Planar Cell Polarity During Development, Volume 101

1st Edition

Serial Volume Editors: Yingzi Yang
Hardcover ISBN: 9780123945921
eBook ISBN: 9780123948007
Imprint: Academic Press
Published Date: 21st November 2012
Page Count: 360
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Table of Contents

Series Page



Chapter One. The frizzled/stan Pathway and Planar Cell Polarity in the Drosophila Wing

1 Introduction to Drosophila Planar Cell Polarity

2 The Cellular Basis for PCP

3 PCP Genes

4 What is the Basis for the Asymmetric Localization of fz/stan Pathway Proteins?

5 Directional Cell Nonautonomy

6 Downstream Effectors


Note added in Proof

Chapter Two. Asymmetric Protein Localization in Planar Cell Polarity

1 Introduction

2 Revisiting the Three-Tiered Hierarchy of PCP

3 Asymmetric Protein Localization: A Hallmark of PCP

4 The Ways and Means to Planar Polarize a Cell: Mechanisms of Achieving Asymmetry


Chapter Three. Control of Cell Polarity and Asymmetric Division in C. elegans

1 Cortical Asymmetry of Wnt Signaling Components

2 Connecting Cell Cortex to Nuclei

3 Asymmetric Regulation of Transcription in Nuclei

4 Spindle Orientation and MTOC Positioning

5 Wnts Instructively Orient Polarity of the EMS and T Cells

6 Coordination of Spindle Orientation by MOM-2/Wnt

7 Coordination of Asymmetric Cell Divisions During Embryogenesis

8 Coordination of Asymmetric Cell Divisions During Postembryonic Development

9 Polarity Reversal in Normal Development

10 Functions of PCP Components in C. elegans

11 Summary and Perspective


Chapter Four. Planar Cell Polarity in Coordinated and Directed Movements

1 Introduction

2 Coordinated and Directed Movements During Vertebrate Gastrulation

3 Planar Cell Polarity Signaling in Vertebrates

4 PCP Regulating CE and Collective Cell Migration in Other Contexts

5 PCP in Mediating Collectiveness and Polarized Behaviors

6 Concluding Remarks


Chapter Five. Planar Cell Polarity


This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in axon pathfinding.

Key Features

  • Covers the area of planar cell polarity
  • International board of authors
  • 12 chapters provide a comprehensive set of reviews covering such topics as planar cell polarity in Zebrafish, the role of disheveled in planar cell polarity regulation, and planar cell polarity in axon path finding


Researchers in cell, developmental, and molecular biology; genetics


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© Academic Press 2012
Academic Press
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About the Serial Volume Editors

Yingzi Yang Serial Volume Editor