Proteinases and their Inhibitors: Structure, Function, and Applied Aspects documents the proceedings of an international symposium organized by the Department of Biochemistry, Jozef Stefan Institute, E. Kardelj University, Ljubljana, and the Department of Organic Chemistry and Biochemistry, Rudjer Boskovic Institute, Zagreb, held in Portoroz, Yugoslavia, September 29-October 3, 1980.
The volume contains 34 papers that are organized into four parts. Part I on biological functions includes studies such as muscle protein breakdown in human catabolic state and age-dependent changes in intracellular protein turnover. The papers in Part II, which deals with properties and structure of enzymes, cover topics such as structures and biological functions of cathepsin B and L; and human erythrocytes peptidases. Part III is devoted to industrial applications, such as exogenous proteinases in dairy technology and the application of immobilized proteinases. Part IV on proteinase inhibitors includes papers on thiol inhibitors of proteases and and intracellular neutral proteinases and inhibitors.
The papers in this volume provide new data, concepts, and visions which will not only prove useful, but will also stimulate further investigations of proteinases and their inhibitors.
List of Contributors Preface Biological Functions Muscle Protein Breakdown in Human Catabolic States Lysosomal Proteinases in Cultured Muscle Cells Age-Dependent Changes in Intracellular Protein Turnover On the Metabolism of Opiate Peptides by Brain Proteolytic Enzymes Malignancy and Tumor Proteinases: Effects of Proteinase Inhibitors Proteolysis and Catabolite Inactivation in Yeast Converting Enzyme of Fructose-1,6-Bisphosphatase from Rat Liver Synthesis of Plasminogen Activator by Cycling Cells Properties and Structure of Enzymes Structures and Biological Functions of Cathepsin B and L Cathepsin L Human Cathepsins B and H: Assay, Active-Site Titration and Selective Inhibition The Bovine Cysteine Proteinases, Cathepsin B, H and S Structural and Denaturation Studies of Cathepsin D and the Existence of its Possible Precursor Chicken Pepsin: Structure and Homology with Other Acid Proteinases Non-Covalent Intermediates in Catalysis by Proteolytic Enzymes A Different Form of the Ca2+-Dependent Proteinase Activated by Micromolar Levels of Ca2+ Characterization of Two Alkaline Proteinases from Rat Skeletal Muscle Human Erythrocytes Peptidases Serine Proteinases of Microorganisms Streptomyces rimosus Alkaline and Trypsin-like Serine Proteinases Purification, Properties and Application of Thermitase, a Microbial Serine Protease Comparative Specificity of Microbial Acid Proteinases Proteases in Culture Filtrates of Asperqillus niqer and Claviceps purpurea Industrial Application The Variety of Serine Proteases and Their Industrial Significance Exogenous Proteinases in Dairy Technology Pepsin-like Proteinases and Their Precursors Rennet Substitutes for Cheese Making Enzyme Actions in the Conditioning of Meat Preparation and Application of Immobilized Proteinases Proteinase Inhibitors Thiol Inhibitors
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- © Pergamon 1981
- 1st January 1981
- eBook ISBN: