Plotkin's Vaccines

Plotkin's Vaccines

7th Edition - April 7, 2017

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  • Authors: Walter Orenstein, Paul Offit, Kathryn M. Edwards, Stanley Plotkin
  • Hardcover ISBN: 9780323357616
  • eBook ISBN: 9780323393010

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From the development of each vaccine to its use in reducing disease, Plotkin’s Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin’s Vaccines is a must-have reference for current, authoritative information in this fast-moving field.

Key Features

  • Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies.
  • Analyzes the cost-benefit and cost-effectiveness of different vaccine options.
  • Helps you clearly visualize concepts and objective data through an abundance of tables and figures.

Table of Contents

  • Section 1: General Aspects of Vaccination

    1. A Short History of Vaccination

    2. Vaccine Immunology

    3. Correlates of Protection

    4. The Vaccine Industry

    5. Vaccine Manufacturing

    6. Evolution of Adjuvants Across the Centuries

    7. Vaccine Additives and Manufacturing Residuals in Vaccines Licensed in the United States

    8. Passive Immunization

    9. General Immunization Practices

    Section 2: Licensed Vaccines and Vaccines in Development

    10. Adenovirus Vaccines

    11. Anthrax Vaccines

    12. Biodefense and Special Pathogen Vaccines

    13. Cancer Vaccines

    14. Cholera Vaccines

    15. Combination Vaccines

    16. Cytomegalovirus Vaccines

    17. Dengue Vaccines

    18. Diarrhea Caused by Bacteria

    19. Diphtheria Toxoid

    20. Ebola Vaccines

    21. Enterovirus 71

    22. Epstein-Barr Virus Vaccines

    23. Haemophilus influenzae Type b Vaccines

    24. Hepatitis A Vaccines

    25. Hepatitis B Vaccines

    26. Hepatitis C Vaccines

    27. Hepatitis E Vaccines

    28. Herpes Simplex Virus Vaccines

    29. Human Immunodeficiency Virus Vaccines

    30. Human Papillomavirus Vaccines

    31. Inactivated Influenza Vaccines

    32. Influenza Vaccine—Live

    33. Japanese Encephalitis Vaccines

    34. Lyme Disease Vaccines

    35. Malaria Vaccines

    36. Maternal Immunization

    37. Measles Vaccines

    38. Meningococcal Capsular Group A, C, W, and Y Conjugate Vaccines

    39. Meningococcal Capsular Group B Vaccines

    40. Mumps Vaccines

    41. Noninfectious Disease Vaccines

    42. Norovirus Vaccines

    43. Parasitic Disease Vaccines

    44. Pertussis Vaccines

    45. Plague Vaccines

    46. Pneumococcal Conjugate Vaccine and Pneumococcal Common Protein Vaccines

    47. Pneumococcal Polysaccharide Vaccines

    48. Poliovirus Vaccine–Inactivated

    49. Poliovirus Vaccine–Live

    50. Rabies Vaccines

    51. Respiratory Syncytial Virus Vaccines

    52. Rotavirus Vaccines

    53. Rubella Vaccines

    54. Smallpox and Vaccinia

    55. Staphylococcus aureus Vaccines

    56. Streptococcus Group A Vaccines

    57. Streptococcus Group B Vaccines

    58. Tetanus Toxoid

    59. Tickborne Encephalitis Vaccines

    60. Tuberculosis Vaccines

    61. Typhoid Fever Vaccines

    62. Varicella Vaccines

    63. Yellow Fever Vaccines

    64. Zika Virus

    65. Zoster Vaccines

    Section 3: New Technologies

    66. Technologies for Making New Vaccines

    67. Development of Gene-Based Vectors for Immunization

    68. Technologies to Improve Immunization

    Section 4: Vaccination of Special Groups

    69. Vaccination of Immunocompromised Hosts

    70. Vaccination of Human Immunodeficiency Virus–Infected Persons

    71. Vaccines for International Travel

    72. Vaccines for Healthcare Personnel

    Section 5: Public Health and Regulatory Issues

    73. Immunization in the United States

    74. Immunization in Europe

    75. Immunization in the Asia-Pacific Region

    76. Immunization in Developing Countries

    77. Community Protection

    78. Economic Analyses of Vaccine Policies

    79. Regulation and Testing of Vaccines

    80. Regulation of Vaccines in Europe

    81. Regulation of Vaccines in Low- and Middle-Income Countries

    82. Vaccine Safety

    83. Legal Issues

    84. Ethics

    Appendix: Websites and Applications for Mobile Devices with Information about Immunization

Product details

  • No. of pages: 1720
  • Language: English
  • Copyright: © Elsevier 2017
  • Published: April 7, 2017
  • Imprint: Elsevier
  • Hardcover ISBN: 9780323357616
  • eBook ISBN: 9780323393010

About the Authors

Walter Orenstein

Affiliations and Expertise

Professor of Medicine and Pediatrics, and Global Health, Emory University; Associate Director, Emory Vaccine Center, Atlanta GA; Bill & Melinda Gates Foundation, Seattle, WA; Former Director, National Immunization Program, Centers for Disease Control and Prevention, Atlanta GA

Paul Offit

Affiliations and Expertise

Chief, Division of Infectious Diseases, Director, Vaccine Education Center, The Children's Hospital of Philadelphia; Professor of Pediatrics, Maurice R. Hilleman Professor of Vaccinology, Perelman School of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Kathryn M. Edwards

Affiliations and Expertise

Sarah H. Sell and Cornelius Vanderbilt Chair in Pediatrics, Professor of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee

Stanley Plotkin

Affiliations and Expertise

Emeritus Professor of Pediatrics, University of Pennsylvania, Emeritus Professor, Wistar Institute, Former Chief, Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA; Former Medical and Scientific Director, Pasteur Merieux Connaught (now Sanofi Pasteur), Marnes-la-Coquette, France

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