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Progress in Chemical Toxicology - 1st Edition - ISBN: 9780125365017, 9781483219226

Progress in Chemical Toxicology

1st Edition

Volume 1

Editor: Abraham Stolman
eBook ISBN: 9781483219226
Imprint: Academic Press
Published Date: 1st January 1963
Page Count: 448
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Progress in Chemical Toxicology, Volume 1 covers the developments in toxicology, including the usefulness of the developed techniques and methods with necessary modifications for toxicological studies. The book describes the isolation and separation techniques for the identification of poisons; the application of gas chromatograph to toxicology; and the pharmacological and toxicological effects aliphatic alcohols. The text also discusses the isolation, purification, identication, and the toxicology of acidic and neutral poisons, ataraxics and nonbarbiturate sedatives. The determination of antiarthritics, antihistamines, and thymoleptics; the physicochemical properties for the identification of narcotics and related bases; and the toxicity of air pollutants are also considered. The book further tackles the analytical methods for air pollutants; the occurrence, symptoms, and treatment of mushroom poisoning; and the toxic components of poisonous seeds and fruits poisonous seeds and fruits. Toxicologists, chemists, and scientists in forensic science laboratories will find the text invaluable.

Table of Contents


Isolation and Separation Techniques for Identification of Poisons

I. Acetone Extraction of Organic Substances

II. Separation of Alkaloids from Tissue

III. Two-Stage Extraction


Application of Gas Chromatography to Toxicology

I. Introduction

II. Columns

III. Detectors

IV. Carrier Gas

V. Sample

VI. Chromatogram Records

VII. Basic Theory

VIII. Analytical Procedures


Aliphatic Alcohols

I. Introduction

II. "Endogenous" Alcohol

III. Absorption of Alcohol

IV. Distribution of Absorbed Alcohol

V. Fate of Body Alcohol

VI. Pharmacological and Toxicological Effects

VII. Abnormal Changes in Alcohol Level

VIII. Medicolegal Interpretation of Blood Alcohol Level

IX. Analytical Methods for Body Alcohol

X. Investigations of the Accuracy of Analytical Methods

XI. Other Aliphatic Alcohols


Acidic and Neutral Poisons

I. Introduction

II. Isolation Procedures

III. Purification Procedures

IV. Identification

V. Analyses for Specific Poisons

VI. General Toxicology

VII. Conclusions


Ataraxics and Nonbarbiturate Sedatives

I. Introduction

II. Derivatives of Phenothiazine

III. d-Propoxyphene

IV. Chlordiazepoxide

V. Glutethimide

VI. Hydroxyzine

VII. Methapyrilene

VIII. Ethchlorvynol

IX. Methyprylon

X. Ethinamate

XI. Phenaglycodol

XII. Captodiamine

XIII. Imipramine


The Determination of Antiarthritics, Antihistamines, and Thymoleptics

I. Antiarthritics

II. Antihistamines

III. Thymoleptics


Narcotics and Related Bases

I. General Introduction

II. Literature Review

III. Physicochemical Methods for the Identification of Narcotics and Related Bases

IV. Opium—Assay, Characteristics, Composition, and Origin

V. Cannabis (Marijuana)


Toxicity of Air Pollutants

I. Introduction

II. Photochemical Smog

III. Effects of Photochemical Smog

IV. Toxicity of Air Pollutants


Analytical Methods for Air Pollutants

I. Introduction

II. Analysis of Pollutants Which May Have a Direct Toxic Effect if Present in the Atmosphere in Sufficient Concentration for a Sufficient Period of Time

III. Analysis of Pollutants Which May Not Be Present in the Atmosphere in Sufficient Concentration to Cause Toxicity but Which May Create Nuisance Problems Due to Odor

IV. Analysis of Pollutants Involved in the Photochemical Process

V. Continuous Automatic Measurement of Air Contaminants


Poisonous Mushrooms

I. Introduction

II. Chemistry and Methods of Detection of Mushroom Poisons

III. Symptoms and Treatment of Mushroom Poisoning

IV. Names, Descriptions, and Relative Toxicities of Poisonous Mushrooms


Poisonous Seeds and Fruits

I. Introduction

II. Definitions and Distinctions

III. Toxic Components

IV. Toxic Fruits and Seeds


Author Index

Subject Index


No. of pages:
© Academic Press 1963
1st January 1963
Academic Press
eBook ISBN:

About the Editor

Abraham Stolman

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