COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Platelets: Receptors, Adhesion, Secretion, Part A - 1st Edition - ISBN: 9780121820701, 9780080882864

Platelets: Receptors, Adhesion, Secretion, Part A, Volume 169

1st Edition

Editors in Chief: John Abelson Melvin Simon
Serial Volume Editor: Jacek Hawiger
Hardcover ISBN: 9780121820701
eBook ISBN: 9780080882864
Imprint: Academic Press
Published Date: 28th February 1989
Page Count: 512
Sales tax will be calculated at check-out Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

Isolation of Platelets: J.F. Mustard, R.L. Kinlough-Rathbone, and M.A. Packham, Isolation of Human Platelets from Plasma by Centrifugation and Washing. S. Timmons and J. Hawiger, Isolation of Human Platelets by Albumin Gradient and Gel Filtration. B. Rucinski and S. Niewiarowski, Isolation and Characterization of Porcine Platelets. J.L. Catalfamo and W.J. Dodds, Isolation of Platelets from Laboratory Animals. Platelet Adhesion, Aggregation, and Turnover: K.S. Sakariassen, R. Muggli, and H.R. Baumgartner, Measurements of Platelet Interaction with Components of the Vessel Wall in Flowing Blood. G.L. Fry and J.C. Hoak, Measurement of Platelet Interaction with Endotheliel Monolayers. A. Eldor, Z. Fuks, R.F. Levine, and I. Vlodavsky, Measurement of Platelet and Megakaryocyte Interaction with the Subendothelial Extracellular Matrix. K. Park, D.F. Mosher, and S.L. Cooper, Ex Vivo Measurement of Platelet Adhesion to Polymeric Surfaces. J.N. Lindon, L. Kushner, and E.W. Salzman, Platelet Interaction with Artificial Surfaces: In Vitro Evaluation. M.B. Zucker, Platelet Aggregation Measured by the Photometric Method. M.M. Frojmovic, J.G. Milton, and A.L. Gear, Platelet Aggregation Measured in Vitro by Microscopic and Electronic Particle Counting. K.M. Brinkhous and M.S. Read, Use of Fixed Platelets in Agglutination/Aggregation Tests. D. Bessman, Determination of Platelet Volume and Number. W.A. Heaton, A. du P. Heyns, and J.H. Joist, Measurement of in Vivo Platelet Turnover and Organ Distribution Using 111In-Labeled Platelets. Platelet Secretion: J. Hawiger, Platelet Secretory Pathways: An Overview. Dense Granule Constituents: H. Holmsen and C. Dangelmaier, Measurement of Secretion of Adenine Nucleotides. H. Holmsen and C. Dangelmaier, Measurement of Secretion of Serotonin. Alpha Granule Constituents: H.N. Antoniades and P. Pantazis, Platelet-Derived Growth Factor: Purification and Characterization. J.C. Holt and S. Niewiarowski, Platelet Basic Protein, Low-Affinity Platelet Factor 4, and ~gb-Thromboglobulin: Purification and Identification. R.M. Senior, G.L. Griffin, A. Kimura, J.S. Huang, and T.F. Deuel, Platelet ~ga-Granule Protein-Induced Chemotaxis of Inflammatory Cells and Fibroblasts. M.F. Lopez-Fernandez, J. Batlle, Z.M. Ruggeri, and T.S. Zimmerman, Secretion of von Willebrand Factor from Platelets. H.S. Slayter, Secretion of Thrombospondin from Human Blood Platelets. L.L.K. Leung, P.C. Harpel, and R.L. Nachman, Platelet Histidine-Rich Glycoprotein. A.H. Schmaier and R.W. Colman, Platelet High Molecular Weight Kininogen. E.F. Plow, L.A. Miles, and D. Collen, Platelet ~ga-2 Antiplasmin. J.J. Sixma, J-W. Slot, and H.J. Geuze, Immunocytochemical Localization of Platelet Granule Proteins. C.L. Berman, E.L. Yeo, B.C. Furie, and B. Furie, PADGEM Protein. H.S. Slayter, Dark-Field Electron Microscopy of Platelet Adhesive Macromolecules. Lysosomal Enzymes: H. Holmsen and C. Dangelmaier, Measurement of Secretion of Lysosomal Acid Glycosidases. R.D. Rosenberg, Platelet Heparitinase. Regulation of Platelet Function: L.F. Brass and S.J. Shattil, Interaction of Extracellular Calcium with Surface Membrane of Human Platelets. L.F. Brass and E. Belmonte, Calcium-45 Exchange Techniques to Study Calcium Transport in Intact Platelets. P.C. Johnson, J.A. Ware, and E.W. Salzman, Measurement of Platelet Cytoplasmic Ionized Calcium Concentration with Aequorin and Fluorescent Indicators.


The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.


Biochemists, cell biologists, hematologists, pharmacologists, physiologists, and neurochemists.


No. of pages:
© Academic Press 1989
28th February 1989
Academic Press
Hardcover ISBN:
eBook ISBN:


@from:Praise for the Volume @qu:"I would highly recommend this extremely informative book...The price is reasonable for a volume of this size which has now become a welcome addition to my bookshelf." @source:--TRENDS IN PHARMACOLOGICAL SCIENCES @from:Praise for the Series @qu:"The Methods in Enzymology series represents the gold-standard." @source:--NEUROSCIENCE @qu:"Incomparably useful." @source:--ANALYTICAL BIOCHEMISTRY @qu:"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." @source:--BIO/TECHNOLOGY @qu:"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection." @source:--CHEMISTRY IN INDUSTRY @qu:"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced." @source:--AMERICAN SOCIETY OF MICROBIOLOGY NEWS @qu:"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work." @source:--ENZYMOLOGIA @qu:"A series that has established itself as a definitive reference for biochemists." @source:--JOURNAL OF CHROMATOGRAPHY

Ratings and Reviews

About the Editors in Chief

John Abelson

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

About the Serial Volume Editor

Jacek Hawiger

Affiliations and Expertise

University of Birmingham