
Prognostic and Therapeutic Applications of RKIP in Cancer
Description
Key Features
- Provides an update from experts in the field on diagnostics, prognostics and therapeutics
- Brings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapter
- Provides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals
Readership
Table of Contents
1. RKIP: General Properties in Human MalignanciesInsight on the Role of RKIP in Cancer through Key Protein Partners and Cellular Protrusions
Francoise Schoentgen
2. Function of BACH1 as a key target of RKIP in Breast Cancer
Marsha Rich Rosner & Jiyoung Lee
3. Pleiotropic Activities of RKIP in Cancer: Role in Survival, EMT, Chemo-immuno-resistance, and Autophagy
Yuhao Wang & Benjamin Bonavida
4. Role of RKIP in the Tumor Response to Photo-oxidative Damage
Valentina Rapozzi & Luigi Emilio Xodo
5. A Review of RKIP Promotion of Tumour Progression, Metastasis and Poor Outcome in Multiple Solid Tumour Types
Sharon Glynn, Eoin Dervan, & Dibyangana Bhattacharyya
6. Tumor hypoxic stress, cellular plasticity and RKIP
Salem Chouaib, Stéphane Terry, Stéphanie Buart, & Abérémane Abdou
7. RKIP in Uterine Tissues
Pasquapina Ciarmela
8. The Role of RAF Kinase Inhibitor Protein in Hematologic Malignancies
Armin Zebisch
9. RKIP Regulation and Crosstalks Regulation of RKIP Expression in Breast Cancer Cells by miRNA
Kam Yeung, Julius Castro, Hussain N. Odeh, Christopher Figy, Miranda L. Yeung, & Robert Trumbly
10. The Master Cellular Regulators “RKIP & GSK3β”: Their Interactions and Repercussions on Cancer
Mira Bosso & Fahd Al-Mulla
11. Identification of Regulatory Crosstalks between RKIP and BCRA1 Tumor Suppressors in Healthy Tissues and Cancer (Breast and Ovarian): Therapeutic Implications
Martina Rama & Benjamin Bonavida
12. RKIP a Master of Regulatory Pathways: Perspectives
Khosrow Kashfi, Yongxin Zhou, & Gabrielle M. Corrente
13. Local and Systemic Endothelial Dysfunction in Cancer: RKIP-Mimetic, Therapy of Cancer and Endothelium-Safety
Marta Smeda, Marek Grosicki, & Stefan Chlopicki
14. Stochastic Modeling for Investigation of Regulation of Transcription of RKIP gene
Alexandre Ramos, Leonardo dos Reis Gama, Mauro César Cafundó Morais, & Poliana Cristina de Melo Martins
15. Anti-cancer effect of RKIP via modulating autophagy during metastasis
Deok Ryong Kim & Mahmoud Ahmed
16. RKIP and Inflammation The Role of Raf Kinase Inhibitory Protein in Inflammation
Steve Shenouda, Fahd Al-Mulla, Mira Bosso,& Rasheed Ahmad
17. Role of RKIP in inflammatory responses
Xiaojian Wang & Wenlong Lin
18. RKIP: Prognostic and Therapeutic Implications RKIP in Human Diseases and its Potential as a Prognostic Indicator and Therapeutic Target
Apostolos Zaravinos & Theodoulakis Christofi
19. Therapeutic Targeting of SNAIL, RKIP and YY1 in Tumor Metastasis and Drug Resistance
Nadire Özenver & Thomas Efferth
20. Implications of RKIP protein in cancer prognosis and therapy response: a literature update
Diana Cardoso-Carneiro, Ana Raquel-Cunha, Joana Pinheiro, Maria Gabriela-Freitas, Patrícia Fontão, Rui M. Reis, & Olga Martinho
21. Theranostic Role of RKIP in Cancer
Ganji Purnachandra Nagaraju, Begum Dariya, Gayathri Chalikonda, & Afroz Alam
22. Downregulation of the Raf Kinase Inhibitory Protein (RKIP) in Clear Cell Renal Cell Carcinoma Associates with Poor Prognosis
Damu Tang Anil Kapoor, Xiaozeng Lin, David Rodrig
Product details
- No. of pages: 504
- Language: English
- Copyright: © Academic Press 2020
- Published: February 3, 2020
- Imprint: Academic Press
- Hardcover ISBN: 9780128196120
- eBook ISBN: 9780128224519
About the Editors
Benjamin Bonavida
Affiliations and Expertise
Stavroula Baritaki
Affiliations and Expertise
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
Olga M. Mon Feb 10 2020
One of the best books ever in the cancer biology field
This is a wonderfulll and super complete book regarding an extremelly important protein in the cancer field , the RKIP. I completley reccomend this book.