Progress in Theoretical Biology

Progress in Theoretical Biology

Volume 5

1st Edition - January 1, 1978

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  • Editors: Robert Rosen, Fred M. Snell
  • eBook ISBN: 9781483219295

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Progress in Theoretical Biology, Volume 5 covers the developments in theoretical biology. The book discusses the dynamic behaviors exhibited by cellular control circuits and the role of the cell as a morphogenetic and physiological unit; the stable dynamics of genetic networks; and the organization principles and models of the function of the simplest genetic systems controlling ontogenesis. The text also describes the conceptual framework shifts in immunogenetics: the anatomy of the Ag system; the basic problems of memory in behavioural and developmental biology; and the self-organization and performance of sensory-motor codes, maps, and plans. Physiologists, biophysicists, geneticists, mathematicians, and cytologists will find the book useful.

Table of Contents

  • Contributors


    Contents of Previous Volumes

    The Dynamics of Feedback Control Circuits in Biochemical Pathways

    I. Introduction

    II. Kinetic Equations

    III. Inducible Systems

    IV. Repressible Systems

    V. Discussion


    Stable Dynamics of Genetic Networks

    I. Introduction

    II. Connectance and Forcing Connectance

    III. Connection between Forcible Functions and Internal Homogeneity

    IV. Distribution of Number of Forcible Inputs among Boolean Functions

    V. Density of Noncontractible Functions

    VI. Metrics for Natural Boolean Order

    VII. Upper Bound on Forcing Connectance

    VIII. Large, Growing, Sparsely Connected Genetic Networks Condense and Have Largest Forcing Components

    IX. Joint Distribution of Cycle and Disclosure Length

    X. Distribution of Cycle and Disclosure Length: Predicted and Observed Effect of Forcibility

    XI. Genetic and Metabolic Implications


    Simplest Genetic Systems Controlling Ontogenesis: Organization Principles and Models of Their Function

    I. Simulation of the System Controlling λ Phage Development

    II. Some General Principles of the Organization of Bacteriophage Ontogenetic Systems

    II. Kinetic Equations

    III. Epigenes


    Conceptual Framework Shifts in Immunogenetics: The Anatomy of the Ag System

    I. Introduction

    II. Materials and Methods

    III. Complex-Simple Labeling of Sample Categories

    IV. Labeling of Group II Sample Categories

    V. Complex-Simple Restrictions

    VI. Some Simple-Complex Pseudo-Mysteries

    VII. Predictive Power of the New Framework

    VIII. The Structure of Serology

    IX. Summary and Conclusions


    Communication, Memory, and Development

    I. Introduction

    II. Between the Devil and the Deep Blue Sea: Noise versus Saturation

    III. The Statistics of Switches: Gain Control and Adaptation in On-Center Off-Surround Networks

    IV. Contrast Enhancement and Short-Term Memory

    V. The Statistics of Messages: Randomness Prevents Randomness

    VI. Competitive Group Interactions

    VII. Hysteresis, Peak Shifts, and Slow Drifts

    VIII. Ratio Processing by Antagonistic Cells

    IX. Slow Waves and Pacemakers

    X. Long-Term Memory

    XI. Reaction-Diffusion Models in Development

    XII. Regeneration of Hydra's Heads

    XIII. The Analogy between Regulation and Adaptation

    XIV. Blastula to Gastrula in the Sea Urchin

    XV. Pseudopodal Signaling and Self-Corrective Feedback

    XVI. Some Experimental Tests

    XVII. Production versus Directed Growth

    XVIII. Biochemical Memory and the Folds of Rhodnius

    XIX. Slime Mold Aggregation and Slug Motion

    XX. Adhesiveness, Growth, Cell Streaming, and Division

    XXI. Chemical Substrates of STM and LTM: Cyclic Nucleotides, Ions, Transmitters, and Protein Synthesis


    A Theory of Human Memory: Self-Organization and Performance of Sensory-Motor Codes, Maps, and Plans

