Progress in Chemical Toxicology - 1st Edition - ISBN: 9780125365017, 9781483219226

Progress in Chemical Toxicology

1st Edition

Volume 1

Editors: Abraham Stolman
eBook ISBN: 9781483219226
Imprint: Academic Press
Published Date: 1st January 1963
Page Count: 448
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Progress in Chemical Toxicology, Volume 1 covers the developments in toxicology, including the usefulness of the developed techniques and methods with necessary modifications for toxicological studies. The book describes the isolation and separation techniques for the identification of poisons; the application of gas chromatograph to toxicology; and the pharmacological and toxicological effects aliphatic alcohols. The text also discusses the isolation, purification, identication, and the toxicology of acidic and neutral poisons, ataraxics and nonbarbiturate sedatives. The determination of antiarthritics, antihistamines, and thymoleptics; the physicochemical properties for the identification of narcotics and related bases; and the toxicity of air pollutants are also considered. The book further tackles the analytical methods for air pollutants; the occurrence, symptoms, and treatment of mushroom poisoning; and the toxic components of poisonous seeds and fruits poisonous seeds and fruits. Toxicologists, chemists, and scientists in forensic science laboratories will find the text invaluable.

Table of Contents

Contents Isolation and Separation Techniques for Identification of Poisons I. Acetone Extraction of Organic Substances II. Separation of Alkaloids from Tissue III. Two-Stage Extraction References Application of Gas Chromatography to Toxicology I. Introduction II. Columns III. Detectors IV. Carrier Gas V. Sample VI. Chromatogram Records VII. Basic Theory VIII. Analytical Procedures References Aliphatic Alcohols I. Introduction II. "Endogenous" Alcohol III. Absorption of Alcohol IV. Distribution of Absorbed Alcohol V. Fate of Body Alcohol VI. Pharmacological and Toxicological Effects VII. Abnormal Changes in Alcohol Level VIII. Medicolegal Interpretation of Blood Alcohol Level IX. Analytical Methods for Body Alcohol X. Investigations of the Accuracy of Analytical Methods XI. Other Aliphatic Alcohols References Acidic and Neutral Poisons I. Introduction II. Isolation Procedures III. Purification Procedures IV. Identification V. Analyses for Specific Poisons VI. General Toxicology VII. Conclusions References Ataraxics and Nonbarbiturate Sedatives I. Introduction II. Derivatives of Phenothiazine III. d-Propoxyphene IV. Chlordiazepoxide V. Glutethimide VI. Hydroxyzine VII. Methapyrilene VIII. Ethchlorvynol IX. Methyprylon X. Ethinamate XI. Phenaglycodol XII. Captodiamine XIII. Imipramine References The Determination of Antiarthritics, Antihistamines, and Thymoleptics I. Antiarthritics II. Antihistamines III. Thymoleptics References Narcotics and Related Bases I. General Introduction II. Literature Review III. Physicochemical Methods for the Identification of Narcotics and Related Bases IV. Opium—Assay, Characteristics, Composition, and Ori


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© Academic Press 1963
Academic Press
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About the Editor

Abraham Stolman

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