Platform Technologies in Drug Discovery and Validation - 1st Edition - ISBN: 9780128130698

Platform Technologies in Drug Discovery and Validation, Volume 50

1st Edition

Serial Volume Editors: Robert Goodnow
Hardcover ISBN: 9780128130698
Imprint: Academic Press
Published Date: 1st December 2017
Page Count: 310
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Table of Contents

1. DELT

  Barry Morgan

2. Oligos: ASO, siRNA

  Dave Rozema

3. CRISPR

  Sylvie Guichard

4. Mircro-fluidic chemistry

  Ürge László

5. High throughput screening

  Jonathan Connick

6. Kinase-centric computational drug development

  Andrea Volkamer and Albert J. Kooistra

7. Virtual Screening

  Mark Ashwell

8. Phenotypic screening

  Alleyn Plowright

9. PROTACS

  Tim Rassmussen

10. Chemical Biology

  Paola Castaldi and Piero Ricchiuto

11. Fragment-based lead generation

  Ben Davis

12. Antibody-Drug Conjugates

  Changshou Gao

13. Antibody-recruiting small molecules

  Andrew Zhang, Patrick McEnaney and Christopher Parker

14. Deuteriation

  Dario Doller

15. Peptides

  Claudio D. Schteingart


Description

Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies.

Key Features

  • Unique for its treatment of platform technologies for medicinal chemistry and target validation
  • Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field
  • Presents state-of-the-art summaries of platform technologies

Readership

Ideally suited for chemists engaged in multidisciplinary teams for drug discovery including medicinal chemists and others involved in chemical biology and bio-organic disciplines and computational chemistry


Details

No. of pages:
310
Language:
English
Copyright:
© Academic Press 2017
Published:
Imprint:
Academic Press
Hardcover ISBN:
9780128130698

About the Serial Volume Editors

Robert Goodnow Serial Volume Editor

Robert A. Goodnow, Jr. is currently Vice President, Chemistry Innovation at Pharmaron, Inc in Boston, MA. He completed a Ph.D. in bioorganic chemistry at Columbia University, New York, USA, followed by postdoctoral training at Princeton University, New Jersey, USA. He has worked at Roche and AstraZeneca, focusing on new lead and target discovery as well as implementing chemistry technologies in support of early drug discovery. He is the editor and author of The Handbook of DNA-Encoded Chemistry, which was published in 2014 by Wiley.

Affiliations and Expertise

Pharmaron, Boston, USA