Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America

1st Edition, Volume 49-4 - November 7, 2020
Editor: Andrea Kelly
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 9 1 1 - 3
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 9 1 2 - 0

This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant… Read more

Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America

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This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Endocrine Sequelae in Childhood Cancer Survivors, Bone Health in Childhood Chronic Disease, Advances in Bone Health Assessment, Inhaled Glucocorticoids and Endocrine Outcomes, Atypical DM (mitochondrial, transplant, CFRD, monogenic), Pediatric Thyroid Cancer (outcomes, genetics, therapeutics), New Technologies in Type 1 diabetes (bionic pancreas, insulin, mobile health), Precocious and Delayed Puberty—Genetic Underpinnings and treatments (various GNRH formulations, implant), Pediatric Type 2 diabetes, Adolescent health outcomes in relation to phthalates.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Endocrine Sequelae in Childhood Cancer Survivors
Key points
Introduction
Cancer treatments and associated endocrine late effects
Surveillance for endocrine late effects in childhood cancer survivors
Management of endocrine late effects in childhood cancer survivors
Summary
Pediatric Thyroid Cancer: Genetics, Therapeutics and Outcome
Key points
Introduction
Cause and genetics of differentiated thyroid carcinoma
Cause and genetics of medullary thyroid carcinoma
Diagnostic evaluation of thyroid nodule
Surgical management
Medical therapy
Persistent and recurrent disease
Future directions
Advances in the Bone Health Assessment of Children
Key points
Introduction
An overview of bone health assessment techniques in children
Bone imaging methods by skeletal site and their clinical applicability
Spine
Long bones
Hand
Total body
Summary and future directions
Bone Health in Childhood Chronic Disease
Key points
Introduction
Disorders associated with impaired bone health
Clinical approach
Summary
Inhaled Corticosteroids and Endocrine Effects in Childhood
Key points
Introduction
Important differences in inhaled corticosteroids characteristics, delivery, and absorption
Adrenal insufficiency in inhaled corticosteroid–treated children
Growth effects of inhaled corticosteroids
Inhaled corticosteroids and bone metabolism
Summary
New and Emerging Technologies in Type 1 Diabetes
Key points
New technologies in type 1 diabetes
Glucose monitoring
Insulin
Insulin delivery modalities
Data management and telehealth
Summary
Pediatric Type 2 Diabetes: Not a Mini Version of Adult Type 2 Diabetes
Key points
Introduction
Pathophysiology and genetics of pediatric type 2 diabetes
Prevalence, Incidence, and Demographics of Pediatric Type 2 Diabetes
Screening and diagnosis of pediatric type 2 diabetes mellitus
Comorbidities in pediatric type 2 diabetes mellitus
Treatment of pediatric type 2 diabetes mellitus
Progression of pediatric type 2 diabetes mellitus
Complications of pediatric type 2 diabetes
Monitoring for comorbidities and complications
Summary and future directions
Overview of Atypical Diabetes
Key points
Introduction
Monogenic diabetes
Mitochondrial diabetes mellitus
Cystic fibrosis–related diabetes
Summary
Insights into the Genetic Underpinnings of Endocrine Traits from Large-Scale Genome-Wide Association Studies
Key points
Introduction
Summary
Delayed and Precocious Puberty: Genetic Underpinnings and Treatments
Key points
Introduction
Content
Summary
Phthalate Exposure, Adolescent Health, and the Need for Primary Prevention
Key points
Introduction
Hormonal mechanisms of phthalate action
Phthalates and adiposity
Phthalates and pubertal development
Phthalates and neurodevelopment
Reducing phthalate exposures
Summary