Principles of Bone Biology

3rd Edition

Print ISBN: 9780123738844
eBook ISBN: 9780080568751
Imprint: Academic Press
Published Date: 29th September 2008
Page Count: 1900
360.00 + applicable tax
475.00 + applicable tax
290.00 + applicable tax
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Institutional Access


Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders.

Key Features

  • Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants…it is all in one source written by the experts in the field
  • The essential resource for anyone involved in the study of bones and bone diseases
  • Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics
  • Readers can easily search and locate information quickly as it will be online with this new edition


Academic and medical libraries as well as professionals in bone biology, endocrinology, and osteology

Table of Contents

Part I Basic Principles

A. Cell Biology

Chapter 1:
Structure, Modeling and Remodeling of Bone / The Size and Shape of Bone as a Site of Metabolic Bone Activity Ego Seeman

Chapter 2: Biomechanics of Bone Elise Morgan

Chapter 3: Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone Formation Andrew Karaplis

Chapter 4: Mesenchymal Stem Cells & Osteoblast Lineage Jane Aubin

Chapter 5: Transcriptional Control of Osteoblast Differentiation and Function Thorsten Schinke

Chapter 6: Wnt Signaling and Bone Mark Johnson

Chapter 7: Sclerostin and Bone Rutger van Bezooijen

Chapter 8: The Osteocyte Jenneke Klein-Nulend

Chapter 9: Cells of Bone: Osteoplast Generation Tatsuo Suda

Chapter 10: Osteoclast Function: Biology and Mechanisms Kalervo Vaananen

Chapter 11: RANK Signaling Hiroshi Takanayagi

Chapter12: Regulating Bone Resorption Roland Baron

Chapter 13: Apoptosis in Bone Cells Stavros Manolagas

Chapter 14: Skeletal Gene Expression in Nuclear Microenvironments Gary Stein

B. Biochemistry

Chapter 15: Type I Collagen: Structure, Synthesis, and Regulation Benoit de


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© Academic Press 2008
Academic Press
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Praise for the previous edition:
"Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine