Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

1st Edition - June 25, 2019
Editors: Prashant Kesharwani, Kishore M. Paknikar, Virendra Gajbhiye
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 1 6 9 6 3 - 6
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 3 3 1 - 2

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving… Read more

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

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Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers.

Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems.

PrefacePrashant Kesharwani, Kishore M. Paknikar, Virendra Gajbhiye1. Current status and future challenges of various polymers as cancer therapeuticsPramod Kumar, Kavita Gajbhiye, Kishore M. Paknikar, Virendra Gajbhiye2. An overview of polymeric nanoparticles as potential cancer therapeuticsSankalp Agarwal, Abishai Dominic, Samiksha Wasnik3. Poly acrylate (e.g., poly methylacrylate, poly ethyl acrylate, etc.) nanoparticles as promising tool for anticancer therapeuticsKailash C. Petkar4. Poly (alkyl cyano acrylate) nanoparticles as promising tool for anticancer therapeuticsGeorgi Yordanov5. Poly (α-hydroxy acids) based nanoparticles for Drug/Gene delivery for cancer therapyNarsireddy Amreddy, Anish Babu, Anupama Munshi, Rajagopal Ramesh6. Poly (ester), Poly hydroxy alkanoate nanoparticles as promising tool for anticancer therapeuticsBapi Gorain, Hira Choudhury, Manisha Pandey, Chandrakanth Kokare, Prashant Kesharwani7. Poly (phospho ester), Poly (phosphazene) nanoparticles as promising tool for anticancer therapeuticsPrajakta Tambe, Nida Sayed, Kishore M. Paknikar, Virendra Gajbhiye8. Poly (carbonate) nanoparticles as promising tool for anticancer therapeuticsSima Singh, Afzal Hussain, Rajeshwar Reddy Aleti, Manimbulu Nlooto, Rajshekhar Karpoormath9. Poly (amino acid) nanoparticles as promising tool for anticancer therapeuticsAhmed Elzoghby10. Poly ethylene glycol nanoparticles as promising tool for anticancer therapeuticsAdityanarayan Mohapatra, Saji Uthaman, and In-Kyu Park11. Dendrimer (polyamidoamine, polypropylene imine, poly-L-lysine, carbosilane dendrimers, triazine dendrimers) as promising tool for anticancer therapeuticsRahul Shukla, Ajit Singh, Vishwas Pardhi, Sunil Dubey, Prashant Kesharwani12. Conjugated polymer nanoparticles as promising tool for anticancer therapeuticsSumithra Y. Srinivasan, Kavita Gajbhiye, Kishore M. Paknikar, Virendra Gajbhiye 13. Microbes based natural polymer (Xanthum gum, alginate, gellan gum, carrageenan) nanoparticles as promising tool for anticancer therapeuticsVividha Dhapte, Varsha Pokharkar14. Plant based natural polymer (Guar gum, pectin, starch, cellulose, cyclodextrins) nanoparticles as promising tool for anticancer therapeuticsGamze Varan, Cem Varan, Erem Bilensoy15. Animal based natural polymer (Gelatin, chitosan, albumin, hyaluronic acid, chondroitin sulphate) nanoparticles as promising tool for anticancer therapeuticsR. Jayachandra Babu, Manjusha Annaji, Ahmed Alsaqr, Robert D. Arnold16. Polymersomes as promising tool for anticancer therapeuticsMohammad Ramezani17. Other polymers (Poly sulfonic acids, Poly carboxylic acids, Poly boronic acid, Poly silamine, etc.) nanoparticles as promising tool for anticancer therapeuticsFarah Rehan, Nafees Ahemad, Manish Gupta18. Conclusion and future prospective of polymeric nanoparticles as cancer therapeuticsRahul Shukla, Siva B. Lokesh, Mayank Handa, Prashant Kesharwani

Prashant Kesharwani

Dr. Prashant Kesharwani is working as an assistant professor of pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 300 international publications in well-reputed journals and more than 20 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also a receipt of several internationally acclaimed awards such as the most prestigious “Ramanujan Fellowship Award” from the Science and Engineering Research Board, Government of India. He actively participates in outreach and scientific dissemination for the service of the wider community.

Affiliations and expertise

Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India

Kishore M. Paknikar

Dr. Kishore M. Paknikar is Professor Agharkar Chair and former Director of Agharkar Research Institute, Pune, India. He is a MSc in Microbiology (1980) and a PhD in Microbiology (1984) from the University of Poona, India. His work in the field of delivery systems focuses on the delivery of drugs, proteins, peptides, siRNA, and nutrients. He is also exploring systems like polymeric nanoparticles and dendrimers for delivery of bioactive molecules in the treatment of cancers, Alzheimer’s disease, candidiasis, etc. He has more than 120 publications in highly reputed journals and 33 patents to his credit. He was a visiting Professor at Louis Pasteur University (Strasbourg, France) and Wayne State University (School of Medicine, Detroit, USA). He also worked as a Research Advisor at National Nanotechnology Centre (Ministry of Science and Technology), Bangkok, Thailand. He has several fellowships and awards to his credit.

Affiliations and expertise

Professor Agharkar Chair, Agharkar Research Institute, Pune, India Visiting Professor, Indian Institute of Technology Bombay, Mumbai, India Visiting Professor, Malaviya National Institute of Technology, Jaipur, India

Virendra Gajbhiye

Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.

Affiliations and expertise

Scientist in Nanomedicine, Agharkar Research Institute, Pune, India