Progress in Chemical Toxicology

Progress in Chemical Toxicology, Volume 3 explores the developments in methods and instrumentation for toxicological analyses. This book is composed of eight chapters, and begins with a description of the pharmacologic and physiologic effects of aliphatic alcohols. The succeeding chapter deals with the methods of analysis of various volatile poisons, such as halogenated aliphatic compounds, aromatic hydrocarbons, and acid compounds. A chapter focuses on the methods of determination and classic procedures for carbon monoxide analysis in breath and blood. These topics are followed by discussions on the development of spectrochemical methods chemical and radiochemical methods of determination of radionuclides in human bones and tissues; and the toxic effects of combined drug action. The last chapter examines the poison residue occurrence in human tissues. This book is of great value to toxicologists and public health workers and researchers.

Contributors Preface Contents of Other Volumes Aliphatic Alcohols I. Introduction II. "Endogenous" Alcohols III. Distribution of Absorbed Alcohol IV. Fate of Absorbed Alcohol V. Pharmacological and Physiological Effects VI. Post-mortem Changes in Cadaver Blood VII. Analytical Methods for Body Alcohol VIII. Investigations of the Accuracy of Analytical Methods IX. Other Aliphatic Alcohols References Volatile Toxic Compounds I. Introduction II. Halogenated Aliphatic Compounds III. Aromatic Hydrocarbons IV. Volatile Acidic Compounds References Methods for the Determination of Carbon Monoxide I. Introduction II. Preparation of Carbon Monoxide Standard Mixtures III. Collection of Air and Breath Samples IV. Analysis of Air and Breath Samples V. Analysis of Blood Samples References Application of Gas Chromatography to Toxicology I. Introduction II. Detectors III. Columns IV. Qualitative Techniques V. Analytical Procedures References Developments in Spectrography: Spectrochemical Methods I. Introduction II. Equipment and Materials III. Procedures References Detection of Radionuclides of Biological Interest in Human Bones and Tissues I. Introduction II. Chemical Processing and Separation of Radionuclides in Biological Material III. Chemical Separation and Determination of Radionuclides IV. Radiochemical Determination of Strontium-90 and Strontium-89 V. Radiochemical Determination of Cesium-137 VI. Radiochemical Determination of Iodine-131 VII. Radiochemical Determination of Radium-226 VIII. Thorium (Thorotrast) IX. Radiochemical Determination of Uranium X. Radiochemical Determination of Plutonium-239 XI. Instrumentation XII. Results of Measurements References Combined Action of Drugs with Toxicological Impl