Prolactin Secretion: A Multidisciplinary Approach - 1st Edition - ISBN: 9780124906204, 9780323141277

Prolactin Secretion: A Multidisciplinary Approach

1st Edition

Editors: Flavio Mena
eBook ISBN: 9780323141277
Imprint: Academic Press
Published Date: 1st January 1984
Page Count: 450
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Prolactin Secretion: A Multidisciplinary Approach covers the proceedings of the 1982 symposium on the frontiers and perspective of prolactin secretion through a multidisciplinary approach, convened in Nabor Carrillo Hall of the Natural University of Mexico. The symposium represents a genuine interdisciplinary effort to provide insights into the complexities of prolactin. Separating 24 manuscripts into chapters, this book first discusses studies on the molecular evolution of prolactin (PRL) and the related growth hormones and placental lactogens and the relevance of these studies for biological research on PRL, with particular emphasis on PRL secretion. Significant topics on the physiology, biochemistry, synthesis regulation, structure, function, glycoconjugates, gene expression control, regulatory, and control mechanisms of PRL and its secretion are considered in the subsequent chapters. This book also examines the action(s) of dopamine on the PRL-producing cells, the effects of his-pro diketopiperazine on PRL secretion, and the role of cellular phospholipids and the Ca2+-calmodulin system as modulators of PRL release. The effect of the suckling stimulus on the induction of PRL release in different reproductive states and the role of PRL in parental behavior in selected species of mammals and birds are also considered. The concluding chapters describe the morphologic features of abnormal lactotrophs, the in vivo and in vitro secretory activity exhibited by different types of pituitary adenomas and hyperprolactinemia. This book serves as an important reference for a wide range of investigators and advanced medical students who are engaged in the study of basic and clinical prolactin physiology.

Table of Contents




The Molecular Evolution of Prolactin and Related Hormones

Comparative Physiology of the Prolactin Cell

The Biochemistry and Physiology of Mouse Placental Lactogen

The Effect of Maternal-Fetal Interactions on Prolactin Secretion

Regulation of the Synthesis and Release of Decidual Prolactin

The Prolactin Cell: Structure and Function

Extracellular Glycoconjugates and Prolactin Secretion

Studies on the Control of Prolactin Gene Expression by Calcium and Hormones

Estrogen Effects on Prolactin Storage and Cell Growth in GH Cells

Molecular Mechanism of Prolactin Release from Pituitary Secretory Granules

Regulatory and Control Mechanisms of Prolactin Secretion Within the Pituitary of the Lactating Rat

Transduction of Dopamine and Vasoactive Intestinal Polypeptide Signals in Prolactin-Secreting Cells

Electrophysiological Approach of Stimulus-Secretion Coupling in Prolactin-Secreting Cells

Characterization of Anterior Pituitary Dopamine Receptors

Metabolism of Thyrotropin Releasing Hormone and Its Possible Relevance to Prolactin Secretion

On the Intracellular Mechanisms That Regulate Prolactin Secretion

Interaction of Estrogens with Dopamine and Calcium in the Regulation of Prolactin Release In Vivo

Control of the Multiphase Secretion of Prolactin in the Lactating Rat

Relationship Between Depletion and Release of Prolactin in the Lactating Rat: A Quantitative Analysis

Suckling-Induced Release of Prolactin in Nonlactating Rats

Prolactin and Parental Behavior Among Selected Species of Mammals and Birds

The Morphology of Abnormal Lactotrophs

Morphofunctional Analysis of Hormonal Secretion in Pituitary Neoplasia

Neuroendocrine Studies of Prolactin Secretion in Hyperprolactinemic States

Concluding Remarks



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© Academic Press 1984
Academic Press
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About the Editor

Flavio Mena

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