    1. Introduction

    2. Stimulus Sampling of Spatial Patterns

    3. Sensory Codes and Motor Synergies

    4. Ritualistic Learning of Arbitrary Acts

    5. Nonspecific Arousal as a Command

    6. Self-Organization of Codes and Order Information

    7. Instrumental Conditioning

    8. STM Reverberation until Reward Influences LTM

    9. Rehearsal Resets STM Order Information Using Feedback Inhibition and Decouples Order and Velocity Information

    10. An Emergent Neocortical Analog

    11. Control of Performance Duration by STM and Arousal

    12. Serial Learning and STM → LTM Order Reversal

    13. Storing Spatial Patterns in STM

    14. Gain Control and Adaptation in On-Center Off-Surround Networks

    15. Contrast Enhancement in STM

    16. Tuning of STM and Releasing Subliminal Maps by Arousal

    17. Adaptive Coding and the Emergence of Command Chunks

    18. Feature Detectors

    19. Development of an STM Code

    20. Stabilizing the STM Code: Expectation, Resonance, Rebound, and Search

    21. Pattern Completion, Hysteresis, and Gestalt Switching

    22. Context-Dependent Coding and Restricted Conditions for Receding

    23. Reset, Reaction Time, and P300

    24. Hierarchical Critical Periods and Retrograde Amnesia

    25. Invariance of the Past Code under Future Sequential Inputs

    26. Bowing of the STM Pattern

    27. Regulation of STM Primacy, Recency, and Bowing by Lateral Inhibition

    28. Feedback Inhibition by Rehearsal in an Opaque STM Field

    29. Transient Memory Span and Free Recall

    30. Parallel versus Serial Search in STM

    31. The Influence of Rehearsal on Chunking

    32. Immediate Memory Span, and Readout of LTM Order Information by Feedback Signals from Commands

    33. A Minimal Model of Structural versus Transient Components of Memory

    34. Prediction

    35. Sensory Feedback and Interference by Its Delay

    36. Greater Weight and Longer Duration of Higher-Order Chunks

    37. Spatio-temporal Self-Similarity and the Resolution of Uncertainty

    38. Order-Preservation in the Future Field of Motor Commands

    39. Masking of STM by More Cell Sites or Amplified Signals

    40. STM Drift toward a Norm: Primary Gradient Induces Secondary Gradient

    41. Masking of Lower-Order Codes

    42. Clustering, Compression, Spacing, and Completion

    43. The Magic Number Seven and Self-Similar Coding

    44. Suppression of Uniform Patterns and Edge Detection

    45. The Growth of On-Center Off-Surround Connections

    46. Goal Gradient and Plans

    47. STM Order Reversal: Item Learning versus Order Learning

    48. Circular Reaction and Map Formation

    49. Quenching of Irrelevant Cues

    50. Feedforward Reset of Sequential Terminal Maps

    51. Posture, Isometrics, Saccades, and Feedforward Motor Control

    52. Feedforward versus Feedback Control of Sequential Map Performance

    53. Sequential Switching between Sensory and Motor Maps

    54. Map Reversal by Antagonistic Rebound

    55. Imprinting, Imitation, and Sensory–Motor Algebra

    56. Self-Tuning and Multidimensional Inference in a Parallel Processor

    57. No Sensory Feedback Implies No Map Formation

    58. Does the Psychophysical Power Law Influence Imitation Errors?

    59. Rhythm and Phrasing

    60. Reciprocal Intermodality Feedback, Internal Hearing, and Naming

    61. Automatic versus Controlled Information Processing

    62. Visual versus Auditory Processing and Cerebral Dominance

    63. Concluding Remarks: Universal Adaptive Measurement

    Subject Index

Product details

  • No. of pages: 392
  • Language: English
  • Copyright: © Academic Press 1978
  • Published: January 1, 1978
  • Imprint: Academic Press
  • eBook ISBN: 9781483219295

About the Editors

Robert Rosen

Fred M. Snell

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