Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

Key Features

- Presents comprehensive reviews covering all aspects of drug development and formulation of drugs - Now encompassing critical review chapters - Meets the information needs of the drug development community


Medicinal, pharmaceutical, and analytical chemists; pharmacologists.

Table of Contents

1. Acyclovir: Comprehensive Profile (Mochammad Yuwono, Gunawan Indrayanto).

2. Ceftriaxone Sodium: Comprehensive Profile (H.M. Owens, A.K. Dash).

3. Ipratropium Bromide (Heba H. Abdine et al.).
3.1 Physical Properties
3.2 Methods of Chemical and Biochemical Synthesis
3.3 Analytical Methods
3.4 Drug Metabolism and Pharmacokinetics

4. Ornidazole: Comprehensive Profile (Paramjeet Singh et al.).

5. Sertraline (L)-Lactate: Comprehensive Profile (M.D. Likar et al.).

6. Propylparaben: Physical Characteristics (Marcellino Rudyanto et al.).

7. X-ray Diffraction of Pharmaceutical Materials (H.G. Brittain).


No. of pages:
© 2003
Academic Press
Electronic ISBN:
Print ISBN:

About the serial-volume-editor

Harry Brittain

Center for Pharmaceutical Physics, Milford, NJ, USA