Principles of Heart Valve Engineering

Principles of Heart Valve Engineering

1st Edition - August 28, 2019

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  • Author: Arash Kheradvar
  • eBook ISBN: 9780128146620
  • Paperback ISBN: 9780128146613

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Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts.

Key Features

  • Covers the depth and breadth of this interdisciplinary area of research
  • Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering
  • Contains contributions from leading experts in the field that are heavily illustrated


Biomedical Engineers, Cardiologists, Cardiothoracic Surgeons, Cardiac Radiologists, R&D engineers at Heart Valve Companies, Scientists at FDA and other regulatory agencies, venture capitalists interested in funding early stage heart valve companies

Table of Contents

  • 1. Clinical Anatomy of Heart Valves
    2. Heart Valves' Mechanobiology
    3. Epidemiology of Heart Valve Disease
    4. Surgical Heart Valves
    5. Transcatheter Heart Valves
    6. Tissue Engineered Heart Valves
    7. Imaging Heart Valves
    8. Computational Modeling
    9. In Vitro Experimental Methods
    10. Transvalvular Flow
    11. Heart Valves' Leaflet Preparation
    12. Heart Valve Calcification
    13. Immunological Considerations
    14. Polymeric Heart Valves
    15. Regulatory Considerations

Product details

  • No. of pages: 414
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: August 28, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128146620
  • Paperback ISBN: 9780128146613

About the Author

Arash Kheradvar

Arash Kheradvar, M.D., Ph.D., FAHA is a Professor of Biomedical Engineering, Mechanical and Aerospace Engineering, and Medicine (Cardiology) at the University of California, Irvine. Dr. Kheradvar received M.D. from Tehran University of Medical Sciences in 2000 and Ph.D. in Bioengineering in 2006 from Caltech. His research interests are focused on heart valve engineering, cardiac fluid dynamics, and new cardiac imaging technologies. He is the author of two books and over 50 journal articles and the lead inventor of 45 issued and pending patents in cardiovascular area, mainly on heart valve technologies and imaging modalities. He is an elected Fellow to the American Heart Association by two councils of Cardiovascular Radiology and Intervention, and Cardiovascular Surgery and Anesthesia. Dr. Kheradvar founded KLAB, the Kheradvar research group, in 2007. The lab aims to study to the cardiovascular fundamental problems and devise translational solutions to ultimately help patients with cardiovascular disease by developing better diagnostic tools and more efficient therapeutic devices. KLAB is focused on research areas related to Heart Valve Engineering, Cardiovascular Imaging, and Cardiac Mechanics.

Affiliations and Expertise

Professor, Biomedical Engineering and Medicine (Cardiology), Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, CA, USA

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