Progress in Chemical Toxicology - 1st Edition - ISBN: 9780125365055, 9781483219240

Progress in Chemical Toxicology

1st Edition

Volume 5

Editors: Abraham Stolman
eBook ISBN: 9781483219240
Imprint: Academic Press
Published Date: 1st January 1974
Page Count: 406
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Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.

Table of Contents

Contents Contributors Preface Contents of Other Volumes The Absorption, Distribution, and Excretion of Drugs and Poisons and their Metabolites I. Gases and Vapors (Poisons through Inhalation) II. Volatile Liquids (Steam Distillation) III. Drugs Extractable by Organic Solvents from Aqueous Alkaline Solutions IV. Marijuana References A System for the Toxicological Analysis of Drugs in Biological Specimens I. Introduction II. Procedure for Analysis of Tissue III. Discussion IV. Simplified Wallace Procedure for the Identification of Drugs V. Analysis of Urine Samples for Drugs VI. Determination of Total Morphine in Urine References The Phenothiazines I. Introduction II. Materials III. Metabolites IV. Spectrofluorometry V. UV Spectrophotometry VI. Thin-Layer Chromatography VII. Color Reactions VIII. Gastric Contents IX. Soft Tissues X. Interference from the Presence of Other Drugs XI. Phenothiazine Levels in Blood Serum and Urine XII. Summary References Fluorescence in Toxicology I. Introduction II. Fundamentals of Fluorescence Analysis III. Theoretical Aspects of Fluorescence IV. Practical Aspects of Fluorescence V. Applications of Spectrophotofluorometry in Toxicology References Toxicology of New Synthetic Organic Polymers Used in Containers for Food, Pharmaceutical Compounds, and Drinkable Water I. Introduction II. Admission Procedure for a Formula III. Discussion and Justification of the Chemical Analytical Examination IV. General Review of the Testing Methods Applied to the Extraction and Stagnation Liquids V. Conclusion References Some Microcrystal Tests for Drugs I. Introduction II. Apparatus III. Reagents IV. Techniques V. Sample Preparation VI. Remarks Concerning the Tables References


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© Academic Press 1974
Academic Press
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About the Editor

Abraham Stolman

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