Primer on Cerebrovascular Diseases is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, and presents the information in a comprehensive and easily accessible manner. The book also contains valuable information on practical applications of basic research.

Key Features

@introbul:Key Features @bul:* Presents topics in a comprehensive and accessible format * Written by international authorities on cerebral vasculature * Provides practical applications for researchers


Researchers, students, professionals in neuroscience, neurology, pharmacology, physiology, and biophysics.

Table of Contents

Cerebral Blood Flow, Don Reis. L. Sokoloff, Anatomy: Arterial Innervation, Cerebral Veins, and Microcirculation. G.J. del Zoppo, Embryogenesis and Angiogenesis. G. Feurerstein and A. Miller, Vasoactive Mediators of Cerebral Vessels. F.M. Faraci and D. Heistad, Biology of Cerebral Vascular Muscle. P.A. Stewart, Glial-Vascular Relations. W. Pardridge, Transport Mechanism. S.I. Rapoport, Brain Edema and the Blood-Brain Barrier. G.A. Rosenberg, CSF: Formation, Absorption, Markers and Relationship to Blood-Brain Barrier. C. Iadecola, Principles and Methods for Measurement of Cerebral Blood Flow. J. Mazziotta, M. Cohen, and A. Toga, The Measurement of Cerebral Blood Flow and Metabolism in Human Subjects. P.D. Hurm and R. Traystman, Overview of Cerebrovascular Hemodynamics. A.G. Hudetz, Cerebral Microcirculation. J-M. Chillon and G. Baumbach, Autoregulation of Cerebral Blood Flow. D. Traystman, Regulation of CBF by Carbon Dioxide. E. Golanov and D. Reis, Regulation of CBF by Hypoxia. L. Edvinsson and P.J. Goadsby, Extrinsic Innervation: Transmitters, Receptors and Functions--The Sympathetic Nervous System. P.J. Goadsby and L. Edvinsson, Extrinsic Innervation: Transmitters, Receptors and Functions--The Parasympathetic Nervous System. P.J. Goadsby and L. Edvinsson, Extrinsic Innervation: Transmitters, Receptors and Functions--the Trigeminovascular System. P. Magistretti, Coupling of Cerebral Blood Flow and Metabolism. U. Dirnagl and J. Dreier, Regulation of CBF by Ions21. H.R. Winn, Adenosine and


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© 1997
Academic Press
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About the editors

Louis R. Caplan

Dr. Louis R. Caplan, MD serves as Chief of Cerebrovascular and Stroke Division of Beth Israel Deaconess Medical Center. Dr. Caplan also serves as the Chief of the Stroke Service at the Beth Israel Deaconess Medical Center. He is a Professor of Neurology at Harvard Medical School, Boston.

Affiliations and Expertise

Chief Cardiovascular Diseases

Bo Siesjo

Affiliations and Expertise

Experimental Research Center, Lund University, Sweden

Bruce Weir

Affiliations and Expertise

Brain Surgery Research Institute, University of Chicago, Illinois, U.S.A.

Louis Caplan

Affiliations and Expertise

Tufts University School of Medicine, Boston, Massachusetts, U.S.A.

Donald Reis

Affiliations and Expertise

Cornell/New York Hospital, New York, U.S.A.


@qu:"The editors are outstanding figures in modern stroke science. This is an extremely comprehensive, high-quality primer composed of numerous short, well-edited, informative chapters written by notable authorities." @source:--Steven U. Brint, MD, University of Illinois at Chicago College of Medicine, for DOODY'S PUBLISHING REVIEWS