Perinatal Genetics: Diagnosis and Treatment brings together the proceedings of the 15 Annual New York State Health Department Birth Defects Symposium held on September 30-October 1, 1984 in Albany, New York. The symposium provided a forum for clarifying and rationalizing certain aspects of diagnosis and treatment of perinatal genetic birth defects such as fragile X syndrome, phenylketonuria, and hypothyroidism.
Comprised of 17 chapters, this book begins with an epidemiological review of very early pregnancy loss, focusing on fertilization and implantation; the probability of loss between fertilization and implantation (on about the sixth day), and between implantation and the 14th day (the first day of the expected next period in a non-pregnant woman); and the contribution of chromosomal errors in the sperm, ovum, and zygote to early reproductive loss. The reader is then introduced to cytogenetic abnormalities in spontaneous abortions of recognized conceptions; repetitive spontaneous abortion; and prenatal genetic diagnosis by chorionic villus sampling. Subsequent chapters explore prenatal treatment of biochemical disorders; in vitro fertilization and embryo transfer; and moral issues concerning third trimester pregnancy terminations.
This monograph will appeal to perinatologists, neonatologists, obstetricians, pediatricians, and geneticists and should also serve as a useful guide for health professionals who provide care to pregnant women and their newborns.
Very Early Pregnancy: Fertilization and Implantation Frequency and Cause of Loss
Cytogenetic Abnormalities in Spontaneous Abortions of Recognized Conceptions
Repetitive Spontaneous Abortion
Prenatal Diagnosis of the Fragile X Syndrome
Prenatal Diagnosis and Carrier Detection of Classical Phenylketonuria
Prenatal Genetic Diagnosis by Chorionic Villus Sampling
Prenatal Treatment of Biochemical Disorders
Fetal Surgery, Old Controversies about New Therapies
Diagnosis and Management of Ambiguous Genitalia in the Newborn
Current Perspectives on Fetal Hydrocephalus
In Vitro Fertilization and Embryo Transfer
H-Y Antigen, Sex Determination and Gender Control
Environmental Factors and Human Birth Defects: Interpretation of Relative Risks in Clinical Genetics
Results of New York State Newborn Hypothyroidism Screening Program
Paternal Age and Genetic Outcome: Implications for Genetic Counseling
Pedigrees or Catalogs?
When Are Third Trimester Pregnancy Terminations Morally Justifiable?
- No. of pages:
- © Academic Press 1986
- 28th January 1986
- Academic Press
- eBook ISBN: