Description

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more.

Key Features

  • Explores neuronal protection by polyphenol metabolites and their application to medical care
  • Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications
  • Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Readership

Nutritionists, dieticians, and clinical researchers interested in how the mechanisms of polyphenols contribute to the prevention and treatment of disease

Table of Contents

About the Editors

List of Contributors

Preface

Acknowledgments

Volume 1: Polyphenols in Chronic Diseases and their Mechanisms of Action

 

Section 1: Overview of Polyphenols and Health

Chapter 1. Polyphenols in Foods and Dietary Supplements: Role in Veterinary Medicine and Animal Health

1 Animal Models and Potential Medicinal Uses of Polyphenols

2 Companion Animals

3 Produce Animals

4 Conclusion

References

Chapter 2. Polyphenols and Public Health

1 Introduction

2 Polyphenol Content and Sources: Role in Health and Nutrition

3 Epidemiology of Polyphenols

4 Application of Polyphenols in Health Promotion

5 Governmental Regulations: Dietary Reference Intake

6 Concluding Remarks

References

Chapter 3. The History of Islamic Medicine at a Glance

1 Introduction

2 History of Islamic Medicine in the East Section of the Geographic Extent of the Islamic Civilization

3 History of Islamic Medicine in the West Section of the Geographic Extent of the Islamic Civilization

4 History of the Hospitals in the Islamic Civilization

Acknowledgments

References

Chapter 4. Polyphenols and Their Formulations: Different Strategies to Overcome the Drawbacks Associated with Their Poor Stability and Bioavailability

1 Introduction

2 Stability of Polyphenols: Formulation Approaches

3 Bioavailability of Polyphenols

4 Conclusions

References

Chapter 5. Biological Activities of Polyphenols from Grapes

1 Introduction

2 The Distribution and Occurrence of Different Types of Phenolic Compounds in Grape

3 Bioactivities of Phenolic Compounds from Grape

4 Bioavailability

5 Potential Toxicity

6 Conclusion

References

Chapter 6. The Atomic Level Interaction of Polyphenols wit

Details

No. of pages:
1488
Language:
English
Copyright:
© 2014
Published:
Imprint:
Academic Press
Electronic ISBN:
9780123984678
Print ISBN:
9780123984562

About the editors

Ronald Ross Watson

Ronald R. Watson, Ph.D., attended the University of Idaho but graduated from Brigham Young University in Provo, Utah, with a degree in chemistry in 1966. He earned his Ph.D. in biochemistry from Michigan State University in 1971. His postdoctoral schooling in nutrition and microbiology was completed at the Harvard School of Public Health, where he gained 2 years of postdoctoral research experience in immunology and nutrition. From 1973 to 1974 Dr. Watson was assistant professor of immunology and performed research at the University of Mississippi Medical Center in Jackson. He was assistant professor of microbiology and immunology at the Indiana University Medical School from 1974 to 1978 and associate professor at Purdue University in the Department of Food and Nutrition from 1978 to 1982. In 1982 Dr. Watson joined the faculty at the University of Arizona Health Sciences Center in the Department of Family and Community Medicine of the School of Medicine. He is currently professor of health promotion sciences in the Mel and Enid Zuckerman Arizona College of Public Health. Dr. Watson is a member of several national and international nutrition, immunology, cancer, and alcoholism research societies. Among his patents he has one on a dietary supplement; passion fruit peel extract with more pending. He continues to do research in animals and in clinical trials on dietary supplements and health including studies using omega-3 fatty acids in heart disease prevention and therapy. For 30 years he was funded by Wallace Research Foundation to study dietary supplements in health promotion. Dr. Watson has edited more than 110 books on nutrition, dietary supplements and over-the-counter agents, and drugs of abuse as scientific reference books. He has published more than 500 research and review articles.

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FSB, FRSH, FRIPH, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the multi-volume seminal work The Handbook Of Alcohol Related Pathology (published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.