Progress in Chemical Toxicology

Progress in Chemical Toxicology

Volume 1

1st Edition - January 1, 1963

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  • Editor: Abraham Stolman
  • eBook ISBN: 9781483219226

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Progress in Chemical Toxicology, Volume 1 covers the developments in toxicology, including the usefulness of the developed techniques and methods with necessary modifications for toxicological studies. The book describes the isolation and separation techniques for the identification of poisons; the application of gas chromatograph to toxicology; and the pharmacological and toxicological effects aliphatic alcohols. The text also discusses the isolation, purification, identication, and the toxicology of acidic and neutral poisons, ataraxics and nonbarbiturate sedatives. The determination of antiarthritics, antihistamines, and thymoleptics; the physicochemical properties for the identification of narcotics and related bases; and the toxicity of air pollutants are also considered. The book further tackles the analytical methods for air pollutants; the occurrence, symptoms, and treatment of mushroom poisoning; and the toxic components of poisonous seeds and fruits poisonous seeds and fruits. Toxicologists, chemists, and scientists in forensic science laboratories will find the text invaluable.

Table of Contents

  • Contents

    Isolation and Separation Techniques for Identification of Poisons

    I. Acetone Extraction of Organic Substances

    II. Separation of Alkaloids from Tissue

    III. Two-Stage Extraction


    Application of Gas Chromatography to Toxicology

    I. Introduction

    II. Columns

    III. Detectors

    IV. Carrier Gas

    V. Sample

    VI. Chromatogram Records

    VII. Basic Theory

    VIII. Analytical Procedures


    Aliphatic Alcohols

    I. Introduction

    II. "Endogenous" Alcohol

    III. Absorption of Alcohol

    IV. Distribution of Absorbed Alcohol

    V. Fate of Body Alcohol

    VI. Pharmacological and Toxicological Effects

    VII. Abnormal Changes in Alcohol Level

    VIII. Medicolegal Interpretation of Blood Alcohol Level

    IX. Analytical Methods for Body Alcohol

    X. Investigations of the Accuracy of Analytical Methods

    XI. Other Aliphatic Alcohols


    Acidic and Neutral Poisons

    I. Introduction

    II. Isolation Procedures

    III. Purification Procedures

    IV. Identification

    V. Analyses for Specific Poisons

    VI. General Toxicology

    VII. Conclusions


    Ataraxics and Nonbarbiturate Sedatives

    I. Introduction

    II. Derivatives of Phenothiazine

    III. d-Propoxyphene

    IV. Chlordiazepoxide

    V. Glutethimide

    VI. Hydroxyzine

    VII. Methapyrilene

    VIII. Ethchlorvynol

    IX. Methyprylon

    X. Ethinamate

    XI. Phenaglycodol

    XII. Captodiamine

    XIII. Imipramine


    The Determination of Antiarthritics, Antihistamines, and Thymoleptics

    I. Antiarthritics

    II. Antihistamines

    III. Thymoleptics


    Narcotics and Related Bases

    I. General Introduction

    II. Literature Review

    III. Physicochemical Methods for the Identification of Narcotics and Related Bases

    IV. Opium—Assay, Characteristics, Composition, and Origin

    V. Cannabis (Marijuana)


    Toxicity of Air Pollutants

    I. Introduction

    II. Photochemical Smog

    III. Effects of Photochemical Smog

    IV. Toxicity of Air Pollutants


    Analytical Methods for Air Pollutants

    I. Introduction

    II. Analysis of Pollutants Which May Have a Direct Toxic Effect if Present in the Atmosphere in Sufficient Concentration for a Sufficient Period of Time

    III. Analysis of Pollutants Which May Not Be Present in the Atmosphere in Sufficient Concentration to Cause Toxicity but Which May Create Nuisance Problems Due to Odor

    IV. Analysis of Pollutants Involved in the Photochemical Process

    V. Continuous Automatic Measurement of Air Contaminants


    Poisonous Mushrooms

    I. Introduction

    II. Chemistry and Methods of Detection of Mushroom Poisons

    III. Symptoms and Treatment of Mushroom Poisoning

    IV. Names, Descriptions, and Relative Toxicities of Poisonous Mushrooms


    Poisonous Seeds and Fruits

    I. Introduction

    II. Definitions and Distinctions

    III. Toxic Components

    IV. Toxic Fruits and Seeds


    Author Index

    Subject Index

Product details

  • No. of pages: 448
  • Language: English
  • Copyright: © Academic Press 1963
  • Published: January 1, 1963
  • Imprint: Academic Press
  • eBook ISBN: 9781483219226

About the Editor

Abraham Stolman

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