Peptides

1st Edition

Synthesis, Structures, and Applications

Editors: Bernd Gutte
Hardcover ISBN: 9780123109200
eBook ISBN: 9780080538594
Imprint: Academic Press
Published Date: 19th October 1995
Page Count: 511
72.95 + applicable tax
43.99 + applicable tax
54.95 + applicable tax
155.00 + applicable tax
Unavailable
Compatible Not compatible
VitalSource PC, Mac, iPhone & iPad Amazon Kindle eReader
ePub & PDF Apple & PC desktop. Mobile devices (Apple & Android) Amazon Kindle eReader
Mobi Amazon Kindle eReader Anything else

Institutional Access


Description

In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides.

Key Features

@introbul:Coverage includes: @bul:* The history of peptide chemistry

  • Amide formation, deprotection, and disulfide formation in peptide synthesis
  • Solid-phase peptide synthesis
  • a-helix formation by peptides in water
  • Stability and dynamics of peptide conformation
  • An overview of structure-function studies of peptide hormones
  • Neuropeptides:peptide and nonpeptide analogs
  • Reversible inhibitors of serine proteinases
  • Design of polypeptides
  • Current capabilities and future possibilities of soluble chemical combinatorial libraries
  • Epitope mapping with peptides
  • Synthesis and applications of branched peptides in immunological methods and vaccines

Table of Contents

(Chapter Headings) the History of Peptide Chemistry. Amide Formation, Deprotection, And Disulfide Formation in Peptide Synthesis. Solid Phase Peptide Synthesis. A-Helix Formation By Peptides in Water. Peptide Conformation: Stability and Dynamics. Structure-Function Studies of Peptide Hormones: An Overview. Neuropeptides: Peptides and Nonpeptide Analogs. Reversible Inhibitors of Serine Proteinases, Naturallly Occurring Miniproteins, Semisynthetic Variants, Recombinant Homologues and Synthetic Peptides. Design of Polypeptides. Chemical Combinatorial Libraries: Current Capabilities and Future Possibilities. Epitope Mapping with Peptides. Active Immunization Using Synthetic Peptides.

Details

No. of pages:
511
Language:
English
Copyright:
© Academic Press 1995
Published:
Imprint:
Academic Press
eBook ISBN:
9780080538594
Hardcover ISBN:
9780123109200

About the Editor

Bernd Gutte

Affiliations and Expertise

Biochemisches Institut der Universitat urich, Zurich, Switzerland