Perinatal and Neonatal Infections, An Issue of Clinics in Perinatology

1st Edition, Volume 48-2 - June 3, 2021
Editors: Joseph B. Cantey, Andi Shane
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 7 0 5 - 8
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 7 0 6 - 5

In this issue of Clinics in Perinatology, guest editors Joseph B. Cantey and Andi Shane bring their considerable expertise to the topic of Perinatal and Neonatal Infections.… Read more

Perinatal and Neonatal Infections, An Issue of Clinics in Perinatology

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In this issue of Clinics in Perinatology, guest editors Joseph B. Cantey and Andi Shane bring their considerable expertise to the topic of Perinatal and Neonatal Infections.

Cover image
Title page
Table of Contents
Copyright
Contributors
CME Accreditation Page
Forthcoming Issues
Foreword
Preface
Biomarkers for the Diagnosis of Neonatal Sepsis
Key points
Introduction
Definitions
Challenges in sepsis diagnostics
Current biomarkers
Complete blood count
C-reactive protein
Procalcitonin
Others
Optimal current practice
Future research
Clinics care points
Necrotizing Enterocolitis
Key points
Introduction
Epidemiology
Pathophysiology
Advances in preventive/therapeutic options
Summary
Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome
Key points
Introduction
Epidemiology of neonatal bacterial infections
Pathogenesis of infection and brain injury
Perinatal inflammation and neurodevelopmental outcomes
Neurodevelopmental outcomes after neonatal infections
Summary
Clinics care points
Neonatal Herpes Simplex Virus Disease: Updates and Continued Challenges
Key points
Introduction
Classifications of neonatal herpes simplex virus disease
Transmission
Discussion
Summary
Clinics care points
Disclosure
HIV in Neonates and Infants
Key points
History, epidemiology, and elimination of mother-to-child transmission
Prevention of mother-to-child transmission of HIV
Neonatal HIV treatment
Alternatives to first line antiretroviral regimen and therapies under investigation
Complications in HIV-exposed and -infected children
The future and need
Syphilis in Neonates and Infants
Introduction
Epidemiology
Transmission
Clinical manifestations
Diagnosis, evaluation, and treatment
Prognosis and follow-up
Prevention
Ebola, Dengue, Chikungunya, and Zika Infections in Neonates and Infants
Key points
Background
Ebola virus disease
Zika virus
Chikungunya
Dengue
Summary
Clinics care points
Disclosure
Chagas Disease: Implementation of Screening to Benefit Mother and Infant
Key points
Introduction
Discussion
Clinics care points
Summary
Hepatitis C Virus in Neonates and Infants
Key points
Introduction
Epidemiology
Guidelines: Hepatitis C virus testing in pregnant women
Current evidence: Hepatitis C virus in pregnancy
Vertical transmission: Pathogenesis
Vertical transmission: Risk factors
Guidelines: infant hepatitis C virus testing
Natural history and monitoring of hepatitis C virus infection in infants
Treatment
Discussion: Future research
Summary
Clinics care points
Disclosure
The Role of Breast Milk in Infectious Disease
Key points
Background
Breast milk anti-infective properties
Transmitted infections and human milk
Common viral infections
Bacterial infections
Other infections
Emerging Infections: Human milk and severe acute respiratory syndrome novel coronavirus 2
Maternal vaccination during lactation
Special considerations: Donor milk
Breast milk handling considerations
Summary
Clinics care points
Disclosure
Antibiotic Stewardship for the Neonatologist and Perinatologist
Key points
Introduction
Stewardship targets
Implementation
Summary
Clinics care points
Immunization in the Neonatal Intensive Care Unit
Key points
Introduction
Maternal vaccination for newborn protection
Neonatal/infant vaccination
Special considerations for immunizations in the neonatal intensive care unit
Summary
Disclosure
Infection Prevention in the Neonatal Intensive Care Unit
Key points
Introduction
Healthcare-associated infections in the neonate
Infection prevention and control infrastructure and health care–associated infection surveillance in the neonatal intensive care unit
General infection prevention and control concepts and considerations in the neonate
Mitigating risk of potential exposures in the neonatal intensive care unit
Infection prevention and control bundles and multimodal improvement strategies
Limited-resource settings
Summary
Clinics care points
Disclosures