Presynaptic Receptors and Neuronal Transporters

1st Edition

Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990

Editors:

Description

Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.

Table of Contents

Preface Physiological and Pharmacological Relevance of Presynaptic Receptors in Neurotransmission Pre- and Postjunctional Muscarinic Receptors in the Guinea-Pig Trachea Presynaptic α-Autoadrenoceptors on Peripheral Noradrenergic Neurones of Newborn Rabbits and Dogs Cholinergic-Adrenergic Presynaptic Interactions in the Heart and Characterization of the Receptors Involved Structural Requirements for DA2 (Peripheral) Dopamine Receptor Agonist Activity α2-Adrenoceptor Modulation Or Noradrenaline Release in Human and Rabbit Renal Arteries: Clonidine Acts as a Partial Agonist Effect of α2-Adrenoceptor Antagonists on Norephine Release and Inhibition of Insulin Secretion During Pancreatic Nerve Stimulation. Interactions at Pre- and Postsynaptic Sites Antagonist Activity of Sl 84.0418 and Idazoxan at Pre and Post Synaptic α2-Adrenoreceptors Does the Distance Between Nerve Varicosities and Adrenoceptors Play Any Role in the Relative Contribution of Atp/Noradrenaline for Postjunctional Response? In Vivo Presynaptic Interaction Between 5-Ht and Adrenergic Antagonists on Noradrenergic Neurotransmission Activity of N-Ethyl-NOR-Arecaidine Propargyl Ester and (R)-Nipecotic Acid Ethyl Ester at Pre-and Postsynaptic Muscarinic Receptor Subtypes Effects of Neuromuscular Blocking Agents on Neuronal Nicotine Receptors of Motor Nerves: Blockade of Nicotinic Autofacilitation and Backfiring A Rapid In Vitro Assay of the Histaine H3-Receptor: Inhibition of Electrically Evoked Contractions of Guinea Pig Ileum Preparations Factors Influencing the Function of Presynaptic α2-Adrenoceptors in Rat Brain Presynaptic Dopaminergic Autoreceptors as Targets for Drugs Dopa Itself Facilitates Noradrenaline Release Via Presynaptic ß-Adrenoceptors in Rat Hypothalamic Slices - Dopa Is Probably a Neuroactive Substance The Third Dopamine Receptopr (D3) as an Autoreceptor Terminal Dopaminergic Autoreceptors are of Minor Importance for the Sedation Produced by DA Receptor Agonists in Rats Mo

Details

No. of pages:
372
Language:
English
Copyright:
© 1991
Published:
Imprint:
Pergamon
Electronic ISBN:
9781483278223
Print ISBN:
9780080411651

About the editors