Plotkin's Vaccines - 7th Edition - ISBN: 9780323357616, 9780323393010

Plotkin's Vaccines

7th Edition

Authors: Stanley Plotkin Walter Orenstein Paul Offit Kathryn M. Edwards
Hardcover ISBN: 9780323357616
eBook ISBN: 9780323393010
Imprint: Elsevier
Published Date: 7th April 2017
Page Count: 1720

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From the development of each vaccine to its use in reducing disease, Plotkin’s Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin’s Vaccines is a must-have reference for current, authoritative information in this fast-moving field.

Key Features

  • Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies.
  • Analyzes the cost-benefit and cost-effectiveness of different vaccine options.
  • Helps you clearly visualize concepts and objective data through an abundance of tables and figures.

Table of Contents

Section 1: General Aspects of Vaccination

1. A Short History of Vaccination

2. Vaccine Immunology

3. Correlates of Protection

4. The Vaccine Industry

5. Vaccine Manufacturing

6. Evolution of Adjuvants Across the Centuries

7. Vaccine Additives and Manufacturing Residuals in Vaccines Licensed in the United States

8. Passive Immunization

9. General Immunization Practices

Section 2: Licensed Vaccines and Vaccines in Development

10. Adenovirus Vaccines

11. Anthrax Vaccines

12. Biodefense and Special Pathogen Vaccines

13. Cancer Vaccines

14. Cholera Vaccines

15. Combination Vaccines

16. Cytomegalovirus Vaccines

17. Dengue Vaccines

18. Diarrhea Caused by Bacteria

19. Diphtheria Toxoid

20. Ebola Vaccines

21. Enterovirus 71

22. Epstein-Barr Virus Vaccines

23. Haemophilus influenzae Type b Vaccines

24. Hepatitis A Vaccines

25. Hepatitis B Vaccines

26. Hepatitis C Vaccines

27. Hepatitis E Vaccines

28. Herpes Simplex Virus Vaccines

29. Human Immunodeficiency Virus Vaccines

30. Human Papillomavirus Vaccines

31. Inactivated Influenza Vaccines

32. Influenza Vaccine—Live

33. Japanese Encephalitis Vaccines

34. Lyme Disease Vaccines

35. Malaria Vaccines

36. Maternal Immunization

37. Measles Vaccines

38. Meningococcal Capsular Group A, C, W, and Y Conjugate Vaccines

39. Meningococcal Capsular Group B Vaccines

40. Mumps Vaccines

41. Noninfectious Disease Vaccines

42. Norovirus Vaccines

43. Parasitic Disease Vaccines

44. Pertussis Vaccines

45. Plague Vaccines

46. Pneumococcal Conjugate Vaccine and Pneumococcal Common Protein Vaccines

47. Pneumococcal Polysaccharide Vaccines

48. Poliovirus Vaccine–Inactivated

49. Poliovirus Vaccine–Live

50. Rabies Vaccines

51. Respiratory Syncytial Virus Vaccines

52. Rotavirus Vaccines

53. Rubella Vaccines

54. Smallpox and Vaccinia

55. Staphylococcus aureus Vaccines

56. Streptococcus Group A Vaccines

57. Streptococcus Group B Vaccines

58. Tetanus Toxoid

59. Tickborne Encephalitis Vaccines

60. Tuberculosis Vaccines

61. Typhoid Fever Vaccines

62. Varicella Vaccines

63. Yellow Fever Vaccines

64. Zika Virus

65. Zoster Vaccines

Section 3: New Technologies

66. Technologies for Making New Vaccines

67. Development of Gene-Based Vectors for Immunization

68. Technologies to Improve Immunization

Section 4: Vaccination of Special Groups

69. Vaccination of Immunocompromised Hosts

70. Vaccination of Human Immunodeficiency Virus–Infected Persons

71. Vaccines for International Travel

72. Vaccines for Healthcare Personnel

Section 5: Public Health and Regulatory Issues

73. Immunization in the United States

74. Immunization in Europe

75. Immunization in the Asia-Pacific Region

76. Immunization in Developing Countries

77. Community Protection

78. Economic Analyses of Vaccine Policies

79. Regulation and Testing of Vaccines

80. Regulation of Vaccines in Europe

81. Regulation of Vaccines in Low- and Middle-Income Countries

82. Vaccine Safety

83. Legal Issues

84. Ethics

Appendix: Websites and Applications for Mobile Devices with Information about Immunization


No. of pages:
© Elsevier 2017
7th April 2017
Hardcover ISBN:
eBook ISBN:

About the Authors

Stanley Plotkin

Affiliations and Expertise

Emeritus Professor of Pediatrics, University of Pennsylvania, Emeritus Professor, Wistar Institute, Former Chief, Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA; Former Medical and Scientific Director, Pasteur Merieux Connaught (now Sanofi Pasteur), Marnes-la-Coquette, France

Walter Orenstein

Affiliations and Expertise

Professor of Medicine and Pediatrics, and Global Health, Emory University; Associate Director, Emory Vaccine Center, Atlanta GA; Bill & Melinda Gates Foundation, Seattle, WA; Former Director, National Immunization Program, Centers for Disease Control and Prevention, Atlanta GA

Paul Offit

Affiliations and Expertise

Chief, Division of Infectious Diseases, Director, Vaccine Education Center, The Childrne's Hospital of Philadelphia; Professor of Pediatrics, Maurice R. Hilleman Professor of Vaccinology, Perelman School of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, PA.

Kathryn M. Edwards

Affiliations and Expertise

Sarah H. Sell and Cornelius Vanderbilt Chair in Pediatrics Professor of Pediatrics, Vanderbilt University School of Medicine.