Pericyclic Chemistry

Pericyclic Chemistry: Orbital Mechanisms and Stereochemistry is a complete guide to the topic that is ideal for graduate students, advanced undergraduate students and researchers in organic chemistry. An introduction to molecular orbital theory and relevant stereochemical concepts is provided as background, with all four classes of pericyclic reactions discussed and illustrated with orbital picture representations. Also included are chapters on cycloadditions, the most versatile class, and electrocyclic reactions, sigmatropic rearrangements and group transfer reactions. A separate chapter on the construction of correlation diagrams is also included, emphasizing a practical, hands on approach.

Author Dipak Kumar Mandal brings over 30 years of teaching experience to the topic and illuminates pericyclic chemistry with a clear and fresh perspective.

• Comprehensive guide featuring unifying mechanistic approaches, stereochemical details and novel rules and mnemonics to delineate product stereochemistry
• Includes two background chapters on molecular orbitals and stereochemical concepts
• Emphasizes a theoretical understanding using perturbation theory (Salem-Klopman equation) and physical insights from orbital and state correlation analyses

Graduate and advanced undergraduate students of organic chemistry, researchers in organic chemistry

1. Molecular Orbitals
2. Stereochemical concepts
3. Pericyclic reactions: Introduction, classification and the Woodward-Hoffmann rules
4. Cycloadditions 1: Perturbation theory of reactivity, regioselectivity and periselectivity
5. Cycloadditions 2: Stereochemistry of [4+2] and [2+2] cycloadditions
6. Cycloadditions 3: Cheletropic, higher order and multicomponent cycloadditions
7. Electrocyclic reactions: Stereochemistry and torquoselectivity
8. Sigmatropic rearrangements 1: [1,j] Shifts
9. Sigmatropic rearrangements 2: [i,j] Shifts
10. Group transfer reactions
11. Correlation diagrams