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Prolactin - 1st Edition - ISBN: 9780124472082, 9780323159258


1st Edition

Editor: Choh Hao Li
eBook ISBN: 9780323159258
Imprint: Academic Press
Published Date: 28th June 1980
Page Count: 246
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Hormonal Proteins and Peptides: Prolactin, Volume VIII focuses on the broad spectrum of biological activities of prolactin among the vertebrates. This book discusses the function of prolactin in stimulating crop milk formation in birds as well as in inducing incubation behavior in the ring dove. Organized into five chapters, this volume starts with an overview of the chemistry of prolactin and its role on normal mammary gland growth and function. This text then explores the prolactin effects in tumor induction and growth. Other chapters review the status of the evolutionary biology and comparative endocrinology of prolactin. This book discusses as well the nature of prolactin cells, the control of prolactin secretion, and the nature of the prolactins from various vertebrate sources. The final chapter considers the significant advances in gonadotropins, including prolactin, follitropin, relaxin, and lutropin. This book is a valuable resource for biologists, endocrinologists, zoologists, embryologists, physicians, and medical health professionals.

Table of Contents

List of Contributors


Contents of Previous Volumes

1 The Chemistry of Prolactin

I. Introduction

II. Isolation Procedures

III. Characterization of Ovine and Porcine Prolactin

IV. Alkaline Titration by CD and Fluorescence in Comparison with HGH and HCS

V. Immunochemical Properties

VI. Primary Structure

VII. Effect of Various Treatments on Prolactin Activity

VIII. Topographical Location of Functional (Exposed) Residues by Reactions with Specific Reagents

IX. Reaction with 2-(2-Nitrophenylsulfenyl)-3-Methyl-3-Bromoindoleamine (BNPS-Skatole)

X. Two Fragments from Fibrinolysis Digests and Their Recombination to Generate Full Immunoreactivity

XI. Synthesis of Ovine Prolactin Fragments

XII. Isolation and Properties of Fish Prolactin

XIII. Concluding Remarks


2 The Role of Prolactin in Normal Mammary Gland Growth and Function

I. Introduction

II. Hormonal Requirements

III. Effect of Prolactin on Lactogenesis in Organ Culture

IV. Mechanism of Action of Prolactin

V. Effect of Hormones on Growth in Organ Culture

VI. Concluding Remarks


3 Mammotropin Effects in Tumor Induction and Growth

I. Introduction

II. Mammotropin: Nature and Origin

III. Mammotropin and Mammary Cancer

IV. Mammotropin and Other Neoplasms

V. Concluding Remarks


4 Comparative Endocrinology of Prolactin

I. Introduction

II. Cellular Origin of Prolactin

III. Reproductive Effects

IV. Effect of Prolactin on Structures Relating to Care of Young

V. Prolactin and Osmoregulation

VI. Growth and Differentiation

VII. Metabolic Actions

VIII. Behavioral Effects

IX. Miscellaneous Effects of Prolactin

X. Interaction of Prolactin with Other Hormones

XI. Control of Prolactin Secretion

XII. Evolution of Prolactin

XIII. Concluding Remarks

XIV. Addendum


5 Reflections on the Life and Works of F.L. Hisaw and H.B. van Dyke: Two Pioneers in Research on the Reproductive Hormones

I. Introduction

II. Frederick Lee Hisaw

III. Harry Benjamin van Dyke




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© Academic Press 1980
28th June 1980
Academic Press
eBook ISBN:

About the Editor

Choh Hao Li

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