1st Edition - June 28, 1980

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  • Editor: Choh Hao Li
  • eBook ISBN: 9780323159258

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Hormonal Proteins and Peptides: Prolactin, Volume VIII focuses on the broad spectrum of biological activities of prolactin among the vertebrates. This book discusses the function of prolactin in stimulating crop milk formation in birds as well as in inducing incubation behavior in the ring dove. Organized into five chapters, this volume starts with an overview of the chemistry of prolactin and its role on normal mammary gland growth and function. This text then explores the prolactin effects in tumor induction and growth. Other chapters review the status of the evolutionary biology and comparative endocrinology of prolactin. This book discusses as well the nature of prolactin cells, the control of prolactin secretion, and the nature of the prolactins from various vertebrate sources. The final chapter considers the significant advances in gonadotropins, including prolactin, follitropin, relaxin, and lutropin. This book is a valuable resource for biologists, endocrinologists, zoologists, embryologists, physicians, and medical health professionals.

Table of Contents

  • List of Contributors


    Contents of Previous Volumes

    1 The Chemistry of Prolactin

    I. Introduction

    II. Isolation Procedures

    III. Characterization of Ovine and Porcine Prolactin

    IV. Alkaline Titration by CD and Fluorescence in Comparison with HGH and HCS

    V. Immunochemical Properties

    VI. Primary Structure

    VII. Effect of Various Treatments on Prolactin Activity

    VIII. Topographical Location of Functional (Exposed) Residues by Reactions with Specific Reagents

    IX. Reaction with 2-(2-Nitrophenylsulfenyl)-3-Methyl-3-Bromoindoleamine (BNPS-Skatole)

    X. Two Fragments from Fibrinolysis Digests and Their Recombination to Generate Full Immunoreactivity

    XI. Synthesis of Ovine Prolactin Fragments

    XII. Isolation and Properties of Fish Prolactin

    XIII. Concluding Remarks


    2 The Role of Prolactin in Normal Mammary Gland Growth and Function

    I. Introduction

    II. Hormonal Requirements

    III. Effect of Prolactin on Lactogenesis in Organ Culture

    IV. Mechanism of Action of Prolactin

    V. Effect of Hormones on Growth in Organ Culture

    VI. Concluding Remarks


    3 Mammotropin Effects in Tumor Induction and Growth

    I. Introduction

    II. Mammotropin: Nature and Origin

    III. Mammotropin and Mammary Cancer

    IV. Mammotropin and Other Neoplasms

    V. Concluding Remarks


    4 Comparative Endocrinology of Prolactin

    I. Introduction

    II. Cellular Origin of Prolactin

    III. Reproductive Effects

    IV. Effect of Prolactin on Structures Relating to Care of Young

    V. Prolactin and Osmoregulation

    VI. Growth and Differentiation

    VII. Metabolic Actions

    VIII. Behavioral Effects

    IX. Miscellaneous Effects of Prolactin

    X. Interaction of Prolactin with Other Hormones

    XI. Control of Prolactin Secretion

    XII. Evolution of Prolactin

    XIII. Concluding Remarks

    XIV. Addendum


    5 Reflections on the Life and Works of F.L. Hisaw and H.B. van Dyke: Two Pioneers in Research on the Reproductive Hormones

    I. Introduction

    II. Frederick Lee Hisaw

    III. Harry Benjamin van Dyke



Product details

  • No. of pages: 246
  • Language: English
  • Copyright: © Academic Press 1980
  • Published: June 28, 1980
  • Imprint: Academic Press
  • eBook ISBN: 9780323159258

About the Editor

Choh Hao Li

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