
Protein Flexibility and Folding, Volume 1
1st Edition
Secure Checkout
Personal information is secured with SSL technology.Free Shipping
Free global shippingNo minimum order.
Table of Contents
Flexibility and Dynamics. Applications of NMR for the characterization of protein dynamics and folding (C. Bracken).
Observation and simulation to study mechanical properties of proteins (B. Isralewitz et al.).
Intrinsically disordered proteins (A.K. Dunker et al.).
Predicting flexibility in proteins using constraint theory (M.F. Thorpe et al.). Structure and dynamics of 6-hydroxymethyl-7, 8-dihydropterin pyrophosphokinase (H. Yan et al.).
Sampling activated mechanisms in proteins with the activation-relaxation technique (N. Mousseau et al.).
Folding and Unfolding. Constructing smooth potential functions for protein folding (G.M. Crippen).
Hydrogen exchange and protein folding (C. Woodward et al.).
Structural transitions in neutral and charged proteins in vacuo (G.A. Arteca, O. Tapia).
Capture and identification of folding intermediates of cystinyl proteins (J. Throck Watson et al.).
Solid state NMR studies of membranes and membrane-bound systems (J. Yang et al.).
Molecular simulations and acid-induced protein unfolding (W. Cornell et al.). Molecular dynamics simulations on protein folding and protein structure prediction (P. Kollman).
Evolution and Design. Evolutionary perspectives on protein folding and stability (P.D. Williams et al.).
The designability of protein structures (R. Helling et al.).
Comparing protein structures: a Gaussain-based approach to the three-dimensional similarity of proteins (G.M. Maggiora et al.).
Description
The papers in this volume are from the workshop on Protein Flexibility and Folding held in Traverse City, Michigan from August 13 - 17, 2000. The purpose of the workshop was to bring together diverse people interested in protein folding and flexibility from theoretical, computational and experimental perspectives and to encourage discussion on new approaches and challenges in the field. The workshop was held in the Park Plaza Hotel with 43 participants, including 24 invited speakers. The small size of the group made for easy exchanges, and many of the presentations by the invited speakers appear in this volume. There was also a very lively poster session. The three-day workshop was organized so that the first day covered Flexibility and Dynamics, the second day Folding and Unfolding, and the third day Evolution and Design. This area of science is particularly appealing as it spans a range of questions from very fundamental - as to how proteins fold in such short times with such reliability - to applications such as the role of flexibility in screening for new ligands to a protein. Protein flexibility and folding have attracted the attention of scientists from many disciplines, ranging from mathematics to molecular biology. The scientists at the workshop represented the breadth of challenges in theory and applications that keep this field so fascinating and dynamic. The present volume is organized along these same lines.
Readership
For scientists interested in protein folding and flexibility from theoretical, computational and experimental perspectives, including chemists involved in molecular modelling, molecular biologists, computational chemists, protein and polymer engineers and pharmaceutical scientists.
Details
- No. of pages:
- 184
- Language:
- English
- Copyright:
- © Elsevier Science 2001
- Published:
- 27th July 2001
- Imprint:
- Elsevier Science
- Hardcover ISBN:
- 9780444508164
- eBook ISBN:
- 9780080929705
Ratings and Reviews
About the Authors
L.A. Kuhn
M.F. Thorpe
Request Quote
Tax Exemption
Elsevier.com visitor survey
We are always looking for ways to improve customer experience on Elsevier.com.
We would like to ask you for a moment of your time to fill in a short questionnaire, at the end of your visit.
If you decide to participate, a new browser tab will open so you can complete the survey after you have completed your visit to this website.
Thanks in advance for your time.