Physiology and Biochemistry

Physiology and Biochemistry

2nd Edition - January 1, 1973

Write a review

  • Editor: Geoffrey Bourne
  • eBook ISBN: 9780323161558

Purchase options

Purchase options
DRM-free (PDF, Mobi, EPub)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


The Structure and Function of Muscle, Second Edition, Volume III: Physiology and Biochemistry presents the physiology and biochemistry of muscle. This book discusses the various aspects of the structure of muscles and explores some aspects of muscle disease. Organized into 10 chapters, this edition begins with an overview of the transverse tubular system or T system of striated muscle. This text then examines the properties and function of membranes through electron microscopy. Other chapters consider in more detail from a biophysical viewpoint certain aspects of the series of events surrounding muscle contraction. This book discusses as well the significance of the central circulation and the amount of oxygen that can be delivered by the cardiovascular system. The final chapter deals with the heat output and chemical breakdown during an isometric twitch. This book is a valuable resource for scientists, neurobiologists, biologists, biochemists, physiologists, histologists, cytologists, and research workers.

Table of Contents

  • List of Contributors


    Preface to the First Edition

    Contents of Other Volumes

    1. Electrical Properties of the Transverse Tubular System

    I. Introduction

    II. Mathematical Analysis

    III. Tubular Capacity—Lumped or Distributed?

    IV. Excitation—Contraction Coupling


    2. The Neuromuscular Junction—The Role of Acetylcholine in Excitable Membranes

    I. Excitable Membranes

    II. Role of Acetylcholine in Nerve Activity

    III. Enzymes Hydrolyzing and Forming Acetylcholine

    IV. AcCh Receptor Protein

    V. Similarities and Differences between Axonal and Junctional Membranes

    VI. Bioenergetics of Nerve Impulse Conduction

    VII. Concluding Remarks—Concepts and Axioms in Science


    3. Some Aspects of the Biophysics of Muscle

    I. Introduction

    II. Excitation

    III. Sodium and Potassium Fluxes and Distribution in Muscle

    IV. Mechanics

    V. Heat

    VI. Unanswered Questions


    4. Energy Need, Delivery, and Utilization in Muscular Exercise

    I. Introduction

    II. Extramuscular Lipid Stores

    III. Extramuscular Carbohydrate Stores

    IV. Amino Acids as a Source of Energy

    V. Uptake of Substrate from Blood

    VI. Use of Energy Stores in Skeletal Muscles

    VII. Substrate Consumption at Different Work Intensities and Duration


    5. The Control of Muscular Activity by the Central Nervous System

    I. Introduction

    II. Normal Use of Skeletal Muscle by the Primate

    III. Segmental Organization

    IV. Longitudinal Organization

    V. The Motor Cortices

    VI. Posture

    VII. Progression

    VIII. Tone in Skeletal Muscle

    IX. Phasic Movements

    X. Coordinated Movements as Response to Sensory Stimuli

    XI. Spontaneous or Self-Initiated Movements

    XII. Conclusions


    6. Electromyography

    I. Introduction

    II. Motor Units and Motor Unit Potentials

    III. Technology

    IV. EMG Kinesiology

    V. Neuromuscular Physiology


    7. Proteins of the Myofibril

    I. Introduction

    II. Myosin

    III. Actin

    IV. Regulatory Proteins

    V. Some Aspects of Myofibrillar Proteins


    8. Biochemistry of Muscle

    I. Energy Provision in Muscle

    II. Interaction of Adenosine Triphosphate and Actomyosin as the Basis of Muscle Contraction

    III. The Regulation of Carbohydrate Metabolism for Energy Supply

    IV. Relaxation

    V. Biochemical Effects on the Muscle Equipment of Repeated Stimulation, Denervation, and Cross Innervation

    VI. Conclusion


    9. Biochemistry of Muscle Mitochondria

    I. Introduction

    II. Function of Muscle Mitochondria

    III. Detailed Mechanisms of Energy-Yielding Reactions in Muscle Mitochondria

    IV. Energy-Consuming Reactions in Muscle Mitochondria

    V. Structure of Muscle Mitochondria and Localization of Enzymes within the Mitochondria

    VI. Interrelationships between Mitochondrial and Extramitochondrial Processes in Muscle


    10. ATP Breakdown Following Activation of Muscle

    I. Historical Introduction

    II. Action Potential

    III. Activation

    IV. Isometric Contraction

    V. Shortening

    VI. Positive Work

    VII. Negative Work

    VIII. Relaxation

    IX. Total Energy (Heat + Work) and Chemical Change


    Author Index

    Subject Index

Product details

  • No. of pages: 574
  • Language: English
  • Copyright: © Academic Press 1973
  • Published: January 1, 1973
  • Imprint: Academic Press
  • eBook ISBN: 9780323161558

About the Editor

Geoffrey Bourne

Ratings and Reviews

Write a review

There are currently no reviews for "Physiology and Biochemistry"