential as well as the possible risks associated with their use


Policy makers, mental health practitioners, neuroscience researchers, researchers from various fields of health science and the humanities, members of the public and psychonauts

Table of Contents

  • 1. An introduction to psychedelic neuroscience
    Tanya Calvey and Fleur M. Howells
    2. The renaissance in psychedelic research: What do preclinical models have to offer
    Kevin S. Murnane
    3. D-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders
    Danilo De Gregorio, Justine P. Enns, Nicolas A. Nuñez, Luca Posa and Gabriella Gobbi
    4. Common neural signatures of psychedelics: Frequency-specific energy changes and repertoire expansion revealed using connectome-harmonic decomposition
    Selen Atasoy, Jakub Vohryzek, Gustavo Deco, Robin L. Carhart-Harris and Morten L. Kringelbach
    5. A case report SPECT study and theoretical rationale for the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder
    Joseph Barsuglia, Martin Polanco, Robert Palmer, Benjamin Malcolm, Benjamin Kelmendi and Tanya Calvey
    6. Advances and challenges in neuroimaging studies on the effects of serotonergic hallucinogens: Contributions of the resting brain
    Felix Müller, Matthias E. Liechti, Undine E. Lang and Stefan Borgwardt
    7. Neurocognitive effects of cannabis: Lessons learned from human experimental studies
    Marco Colizzi and Sagnik Bhattacharyya
    8. Ibogaine as a treatment for substance misuse: Potential benefits and practical dangers
    John Martin Corkery

Product details

  • No. of pages: 261
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: November 21, 2018
  • Imprint: Academic Press
  • eBook ISBN: 9780128142561
  • Hardcover ISBN: 9780128142554

About the Editor

Tanya Calvey

Dr. Tanya Calvey has a background in evolutionary neurobiology and lectures morphological anatomy in the Faculty of Health Sciences, University of the Witwatersrand. Tanya’s current research is on the neuropsychopharmacology of ibogaine and substance use disorders in humans and animals. Her research team is multidisciplinary and her research is funded by the South African Medical Research Council, the South African National Research Foundation and the International Society for Neurochemistry. Tanya is also actively involved in developing neuroscience research in Africa. She is the Secretary of the Southern African Neuroscience Society and the co-founder of the Wits Cortex Club.

Affiliations and Expertise

University of Witwatersrand, South Africa

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