Skip to main content

Save up to 30% on Elsevier print and eBooks with free shipping. No promo code needed.

Save up to 30% on print and eBooks.

Protein Folding in Silico

Protein Folding Versus Protein Structure Prediction

  • 1st Edition - October 4, 2012
  • Editor: Irena Roterman-Konieczna
  • Language: English
  • Hardback ISBN:
    9 7 8 - 1 - 9 0 7 5 6 8 - 1 7 - 6
  • eBook ISBN:
    9 7 8 - 1 - 9 0 8 8 1 8 - 2 5 - 6

Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first… Read more

Protein Folding in Silico

Purchase options

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote
Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.