Pharmacology and Therapeutics - 1st Edition - ISBN: 9781416032915

Pharmacology and Therapeutics

1st Edition

Principles to Practice

Authors: Scott Waldman Andre Terzic
Hardcover ISBN: 9781416032915
Imprint: Saunders
Published Date: 8th December 2008
Page Count: 1536


Pharmacology and Therapeutics: Principles to Practice uses pharmacology principles to integrate the most recent advances in basic biomedical sciences into deciding the best medications to treat illness and preserve health.

Edited by Scott A. Waldman, MD, PhD, FCP and Andre Terzic, MD, PhD, this brand-new multimedia resource fills a critical need for a more clinically focused, user-friendly pharmacology reference. Get everything you need to know about all of today's drugs in a coherent, easy-to-use format - from the underlying science through innovation, translation, regulation, and clinical implementation. Evidence-based therapeutic guidelines facilitate decision making; and coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine keeps you at the forefront of the latest developments. Reference is a snap due to the book's logical, user-friendly format.

Key Features

  • Features a logical organization (by body system, rather than by drug class) and an exceptionally user-friendly format so you can find the clinically actionable information you need more easily.
  • Offers evidence-based therapeutic guidelines to help you make sound clinical decisions.
  • Includes cutting-edge coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine across medical specialties.
  • Examines nutrition, complementary and alternative medicines, neutraceuticals, and dietary supplements, allowing you to effectively counsel patients and avoid dangerous drug interactions.

Table of Contents


Section 1: Pharmacotherapeutic Continuum

1 Drug Discovery
2 Drug Development
3 Regulations and Pharmacovigilence
4 Evidence-Based Drug Utilization

Section 2: Molecular Pharmacology

5 Drug-Receptor Interactions
6 Signal Transduction
7 "Cell Cycle Pharmacology, Antiproliferation, and Apoptosis"

Section 3: Systems Pharmacology

8 Neurotransmitters
9 Autonomic Pharmacology
10 Fluid and Electrolyte Homeostasis
11 Inflammation and Immunomodulation
12 Pharmacobiology of Infections

Section 4: Clinical Pharmacology

13 Pharmacokinetics
14 Pharmacodynamics
15 Pharmacogenetics and Pharmacogenomics
16 Heterogenity of Drug Responses and Individualization of Therapy
17 Pediatric Pharmacology
18 Gender Influences on Pharmacology
19 Pharmacology Across the Aging Continuum
20 Adverse Drug Reactions and Interactions
21 Therapeutic Monitoring

PART II: Practice

Section 5: Cardiovascular Therapeutics

22 Hypertension
23 Dyslipidemias
24 Coronary Artery Disease
25 Rhythm Disorders
26 Heart Failure

Section 6: Pulmonary Therapeutics

27 Pulmonary Arterial Hypertension
28 Asthma and Chronic Obstructive Pulmonary Disease

Section 7: Renal Therapeutics

29 Renal Insufficiency
30 Voiding Dysfunction

Section 8: Gastroenterologic Therapeutics

31 Acid Reflux and Ulcer Disease
32 Motility Disorders
33 Inflammatory Bowel Diseases
34 Hepatic Cirrhosis
35 Infectious Hepatitis

Section 9: Endocrinologic Therapeutics

36 Obesity and Nutrition
37 Diabetes Mellitus
38 Disorders of the Thyroid
39 Disorders of Calcium Metabolism and Bone Mineralization
40 Disorders of the Hypothalamic Pituitary Axis
41 Adrenal Disorders
42 Reproductive Health

Section 10: Neuropharmacologic Therapeutics

43 Alzheimer's Disease a


No. of pages:
© Saunders 2009
Hardcover ISBN:

About the Author

Scott Waldman

Affiliations and Expertise

Samuel M.V. Hamilton Professor of Medicine and Professor of Biochemistry and Molecular Pharmacology; Director of Clinical Pharmacology, Thomas Jefferson University Philadelphia, PA

Andre Terzic

Affiliations and Expertise

Professor of Medicine, Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School; Vice-Chair Cardiovascular Research, Mayo Clinic, Mayo Foundation, Rochester, NY