Precision Medicine

Precision Medicine

1st Edition - August 23, 2022

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  • Editor: David Teplow
  • eBook ISBN: 9780323997850
  • Hardcover ISBN: 9780323997843

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Precision Medicine, Volume 190 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Evolution of Biomarkers and Strategies for Integrating the Precision Philosophy to Guide Monitoring of Individualized Autoimmunity Conditions and to Implement the Philosophy into Clinical Practice, Precision Medicine in Epilepsy, The use of ASOs for personized medicine, Adult medicine, EGFR, NF-KB signal and regulatory noncoding RNAs in cancer, Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis, The Paradox of Personalized Medicine, and more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Progress in Molecular Biology and Translational Science series
  • Updated release includes the latest information on the precision medicine


Academic, government and industrial sectors

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • Preface
  • Chapter One: Introduction of medical genomics and clinical informatics integration for p-Health care
  • Abstract
  • 1: Introduction
  • 2: State-of-the-art advanced data integration
  • 3: Case studies
  • 4: Privacy and security
  • 5: Conclusion
  • References
  • Chapter Two: Precision diagnostics in cancer: Predict, prevent, and personalize
  • Abstract
  • 1: Introduction
  • 2: NGS-based technologies
  • 3: Therapy selection
  • 4: Clinical trial design
  • 5: Conclusions
  • References
  • Chapter Three: Artificial intelligence and machine learning in precision medicine: A paradigm shift in big data analysis
  • Abstract
  • Highlights
  • 1: Introduction
  • 2: Artificial intelligence and big data: Changes in the landscape of precision healthcare and medicine
  • 3: The emergence of AI in precision medicine
  • 4: Synergies between artificial intelligence and precision medicine
  • 5: Promises of implementing AI/ML in healthcare
  • 6: The integration of nanomaterials in AI-based precision medicine
  • 7: The perspective of big data analytics in precision medicine
  • 8: AI and personalized medicine: A case of neurological disease
  • 9: Obstacles in translating big data into healthcare
  • 10: Opportunities for translating big data into healthcare
  • 11: Artificial intelligence and machine learning in precision medicine: An industry perspective
  • 12: Future challenges and perspectives of artificial intelligence in precision medicine
  • References
  • Chapter Four: Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis
  • Abstract
  • 1: Introduction
  • 2: Multi-omics strategies & precision medicine
  • 3: Deep phenotyping & precision medicine
  • 4: Discussion & future recommendations
  • References
  • Chapter Five: Progress in molecular biology and translational science addressing the needs of nano-rare patients
  • Abstract
  • 1: Introduction
  • 2: Parsing patient populations
  • 3: Mutation focused drug discovery
  • 4: Prerequisites to respond to the needs of nano-rare patients
  • 5: Creating an industrialized approach to the non-profit treatment of nano-rare patients
  • 6: The future
  • 7: Remaining challenges
  • References
  • Chapter Six: Precision medicine in epilepsy
  • Abstract
  • 1: Introduction
  • 2: Precision therapy in genetic epilepsy syndromes
  • 3: Precision therapy with personalized pharmacogenomics
  • 4: Precision therapy with neuromodulation
  • 5: Conclusion
  • References
  • Chapter Seven: EGFR, NF-κB and noncoding RNAs in precision medicine
  • Abstract
  • 1: Part 1: Epidermal growth factor receptor (EGFR)
  • 2: EGFR as a target in lung cancer treatment
  • 3: Acquired resistance of EGFR TKIs
  • 4: Precision medicine of EGFR in lung cancer
  • 5: Part 2: Nuclear factor-κappa B signaling
  • 6: NF-κB signaling pathway and its activation
  • 7: Part 3: Noncoding RNAs and EGFR in precision medicine
  • 8: Conclusion and future perspectives
  • References
  • Chapter Eight: Evolution of biomarker research in autoimmunity conditions for health professionals and clinical practice
  • Abstract
  • 1: Introductory
  • 2: Abs with catalytic activity (catAbs or abzymes)
  • 3: Progressing toward personalized and precision healthcare services and challenges in applying biomarkers for clinical autoimmunity conditions
  • 4: Specific autoimmunity conditions subareas
  • 5: Biomarkers in clinical practice: Biomarkers as applicable to personalized dietary protocols in autoimmune conditions
  • 6: Conclusion
  • References
  • Index

Product details

  • No. of pages: 296
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: August 23, 2022
  • Imprint: Academic Press
  • eBook ISBN: 9780323997850
  • Hardcover ISBN: 9780323997843

About the Editor

David Teplow

David Teplow
Professor Teplow is a member of the Department of Neurology, David Geffen School of Medicine at UCLA; Director, UCLA Biopolymer Laboratory; and a member of the faculties of the Molecular Biology Institute, Brain Research Institute, Chemistry-Biology Interface Training Program, and various neuroscience graduate programs. Professor Teplow received degrees in Biochemistry, and in Bacteriology & Immunology, from UC Berkeley; a Ph.D. from the University of Washington, Seattle; and postdoctoral training at the California Institute of Technology, Pasadena, CA. From 1991-2005, Professor Teplow was a member of the faculty of the Department of Neurology, Harvard Medical School, Boston. Professor Teplow has published >200 peer-reviewed articles, including ~150 original articles and ~50 reviews, book chapters, and commentaries. Professor Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology. He currently is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease. Professor Teplow is a member of numerous national and international scientific advisory and editorial boards.

Affiliations and Expertise

Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

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