
Proteolytic Signaling in Health and Disease
Description
Key Features
- Examines biological events triggered by proteolytic enzyme activity across human development and pathologies
- Discusses the role of proteolytic signaling in inflammation, wound healing, and cancer, among other disease types
- Features methods and protocols supporting further study of proteolytic signaling events
- Includes chapter contributions from international leaders in the field
Readership
Table of Contents
1. Proteolytic signalling: an introduction
André Zelanis, Uilla Barcick and Maurício F. Camacho
2. Ubiquitin-ligases: proteolytic signaling, protein turnover, and disease
Felipe Roberti Teixeira, Patricia Passos, Camila Correia, Caio Almeida, Valentine Spagnol and Isabela Fernanda Morales Martins
3. Lysosomal proteases and their role in signaling pathways
Rebecca A.B. Burton, Samuel Bose and Thamali Ayagama
4. Antigen processing and presentation through MHC molecules
Niels Olsen Saraiva Câmara, Tamisa Honda and Barbara Padovani
5. Proteolytic processing in autophagy
João Agostinho Machado-Neto and Andrei Leitão
6. Proteolysis in inflammatory diseases
Antoine Dufour and Luiz de Almeida
7. Proteolytic processing of laminin and the role of cryptides in tumoral biology
Vanessa Morais Freitas, Ruy Gastaldoni Jaeger and Adriane Sousa de Siqueira
8. Proteolytic signaling in wound healing
Ulrich auf dem Keller, Konstantinos Kalogeropoulos and Louise Bundgaard
9. Proteinases disbalance in oral cancer and other diseases
Adriana Franco Paes Leme
10. ‘Omics’ approaches for investigating protease degradomes in complex biological matrices
Pitter F. Huesgen and Maithreyan Kuppusamy
11. Protease web
Nikolaus Fortelny and Wolfgang Esser-Skala
12. The puzzle of proteolytic effects in hemorrhage induced by Viperidae snake venom metalloproteinases
Milene Menezes, Dilza Trevisan-Silva, Daniela Cajado De Oliveira Souza Carvalho and Jessica de Alcantara Ferreira
Product details
- No. of pages: 308
- Language: English
- Copyright: © Academic Press 2021
- Published: October 13, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780323856966
- eBook ISBN: 9780323856973
About the Editor
Andre Zelanis
Affiliations and Expertise
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