Perspectives in Basic and Applied Toxicology - 1st Edition - ISBN: 9780723608370, 9781483193533

Perspectives in Basic and Applied Toxicology

1st Edition

Editors: Bryan Ballantyne
eBook ISBN: 9781483193533
Imprint: Butterworth-Heinemann
Published Date: 18th January 1988
Page Count: 406
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Perspectives in Basic and Applied Toxicology features a collection of essays on various aspects of toxicology. It aims to relate fundamental knowledge of toxicology to its application in assessing relevance of that information to the causation of adverse health effects, predicting hazardous situations, defining protective and precautionary measures, and the recognition and management of intoxication in humans. Another objective of this volume is to encourage those with responsibility for the training of toxicologists to instill a greater concern about ethical and moral issues as fundamental to the practice of toxicology as a profession with wide-ranging social implications. This book is organized into 14 chapters. The coverage of these chapters include assessment of chemical hazards in the workplace, the relation between animal studies and epidemiology in the context of industrial toxicology, carcinogenicity testing in animals, and biochemical evaluation of neurotoxicity.
This book will be of interest to undergraduate and graduate toxicologists, pharmacologists, physicians, industrial hygienists, and other health professionals.

Table of Contents

1. Biochemical Methods for Assessment of Neurotoxicity

2. Chemical Excitants of Cutaneous Pain

3. Ototoxicity: Morphological and Functional Correlations between Experimental and Clinical Studies

4. Xenobiotic-Induced Rhabdomyolysis

5. Drug-Induced Oesophagitis

6. Review of Recent Advances in the Development and Application of the Micronucleus Test System

7. Chemical Induction of Dominant Lethal Mutations in Mammals

8. Developmental Toxicity in Toxicologic Research and Testing

9. The Role of Genetic Differences as a Determinant in Xenobiotic-Induced Developmental Toxicity

10. A Survey of In Vitro Teratology Tests

11. Carcinogenicity Tests in Animals: Some Pitfalls That Could Be Avoided

12. Experimental Approaches to the Design and Assessment of Antidotal Procedures

13. The Interaction between Epidemiology and Animal Studies in Industrial Toxicology

14. Practical Assessment and Communication of Chemical Hazards in the Workplace



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About the Editor

Bryan Ballantyne

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