Principles of Nutrigenetics and Nutrigenomics

Principles of Nutrigenetics and Nutrigenomics is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from researchers around the world, the book covers how the genetic make-up influences the response to foods and nutrients and how nutrients affect gene expression. 

This book is broken into four parts providing a valuable overview of genetics,  nutrigenetics, and nutrigenomics, and a conclusion that will help translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields.

• Provides a uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics
• Includes a valuable guide to ethics for genetic testing for nutritional advice
• Provides definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts in each chapter
• Works together with a companion website that includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Researchers and students studying nutrition, genetics, genomics, personalized nutrition; clinicians including physicians, dieticians; food scientists and supplement pioneering personalized functional food and nutraceuticals product development

Section 1: The Biological Basis of Heritability and Diversity
1. The nature of traits, genes and variation
2. Epigenetic Mechanisms
3. Genotyping and sequencing
4. RNA analyses
5. Proteomic analyses
6. Metabolomic analyses
7. Epigenetics Methodology
8. Metagenomics
9. The role of nutrition in DNA damage and DNA repair
10. Study design in genetic epidemiology
11. Analytical methods in genetic epidemiology
12. Epistemology of nutrigenetic knowledge
13. Molecular biology of genetic variants

Section 2: Nutrigenetics
14. Genomics of Eating Behavior and Appetite Regulation
15. (14 BIS) Control of food intake and physiologic functions by food tastants through ectopic taste receptors
16. Energy
17. Carbohydrates
18. Protein metabolism
19. Amino Acids - Inborn Errors / Amino Acids - Polymorphic Variations in Metabolism
20. Monounsaturated and Saturated Fatty Acids
21. Omega-3 and omega-6 fatty acids
22. Cholesterol and plant sterols
23. Phytanic acid
24. Alcohol
25. Vitamin A and other carotenoids
26. Vitamin D
27. Vitamin E
28. Vitamin K
29. Vitamin C
30. Vitamin B2 (Riboflavin)
31. Niacin
32. Folate, vitamin B6, B12
33. Biotin and pantothenate
34. Choline
35. Electrolytes
36. Iron
37. Trace elements
38. Polyphenols
39. Caffeine
40. Epigenetics in food allergies: the missing piece of the puzzle
41. Genetic variations impacting the response to defined diets
42. Genetic variations in the response to weight-loss diets
43. Perinatal nutrition
44. Gut microbiota and their influence on the response to foods
45. Aging
46. Body composition, obesity and anorexia
47. Genetic variations in the response to exercise: impact on physical fitness and performance
48. Cognitive function
49. Hyperuricemia and gout
50. Cardiovascular disease
51. Hemostasis and thrombosi
52. Diabetes mellitus
53. Nutrigenetics of Cancer
54. Bone health
55. Psychiatric diseases
56. Genetics of Chrononutrition
57. Genetics of impact on immunocompetence
58. Nutrigenetics and the liver

Section 3: Nutrigenomics
59. Regulation of Gene Expression
60. Nutrients and gene expression in Obesity
61. Nutrients and gene expressio in Diabetes
62. Gene expression in dyslipemias
63. Nutrients and gene expression in Inflammation
64. Nutrients and gene expression in Cardiovascular Disease
65. Nutrients and Gene Expression in Cancer
66. Nutrients and Gene Expression Affecting Bone Metabolism
67. Nutrients and gene expression in developmental (in embroyonic and fetal development)
68. Methods in Nutrigenomics
69. A broader view on Omics and Systems Biology

Section 4: Traditional Nutrigentics and Nutrigenomics
70. When is the evidence sufficient for use in practice
71. Newborn Screening
72. Nutrigenetics-Based Intervention Studies
73. Genome-based nutrition guidance
74. Nutripharmacogentics
75. Food technology solutions
76. Setting genome-directed guidelines and algorithms
77. Direct-to-consumer services
78. Ethical considerations in nutrigenetics and nutrigenomics "
79. Privacy risks and protective measures
80. Legal frameworks in different countries
81. Impact of Nutrigenetics and Nutrigenomics on Society
82. Vitamins as Cofactors for Energy Homeostatsis and its Genetic Control