Pharmaceutics

1st Edition

Basic Principles and Application to Pharmacy Practice

Authors:

  • Alekha Dash
  • Somnath Singh
  • Justin Tolman
  • Pharmaceutics

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    Description

    Pharmaceutics: Basic Principles and Application to Pharmacy Practice is a valuable textbook covering the basic science as well as the role and application of pharmaceutics within pharmacy practice. Based on curricular guidelines mandated by the American Council for Pharmacy Education (ACPE), this book incorporates laboratory skills by identifying portions of each principle that can be used in a clinical setting. In this way, instructors are able to demonstrate their adherence to ACPE standards and objectives simply by using this book. A companion website for students and instructors further enhance the didactic content for students by including practice questions and answers and videos that feature difficult processes and procedures. Essential resources for instructors are also available and include chapter PowerPoint slides and full-color images. Full of practical examples and case studies for experiential learning, Pharmaceutics enables students to gain the scientific foundation to understand drug physicochemical properties, practical aspects of dosage forms and drug delivery systems, and the biological applications of drug administration. 

    Key Features

    • Chapter objectives and chapter summaries illustrate and reinforce key ideas
    • Designed to meet curricular guidelines for pharmaceutics and laboratory skills mandated by the Accreditation Council for Pharmacy Education (ACPE)
    • Companion website features resources for students and instructors, including videos illustrating difficult processes and procedures and practice questions and answers.  Instructor resources include Powerpoint slides and a full-color image bank

    Readership

    For students in pharmaceutical science programs taking pharmaceutics or biopharmaceutics courses at the undergraduate, graduate and doctoral level.

    Table of Contents

    Dedication

    Preface

    Acknowledgments

    List of Contributors

    Part I: Physical Principles and Properties of Pharmaceutics

    Chapter 1. Introduction: Terminology, Basic Mathematical Skills, and Calculations

    1.1 Introduction

    1.2 Review of Basic Mathematical Skills

    1.3 Graphical Representation

    1.4 Dimensions and Units

    1.5 Conclusions

    Case Studies

    References

    Chapter 2. Physical States and Thermodynamic Principles in Pharmaceutics

    2.1 Introduction

    2.2 Composition of Matter

    2.3 Forces of Attraction and Repulsion

    2.4 States of Matter

    2.5 Thermodynamics

    2.6 Basic Concepts and Definitions

    2.7 The First Law of Thermodynamics

    2.8 Enthalpy and Heat Capacity

    2.9 The Second Law of Thermodynamics

    2.10 The Third Law of Thermodynamics

    2.11 Free Energy and Thermodynamic Functions

    2.12 Chemical Equilibrium

    2.13 Open Systems

    2.14 Conclusions

    Case Studies

    Appendix 2.1 Calculus Review

    References

    Chapter 3. Physical Properties, Their Determination, and Importance in Pharmaceutics

    3.1 Introduction

    3.2 Surface and Interfacial Tension

    3.3 Adsorption

    3.4 Solubilization

    3.5 Rheology

    3.6 Colligative Properties

    3.7 Osmolarity and Osmolality

    3.8 Solubility and Solutions of Nonelectrolytes

    3.9 Spectroscopy

    3.10 Conclusions

    Case Studies

    References

    Chapter 4. Equilibrium Processes in Pharmaceutics

    4.1 Introduction

    4.2 Gastrointestinal Physiology

    4.3 Ionization

    4.4 Partition Coefficient: Lipophilicity

    4.5 Equilibrium Solubility

    4.6 The Effect of pH

    4.7 Use of Co-solvents

    4.8 Drug Dissolution and Dissolution Process

    4.9 Factors Influencing the Dissolution Rate

    4.10 Passive Diffusi

    Details

    No. of pages:
    392
    Language:
    English
    Copyright:
    © 2014
    Published:
    Imprint:
    Academic Press
    Print ISBN:
    9780123868909
    Electronic ISBN:
    9780123868916

    Reviews

    "Pharmaceutics is an important part of the practice of pharmacy. This book outlines pharmaceutics and uses chapter summary questions and case studies to reinforce the concepts…This book is appropriate for pharmaceutical science, pharmacy, and biomedical sciences courses. It is written at a level that is easy to follow and provides practical examples. Compared to other pharmaceutics books…this one is up to date and student-friendly." Rating: 4 Stars--Doody.com, March 21, 2014