Progress in Medicinal Chemistry - 1st Edition - ISBN: 9780444894724, 9780080862774

Progress in Medicinal Chemistry, Volume 29

1st Edition

Serial Editors: G. P. Ellis D.K. Luscombe
eBook ISBN: 9780080862774
Imprint: Elsevier Science
Published Date: 2nd March 1992
Page Count: 349
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The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT 3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey of the herb feverfew. The volume concludes, as it began, with enzyme inhibition - in this case concerning synthetic inhibitors of interstitial collagenases.


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© Elsevier Science 1992
Elsevier Science
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About the Serial Editors

G. P. Ellis Serial Editor

Affiliations and Expertise

Department of Chemistry, University of Wales Institute of Science and Technology. King Edward VII Avenue, Cardiff

D.K. Luscombe Serial Editor

Affiliations and Expertise

Welsh School of Pharmacy, University of Wales