Pediatric Neurology, Part I, Volume 111

1st Edition

Editors: Olivier Dulac Maryse Lassonde Harvey Sarnat
Hardcover ISBN: 9780444528919
eBook ISBN: 9780444626981
Imprint: Elsevier
Published Date: 21st May 2013
Page Count: 892
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Table of Contents

1. Normal psychomotor development - G. Cioni and G. Sgandurra (Pisa, Italy)
2. Clinical neurological examination of infants and children - R.H.A. Haslam (Toronto, Canada)
3. Pediatric neurology – the diagnostic process - B.G.R. Neville (London, UK)
4. Health outcomes measurement: concepts, guidelines and opportunities - G.M. Ronen and P.L. Rosenbaum (Hamilton, Canada)
5. Coma - F.J. Kirkham and S. Ashwal (London, UK and Loma Linda, USA)
6. Clinical and imaging diagnosis for heredodegenerative diseases - N. Boddaert, F. Brunelle and I. Desguerre (Paris, France)
7. Developmental aspects of normal EEG - P. Plouin, A. Kaminska, M-L. Moutard and C. Soufflet (Paris, France)
8. Clinical neurophysiology in movement disorders - E. Apartis (Paris, France)
9. Announcing the diagnosis: counselling the parents - D. Taylor and P. Le Coz (London, UK and Marseilles, France)
10. Chronic paediatric diseases into adulthood and the challenge of adolescence - D. Sommelet (Vandoeuvre Les Nancy, France)
11. Ethical considerations in pediatric neurology - G.M. Ronen and B. Dan (Hamilton, Canada and Brussels, Belgium)

12. Neuroembryology and brain malformations: an overview - H.B. Sarnat and L. Flores-Sarnat (Calgary, Canada)
13. Microcephaly - S. Passemard, A. Verloes and A.M. Kaindl (Paris, France and Berlin, Germany)
14. Prenatal-onset neurodevelopmental disorders secondary to toxins, nutritional deficiencies and maternal illness - W.D. Graf, M.V. Kekatpure and B.E. Kosofsky (Kansas City and New York, USA)

15. Epidemiology of cerebral palsy - K. Himmelmann (Göteborg, Sweden)
16. Pathophysiology of cerebral palsy - S. Marret, C. Vanhulle and A. Laquerriere (Rouen, France)
17. Imaging cerebral palsy - M. Staudt (Tübingen, Germany)
18. Cerebral palsy: d


The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults.

Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research.

Since the infectious context, the genetic background and medical practice vary thr

Key Features

  • A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology
  • International list of contributors including the leading workers in the field
  • Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care


Neurologists, paediatric neurologists and neuroscientists


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© Elsevier 2013
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"Dulac…and coeditors Lassonde and Sarnat present the first in three volumes on pediatric neurology aimed at clinicians and neuroscientists, which was excluded from previous volumes in the series. It consists of 84 chapters by an international group of neurologists, neuroscientists, pediatricians, and others, on normal psychomotor development, neurological examination, diagnosis, health outcomes measurement, coma and brain death, heredodegenerative disorders,…" --Reference & Research Book News, December 2013

"This is a much-needed book, as it encompasses the entire spectrum of child neurology, from behavioral-developmental disorders to the core of both common and rare neurological diseases that affect infants, children, and adolescents…The international collection of authors provides a unique reference that will appeal to both clinicians and neuroscientists from around the globe.", November 2013

About the Editors

Olivier Dulac Editor

Affiliations and Expertise

Hopital Necker, Paris, France.

Maryse Lassonde Editor

Affiliations and Expertise

Centre de Recherche en Neuropsychologie et Cognition, Departement de Psychologie, Universite de Montreal, Quebec, Canada

Harvey Sarnat Editor

Affiliations and Expertise

University of Calgary, Faculty of Medicine; Division Chief, Paediatric Neurology, Alberta Children's Hospital, Calgary, Alberta, Canada