Progress in Chemical Toxicology - 1st Edition - ISBN: 9780125365055, 9781483219240

Progress in Chemical Toxicology

1st Edition

Volume 5

Editors: Abraham Stolman
eBook ISBN: 9781483219240
Imprint: Academic Press
Published Date: 1st January 1974
Page Count: 406
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Description

Progress in Chemical Toxicology, Volume 5 covers topics on the improved isolation and detection procedures and quantitation methods for volatile poisons, stimulants, hallucinogenic drugs, and marihuana. The book discusses the absorption, distribution, and excretion of drugs and poisons and their metabolites; the system for the toxicological analysis of drugs in biological specimens; and the isolation and analysis of phenothiazines. The text also describes the use of fluorescence in toxicology and the toxicology of new synthetic organic polymers used in containers for food, pharmaceutical compounds, and drinkable water. Some microcrystal tests for drugs and advances in polarography as applied to toxicological analysis are also considered. Biochemists, toxicologists, and scientists involved in the study of narcotics will find the book invaluable.

Table of Contents


Contents

Contributors

Preface

Contents of Other Volumes

The Absorption, Distribution, and Excretion of Drugs and Poisons and their Metabolites

I. Gases and Vapors (Poisons through Inhalation)

II. Volatile Liquids (Steam Distillation)

III. Drugs Extractable by Organic Solvents from Aqueous

Alkaline Solutions

IV. Marijuana

References

A System for the Toxicological Analysis of Drugs in Biological Specimens

I. Introduction

II. Procedure for Analysis of Tissue

III. Discussion

IV. Simplified Wallace Procedure for the Identification of Drugs

V. Analysis of Urine Samples for Drugs

VI. Determination of Total Morphine in Urine

References

The Phenothiazines

I. Introduction

II. Materials

III. Metabolites

IV. Spectrofluorometry

V. UV Spectrophotometry

VI. Thin-Layer Chromatography

VII. Color Reactions

VIII. Gastric Contents

IX. Soft Tissues

X. Interference from the Presence of Other Drugs

XI. Phenothiazine Levels in Blood Serum and Urine

XII. Summary

References

Fluorescence in Toxicology

I. Introduction

II. Fundamentals of Fluorescence Analysis

III. Theoretical Aspects of Fluorescence

IV. Practical Aspects of Fluorescence

V. Applications of Spectrophotofluorometry in Toxicology

References

Toxicology of New Synthetic Organic Polymers Used in Containers for Food, Pharmaceutical Compounds, and Drinkable Water

I. Introduction

II. Admission Procedure for a Formula

III. Discussion and Justification of the Chemical Analytical Examination

IV. General Review of the Testing Methods Applied to the Extraction and Stagnation Liquids

V. Conclusion

References

Some Microcrystal Tests for Drugs

I. Introduction

II. Apparatus

III. Reagents

IV. Techniques

V. Sample Preparation

VI. Remarks Concerning the Tables

References

Advances in Polarography as Applied to Toxicological Analysis

I. Introduction

II. Oscillographic Polarography

III. General Techniques for Alternating Current Polarography

IV. Application to Toxicological Analysis

References

Reviews

Subject Index


Details

No. of pages:
406
Language:
English
Copyright:
© Academic Press 1974
Published:
Imprint:
Academic Press
eBook ISBN:
9781483219240

About the Editor

Abraham Stolman