Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

1st Edition - June 25, 2019

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  • Editors: Prashant Kesharwani, Kishore Paknikar, Virendra Gajbhiye
  • Paperback ISBN: 9780128169636
  • eBook ISBN: 9780128173312

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Description

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems.

Key Features

  • Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy
  • Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer
  • Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Readership

Research scientists and industry professionals in pharmaceutical science, biomedicine, polymer science, nanomedicine, cancer research and biotechnology who are working on technological advancement in designing targeted therapies and drug delivery systems

Table of Contents

  • Preface
    Prashant Kesharwani, Kishore M. Paknikar, Virendra Gajbhiye
    1. Current status and future challenges of various polymers as cancer therapeutics
    Pramod Kumar, Kavita Gajbhiye, Kishore M. Paknikar, Virendra Gajbhiye
    2. An overview of polymeric nanoparticles as potential cancer therapeutics
    Sankalp Agarwal, Abishai Dominic, Samiksha Wasnik
    3. Poly acrylate (e.g., poly methylacrylate, poly ethyl acrylate, etc.) nanoparticles as promising tool for anticancer therapeutics
    Kailash C. Petkar
    4. Poly (alkyl cyano acrylate) nanoparticles as promising tool for anticancer therapeutics
    Georgi Yordanov
    5. Poly (α-hydroxy acids) based nanoparticles for Drug/Gene delivery for cancer therapy
    Narsireddy Amreddy, Anish Babu, Anupama Munshi, Rajagopal Ramesh
    6. Poly (ester), Poly hydroxy alkanoate nanoparticles as promising tool for anticancer therapeutics
    Bapi Gorain, Hira Choudhury, Manisha Pandey, Chandrakanth Kokare, Prashant Kesharwani
    7. Poly (phospho ester), Poly (phosphazene) nanoparticles as promising tool for anticancer therapeutics
    Prajakta Tambe, Nida Sayed, Kishore M. Paknikar, Virendra Gajbhiye
    8. Poly (carbonate) nanoparticles as promising tool for anticancer therapeutics
    Sima Singh, Afzal Hussain, Rajeshwar Reddy Aleti, Manimbulu Nlooto, Rajshekhar Karpoormath
    9. Poly (amino acid) nanoparticles as promising tool for anticancer therapeutics
    Ahmed Elzoghby
    10. Poly ethylene glycol nanoparticles as promising tool for anticancer therapeutics
    Adityanarayan Mohapatra, Saji Uthaman, and In-Kyu Park
    11. Dendrimer (polyamidoamine, polypropylene imine, poly-L-lysine, carbosilane dendrimers, triazine dendrimers) as promising tool for anticancer therapeutics
    Rahul Shukla, Ajit Singh, Vishwas Pardhi, Sunil Dubey, Prashant Kesharwani
    12. Conjugated polymer nanoparticles as promising tool for anticancer therapeutics
    Sumithra Y. Srinivasan, Kavita Gajbhiye, Kishore M. Paknikar, Virendra Gajbhiye
    13. Microbes based natural polymer (Xanthum gum, alginate, gellan gum, carrageenan) nanoparticles as promising tool for anticancer therapeutics
    Vividha Dhapte, Varsha Pokharkar
    14. Plant based natural polymer (Guar gum, pectin, starch, cellulose, cyclodextrins) nanoparticles as promising tool for anticancer therapeutics
    Gamze Varan, Cem Varan, Erem Bilensoy
    15. Animal based natural polymer (Gelatin, chitosan, albumin, hyaluronic acid, chondroitin sulphate) nanoparticles as promising tool for anticancer therapeutics
    R. Jayachandra Babu, Manjusha Annaji, Ahmed Alsaqr, Robert D. Arnold
    16. Polymersomes as promising tool for anticancer therapeutics
    Mohammad Ramezani
    17. Other polymers (Poly sulfonic acids, Poly carboxylic acids, Poly boronic acid, Poly silamine, etc.) nanoparticles as promising tool for anticancer therapeutics
    Farah Rehan, Nafees Ahemad, Manish Gupta
    18. Conclusion and future prospective of polymeric nanoparticles as cancer therapeutics
    Rahul Shukla, Siva B. Lokesh, Mayank Handa, Prashant Kesharwani

Product details

  • No. of pages: 432
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: June 25, 2019
  • Imprint: Academic Press
  • Paperback ISBN: 9780128169636
  • eBook ISBN: 9780128173312

About the Editors

Prashant Kesharwani

Dr. Prashant Kesharwani is Assistant Professor of Pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has published more than 150 articles in well reputed international journals and edited 10 international books. Dr. Kesharwani has received several awards, including the ‘Ramanujan Fellowship, DST, India-2017’, ‘Excellence Research Award 2014’, ‘Young Innovator Award (Gold medal) 2012’, ‘International Travel Award/Grant from DST (New Delhi) and INSA (CCSTDS, Chennai) 2012’, as well as receiving an ICMR Senior Research Fellowship (PhD) and AICTE Junior Research Fellowship (M. Pharm.). He has presented invited talks and presentations at prestigious conferences, supervised students/junior researchers, and actively participated in outreach and scientific dissemination for the service of the wider community. Dr. Kesharwani’s current research is focused on the development of nano-engineered drug delivery systems for various diseases.

Affiliations and Expertise

Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India

Kishore Paknikar

Dr. Kishore M. Paknikar is Professor Agharkar Chair and former Director of Agharkar Research Institute, Pune, India. He is a MSc in Microbiology (1980) and a PhD in Microbiology (1984) from the University of Poona, India. His work in the field of delivery systems focuses on the delivery of drugs, proteins, peptides, siRNA, and nutrients. He is also exploring systems like polymeric nanoparticles and dendrimers for delivery of bioactive molecules in the treatment of cancers, Alzheimer’s disease, candidiasis, etc. He has more than 120 publications in highly reputed journals and 33 patents to his credit. He was a visiting Professor at Louis Pasteur University (Strasbourg, France) and Wayne State University (School of Medicine, Detroit, USA). He also worked as a Research Advisor at National Nanotechnology Centre (Ministry of Science and Technology), Bangkok, Thailand. He has several fellowships and awards to his credit.

Affiliations and Expertise

Professor Agharkar Chair, Agharkar Research Institute, Pune, India Visiting Professor, Indian Institute of Technology Bombay, Mumbai, India Visiting Professor, Malaviya National Institute of Technology, Jaipur, India

Virendra Gajbhiye

Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.

Affiliations and Expertise

Scientist in Nanomedicine, Agharkar Research Institute, Pune, India

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