Progress in Theoretical Biology

Progress in Theoretical Biology

Volume 1

1st Edition - January 1, 1967

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  • Editor: Fred M. Snell
  • eBook ISBN: 9781483224978

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Progress in Theoretical Biology, Volume 1 brings together the significant and timely theoretical developments in particular areas of biology. Topics range from chemical evolution and biological self-replicating systems to quantitative aspects of goal-seeking self-organizing systems. An essay on Erwin Schrödinger (1887-1961) and his work on genetics and quantum mechanics, as well as its influence on molecular biology, is also included. Comprised of five chapters, this volume first discusses chemical evolution in terms of organic geochemistry and prebiotic chemistry. Dehydration condensation reactions as well as the generation of order and new information are also considered. The next chapter deals with biological self-replicating systems and focuses on such topics as the minimum system capable of self-replication; the minimum system capable of self-replication in terms of the generalizations of terrestrial biology; and which biological systems most nearly approach this limiting behavior. A series of definitions that provide a framework for examining minimal reproducing systems are also presented. The final three chapters explore the quantitative aspects of goal-seeking self-organizing systems; statistical thermodynamics of polymerization and polymorphism of proteins; and the importance of models in theoretical biology. This book is intended for both biological and physical scientists.

Table of Contents

  • List of Contributors


    Erwin Schrödinger

    Chemical Evolution

    I. Introduction

    II. Organic Geochemistry

    III. Prebiotic Chemistry

    IV. Dehydration Condensation Reactions

    V. Generation of Order and New Information

    VI. Conclusion


    Biological Self-Replicating Systems

    I. Introduction and Definitions

    II. Limits and Constraints on Self-Replicating Entities

    III. Universal Features Characterizing Living Systems

    IV. The Theoretical Minimum Cell


    Quantitative Aspects of Goal-Seeking Self-Organizing Systems

    I. Constraints versus Requirements

    II. Quantitative Aspects of the Genetic System


    Statistical Thermodynamics of Polymerization and Polymorphism of Protein


    I. Polymerization as Crystallization

    II. Two States of Monomers and One Type of Polymer

    III. Two Types of Polymers

    IV. Polymers Composed of Two Kinds of Monomers

    V. Effect of Nucleus

    VI. Kinetic Analysis

    VII. Comparison with Experiment

    VIII. Concluding Remarks


    The Role of Models in Theoretical Biology

    I. Models of Biological Systems

    II. Mathematical Modeling Theory

    III. Physical Analogs of Organisms

    IV. Artificial Organs

    V. Numerical and Kinetic Models

    VI. Cybernetic Models

    VII. Simulation of Physiological Regulation

    VIII. Neurophysiological Models

    IX. Artificial Intelligence and Algorithmic Models of Thought

    X. Self-Organizing Systems and Bionics

    XI. Abstract and Axiomatic Models

    XII. The Role of Biological Modeling


    Author Index

    Subject Index

Product details

  • No. of pages: 244
  • Language: English
  • Copyright: © Academic Press 1967
  • Published: January 1, 1967
  • Imprint: Academic Press
  • eBook ISBN: 9781483224978

About the Editor

Fred M. Snell

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